start (aa) | end (aa) | feature | details | |
308 | 308 | MUTAGEN | S->N: Abolishes phosphorylation by AURKA and interferes with cell cycle progression from G2 to mitosis. | might get lost (downstream of altered splice site) |
308 | 308 | MOD_RES | Phosphoserine; by AURKA. | might get lost (downstream of altered splice site) |
395 | 395 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
398 | 398 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
403 | 403 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
651 | 654 | COMPBIAS | Poly-Lys. | might get lost (downstream of altered splice site) |
753 | 753 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
840 | 840 | MOD_RES | Phosphoserine (By similarity). | might get lost (downstream of altered splice site) |
988 | 988 | MOD_RES | Phosphoserine; by CHEK2. | might get lost (downstream of altered splice site) |
1077 | 1077 | CONFLICT | G -> R (in Ref. 4; AAB61673). | might get lost (downstream of altered splice site) |
1143 | 1143 | MUTAGEN | S->A: Reduces in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1143 | 1143 | MOD_RES | Phosphoserine; by ATR; in vitro. | might get lost (downstream of altered splice site) |
1211 | 1211 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1212 | 1212 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1217 | 1217 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1218 | 1218 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1239 | 1239 | MUTAGEN | S->A: No effect on in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1239 | 1239 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1245 | 1245 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1280 | 1280 | MOD_RES | Phosphoserine; by ATR; in vitro. | might get lost (downstream of altered splice site) |
1280 | 1280 | MUTAGEN | S->A: Reduces in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1298 | 1298 | MUTAGEN | S->A: No effect on in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1330 | 1330 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1330 | 1330 | MUTAGEN | S->A: No effect on in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1336 | 1336 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1342 | 1342 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1387 | 1387 | MUTAGEN | S->A: Loss of IR-induced S-phase checkpoint. Reduces in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1387 | 1387 | MOD_RES | Phosphoserine; by ATM and ATR. | might get lost (downstream of altered splice site) |
1394 | 1394 | MUTAGEN | T->A: Reduces in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1394 | 1394 | MOD_RES | Phosphothreonine; by ATR; in vitro. | might get lost (downstream of altered splice site) |
1397 | 1424 | REGION | Interaction with PALB2. | might get lost (downstream of altered splice site) |
1423 | 1423 | MOD_RES | Phosphoserine; by ATM and ATR. | might get lost (downstream of altered splice site) |
1423 | 1423 | MUTAGEN | S->A: Inhibition of the infrared-induced G2 arrest. Reduces phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1426 | 1426 | CONFLICT | S -> P (in Ref. 3; AAC00049). | might get lost (downstream of altered splice site) |
1453 | 1453 | CONFLICT | Missing (in Ref. 3; AAC00049). | might get lost (downstream of altered splice site) |
1457 | 1457 | MOD_RES | Phosphoserine; by ATR; in vitro. | might get lost (downstream of altered splice site) |
1457 | 1457 | MUTAGEN | S->A: Reduces in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1466 | 1466 | MUTAGEN | S->A: No effect on in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1466 | 1466 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1524 | 1524 | MUTAGEN | S->A: No change in infrared S-phase delay; when associated with A-1387. No effect on in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1524 | 1524 | MOD_RES | Phosphoserine; by ATM. | might get lost (downstream of altered splice site) |
1542 | 1542 | MOD_RES | Phosphoserine. | might get lost (downstream of altered splice site) |
1642 | 1736 | DOMAIN | BRCT 1. | might get lost (downstream of altered splice site) |
1651 | 1656 | STRAND | | might get lost (downstream of altered splice site) |
1655 | 1655 | MUTAGEN | S->A: Abolishes interaction with BRIP1. | might get lost (downstream of altered splice site) |
1659 | 1672 | HELIX | | might get lost (downstream of altered splice site) |
1675 | 1679 | STRAND | | might get lost (downstream of altered splice site) |
1686 | 1689 | STRAND | | might get lost (downstream of altered splice site) |
1695 | 1697 | STRAND | | might get lost (downstream of altered splice site) |
1700 | 1700 | MOD_RES | Phosphothreonine. | might get lost (downstream of altered splice site) |
1701 | 1708 | HELIX | | might get lost (downstream of altered splice site) |
1702 | 1702 | MUTAGEN | K->M: Abolishes interaction with BRIP1. | might get lost (downstream of altered splice site) |
1712 | 1715 | STRAND | | might get lost (downstream of altered splice site) |
1717 | 1724 | HELIX | | might get lost (downstream of altered splice site) |
1720 | 1720 | MUTAGEN | T->A: No effect on in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1720 | 1720 | MOD_RES | Phosphothreonine. | might get lost (downstream of altered splice site) |
1725 | 1727 | STRAND | | might get lost (downstream of altered splice site) |
1731 | 1734 | HELIX | | might get lost (downstream of altered splice site) |
1738 | 1738 | MUTAGEN | G->E: Abolishes interaction with BRIP1. | might get lost (downstream of altered splice site) |
1740 | 1742 | TURN | | might get lost (downstream of altered splice site) |
1743 | 1745 | STRAND | | might get lost (downstream of altered splice site) |
1748 | 1753 | HELIX | | might get lost (downstream of altered splice site) |
1755 | 1755 | MUTAGEN | S->A: No effect on in vitro phosphorylation by ATR. | might get lost (downstream of altered splice site) |
1755 | 1757 | TURN | | might get lost (downstream of altered splice site) |
1756 | 1855 | DOMAIN | BRCT 2. | might get lost (downstream of altered splice site) |
1760 | 1763 | TURN | | might get lost (downstream of altered splice site) |
1765 | 1768 | STRAND | | might get lost (downstream of altered splice site) |
1770 | 1772 | STRAND | | might get lost (downstream of altered splice site) |
1773 | 1775 | STRAND | | might get lost (downstream of altered splice site) |
1777 | 1786 | HELIX | | might get lost (downstream of altered splice site) |
1789 | 1791 | STRAND | | might get lost (downstream of altered splice site) |
1795 | 1797 | HELIX | | might get lost (downstream of altered splice site) |
1801 | 1803 | STRAND | | might get lost (downstream of altered splice site) |
1806 | 1810 | STRAND | | might get lost (downstream of altered splice site) |
1812 | 1814 | HELIX | | might get lost (downstream of altered splice site) |
1819 | 1822 | HELIX | | might get lost (downstream of altered splice site) |
1825 | 1827 | TURN | | might get lost (downstream of altered splice site) |
1828 | 1830 | STRAND | | might get lost (downstream of altered splice site) |
1832 | 1834 | STRAND | | might get lost (downstream of altered splice site) |
1835 | 1844 | HELIX | | might get lost (downstream of altered splice site) |
1851 | 1853 | HELIX | | might get lost (downstream of altered splice site) |