Yum, tasty mutations...

MutationTaster - study a chromosomal position

 MTQE documentation
NEVER press reload or F5 - unless you want to start from the very beginning.
input seems to be ok - now mapping the variant to the different transcripts...
found 2 transcript(s)...
Querying Taster for transcript #1: ENST00000354618
Querying Taster for transcript #2: ENST00000469141
MT speed 0 s - this script 3.55057 s

Results

genesymbolpredictionprobabilitymodelprediction
problem		splicingClinVaramino acid changesvariant typedbSNP IDprotein lengthfile
THRAP3polymorphism_automatic0.736968729811017simple_aaeaffectedA201Vsingle base exchangers6425977show file
THRAP3polymorphism_automatic0.736968729811017simple_aaeaffectedA201Vsingle base exchangers6425977show file

Taster files

Yum, tasty mutations...

mutation t@sting

 documentation

Prediction

polymorphism

 Model: simple_aae, prob: 0.263031270188983 (classification due to TGP/ExAC, real probability is shown anyway)      (explain)
Summary
  • amino acid sequence changed
  • homozygous in TGP or ExAC
  • protein features (might be) affected
  • splice site changes
 hyperlink
analysed issue analysis result
name of alteration no title
alteration (phys. location) chr1:36752433C>TN/A show variant in all transcripts   IGV
HGNC symbol THRAP3
Ensembl transcript ID ENST00000354618
Genbank transcript ID NM_005119
UniProt peptide Q9Y2W1
alteration type single base exchange
alteration region CDS
DNA changes c.602C>T
cDNA.826C>T
g.62417C>T
AA changes A201V Score: 64 explain score(s)
position(s) of altered AA
if AA alteration in CDS		 201
frameshift no
known variant Reference ID: rs6425977
databasehomozygous (T/T)heterozygousallele carriers
1000G16686482316
ExAC---
regulatory features H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation
phyloP / phastCons
PhyloPPhastCons
(flanking)-0.1570.791
2.6820.996
(flanking)1.0630.999
explain score(s) and/or inspect your position(s) in in UCSC Genome Browser
splice sites
effectgDNA positionscorewt detection sequence exon-intron border
Donor marginally increased62415wt: 0.9977 / mu: 0.9978 (marginal change - not scored)wt: GATGAGGCCAAGGAG
mu: GATGAGGTCAAGGAG		 TGAG|gcca
Donor increased62421wt: 0.51 / mu: 0.70wt: GCCAAGGAGCAGACA
mu: GTCAAGGAGCAGACA		 CAAG|gagc
distance from splice site 439
Kozak consensus sequence altered? N/A
conservation
protein level for non-synonymous changes
speciesmatchgeneaaalignment
Human      201SQAAGDNQGDEAKEQTFSGGTSQD
mutated  not conserved    201SQAAGDNQGDEVKEQTFSGGTSQ
Ptroglodytes  all identical  ENSPTRG00000000535  201SQAAGDNQGDEAKEQTFSGGTSQ
Mmulatta  all identical  ENSMMUG00000014622  201SQAAGDNQGDEAKDQTFSGGTSQ
Fcatus  no homologue    
Mmusculus  all identical  ENSMUSG00000043962  201SQAAGDNQGDEAKEQTFSGGTSQ
Ggallus  all conserved  ENSGALG00000002144  201SQAAGDNQGDDSKEQPFSGAAAQ
Trubripes  all conserved  ENSTRUG00000010336  72YHYRGRNRGYYSRGGGGGGGG--
Drerio  all identical  ENSDARG00000003513  199RGSPGESKG-AAKEASKPTGSPP
Dmelanogaster  no homologue    
Celegans  no homologue    
Xtropicalis  all conserved  ENSXETG00000003925  198SAQAVD---DDSKEQSGSGGPDT
protein features
start (aa)end (aa)featuredetails 
7339COMPBIASSer-rich.lost
207207MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
211211MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
221221MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
232232MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
237237MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
240240MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
243243MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
248248MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
253253MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
264264MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
268268MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
310310MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
315315MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
320320MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
323323MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
324324MOD_RESPhosphothreonine (By similarity).might get lost (downstream of altered splice site)
328328MOD_RESPhosphotyrosine.might get lost (downstream of altered splice site)
377377MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
379379MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
401401MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
406406MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
408408MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
444444MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
455455MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
508508MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
519519MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
534534MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
535535MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
552559NP_BINDATP (Potential).might get lost (downstream of altered splice site)
562562MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
575575MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
662662MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
672672MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
682682MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
684684MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
685685MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
698698MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
709709MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
811811MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
823823MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
833833MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
874874MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
928928MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
939939MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
941941MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
length of protein normal
AA sequence altered yes
position of stopcodon in wt / mu CDS 2868 / 2868
position (AA) of stopcodon in wt / mu AA sequence 956 / 956
position of stopcodon in wt / mu cDNA 3092 / 3092
poly(A) signal N/A
conservation
nucleotide level for all changes - no scoring up to now		 N/A
position of start ATG in wt / mu cDNA 225 / 225
chromosome 1
strand 1
last intron/exon boundary 2871
theoretical NMD boundary in CDS 2596
length of CDS 2868
coding sequence (CDS) position 602
cDNA position
(for ins/del: last normal base / first normal base)		 826
gDNA position
(for ins/del: last normal base / first normal base)		 62417
chromosomal position
(for ins/del: last normal base / first normal base)		 36752433
original gDNA sequence snippet GGATAACCAGGGAGATGAGGCCAAGGAGCAGACATTCTCTG
altered gDNA sequence snippet GGATAACCAGGGAGATGAGGTCAAGGAGCAGACATTCTCTG
original cDNA sequence snippet GGATAACCAGGGAGATGAGGCCAAGGAGCAGACATTCTCTG
altered cDNA sequence snippet GGATAACCAGGGAGATGAGGTCAAGGAGCAGACATTCTCTG
wildtype AA sequence MSKTNKSKSG SRSSRSRSAS RSRSRSFSKS RSRSRSLSRS RKRRLSSRSR SRSYSPAHNR
ERNHPRVYQN RDFRGHNRGY RRPYYFRGRN RGFYPWGQYN RGGYGNYRSN WQNYRQAYSP
RRGRSRSRSP KRRSPSPRSR SHSRNSDKSS SDRSRRSSSS RSSSNHSRVE SSKRKSAKEK
KSSSKDSRPS QAAGDNQGDE AKEQTFSGGT SQDTKASESS KPWPDATYGT GSASRASAVS
ELSPRERSPA LKSPLQSVVV RRRSPRPSPV PKPSPPLSST SQMGSTLPSG AGYQSGTHQG
QFDHGSGSLS PSKKSPVGKS PPSTGSTYGS SQKEESAASG GAAYTKRYLE EQKTENGKDK
EQKQTNTDKE KIKEKGSFSD TGLGDGKMKS DSFAPKTDSE KPFRGSQSPK RYKLRDDFEK
KMADFHKEEM DDQDKDKAKG RKESEFDDEP KFMSKVIGAN KNQEEEKSGK WEGLVYAPPG
KEKQRKTEEL EEESFPERSK KEDRGKRSEG GHRGFVPEKN FRVTAYKAVQ EKSSSPPPRK
TSESRDKLGA KGDFPTGKSS FSITREAQVN VRMDSFDEDL ARPSGLLAQE RKLCRDLVHS
NKKEQEFRSI FQHIQSAQSQ RSPSELFAQH IVTIVHHVKE HHFGSSGMTL HERFTKYLKR
GTEQEAAKNK KSPEIHRRID ISPSTFRKHG LAHDEMKSPR EPGYKAEGKY KDDPVDLRLD
IERRKKHKER DLKRGKSRES VDSRDSSHSR ERSAEKTEKT HKGSKKQKKH RRARDRSRSS
SSSSQSSHSY KAEEYTEETE EREESTTGFD KSRLGTKDFV GPSERGGGRA RGTFQFRARG
RGWGRGNYSG NNNNNSNNDF QKRNREEEWD PEYTPKSKKY YLHDDREGEG SDKWVSRGRG
RGAFPRGRGR FMFRKSSTSP KWAHDKFSGE EGEIEDDESG TENREEKDNI QPTTE*
mutated AA sequence MSKTNKSKSG SRSSRSRSAS RSRSRSFSKS RSRSRSLSRS RKRRLSSRSR SRSYSPAHNR
ERNHPRVYQN RDFRGHNRGY RRPYYFRGRN RGFYPWGQYN RGGYGNYRSN WQNYRQAYSP
RRGRSRSRSP KRRSPSPRSR SHSRNSDKSS SDRSRRSSSS RSSSNHSRVE SSKRKSAKEK
KSSSKDSRPS QAAGDNQGDE VKEQTFSGGT SQDTKASESS KPWPDATYGT GSASRASAVS
ELSPRERSPA LKSPLQSVVV RRRSPRPSPV PKPSPPLSST SQMGSTLPSG AGYQSGTHQG
QFDHGSGSLS PSKKSPVGKS PPSTGSTYGS SQKEESAASG GAAYTKRYLE EQKTENGKDK
EQKQTNTDKE KIKEKGSFSD TGLGDGKMKS DSFAPKTDSE KPFRGSQSPK RYKLRDDFEK
KMADFHKEEM DDQDKDKAKG RKESEFDDEP KFMSKVIGAN KNQEEEKSGK WEGLVYAPPG
KEKQRKTEEL EEESFPERSK KEDRGKRSEG GHRGFVPEKN FRVTAYKAVQ EKSSSPPPRK
TSESRDKLGA KGDFPTGKSS FSITREAQVN VRMDSFDEDL ARPSGLLAQE RKLCRDLVHS
NKKEQEFRSI FQHIQSAQSQ RSPSELFAQH IVTIVHHVKE HHFGSSGMTL HERFTKYLKR
GTEQEAAKNK KSPEIHRRID ISPSTFRKHG LAHDEMKSPR EPGYKAEGKY KDDPVDLRLD
IERRKKHKER DLKRGKSRES VDSRDSSHSR ERSAEKTEKT HKGSKKQKKH RRARDRSRSS
SSSSQSSHSY KAEEYTEETE EREESTTGFD KSRLGTKDFV GPSERGGGRA RGTFQFRARG
RGWGRGNYSG NNNNNSNNDF QKRNREEEWD PEYTPKSKKY YLHDDREGEG SDKWVSRGRG
RGAFPRGRGR FMFRKSSTSP KWAHDKFSGE EGEIEDDESG TENREEKDNI QPTTE*
speed 0.36 s
All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table
Yum, tasty mutations...

mutation t@sting

 documentation

Prediction

polymorphism

 Model: simple_aae, prob: 0.263031270188983 (classification due to TGP/ExAC, real probability is shown anyway)      (explain)
Summary
  • amino acid sequence changed
  • homozygous in TGP or ExAC
  • protein features (might be) affected
  • splice site changes
 hyperlink
analysed issue analysis result
name of alteration no title
alteration (phys. location) chr1:36752433C>TN/A show variant in all transcripts   IGV
HGNC symbol THRAP3
Ensembl transcript ID ENST00000469141
Genbank transcript ID N/A
UniProt peptide Q9Y2W1
alteration type single base exchange
alteration region CDS
DNA changes c.602C>T
cDNA.942C>T
g.62417C>T
AA changes A201V Score: 64 explain score(s)
position(s) of altered AA
if AA alteration in CDS		 201
frameshift no
known variant Reference ID: rs6425977
databasehomozygous (T/T)heterozygousallele carriers
1000G16686482316
ExAC---
regulatory features H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation
phyloP / phastCons
PhyloPPhastCons
(flanking)-0.1570.791
2.6820.996
(flanking)1.0630.999
explain score(s) and/or inspect your position(s) in in UCSC Genome Browser
splice sites
effectgDNA positionscorewt detection sequence exon-intron border
Donor marginally increased62415wt: 0.9977 / mu: 0.9978 (marginal change - not scored)wt: GATGAGGCCAAGGAG
mu: GATGAGGTCAAGGAG		 TGAG|gcca
Donor increased62421wt: 0.51 / mu: 0.70wt: GCCAAGGAGCAGACA
mu: GTCAAGGAGCAGACA		 CAAG|gagc
distance from splice site 439
Kozak consensus sequence altered? N/A
conservation
protein level for non-synonymous changes
speciesmatchgeneaaalignment
Human      201SQAAGDNQGDEAKEQTFSGGTSQD
mutated  not conserved    201SQAAGDNQGDEVKEQTFSGGTSQ
Ptroglodytes  all identical  ENSPTRG00000000535  201SQAAGDNQGDEAKEQTFSGGTSQ
Mmulatta  all identical  ENSMMUG00000014622  201SQAAGDNQGDEAKDQTFSGGTSQ
Fcatus  no homologue    
Mmusculus  all identical  ENSMUSG00000043962  201SQAAGDNQGDEAKEQTFSGGTSQ
Ggallus  all conserved  ENSGALG00000002144  201SQAAGDNQGDDSKEQPFSGAAAQ
Trubripes  all conserved  ENSTRUG00000010336  72YHYRGRNRGYYSRGGGGGGGG--
Drerio  all identical  ENSDARG00000003513  199RGSPGESKG-AAKEASKPTGSPP
Dmelanogaster  no homologue    
Celegans  no homologue    
Xtropicalis  all conserved  ENSXETG00000003925  198SAQAVD---DDSKEQSGSGGPDT
protein features
start (aa)end (aa)featuredetails 
7339COMPBIASSer-rich.lost
207207MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
211211MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
221221MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
232232MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
237237MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
240240MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
243243MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
248248MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
253253MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
264264MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
268268MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
310310MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
315315MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
320320MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
323323MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
324324MOD_RESPhosphothreonine (By similarity).might get lost (downstream of altered splice site)
328328MOD_RESPhosphotyrosine.might get lost (downstream of altered splice site)
377377MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
379379MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
401401MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
406406MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
408408MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
444444MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
455455MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
508508MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
519519MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
534534MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
535535MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
552559NP_BINDATP (Potential).might get lost (downstream of altered splice site)
562562MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
575575MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
662662MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
672672MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
682682MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
684684MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
685685MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
698698MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
709709MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
811811MOD_RESN6-acetyllysine.might get lost (downstream of altered splice site)
823823MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
833833MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
874874MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
928928MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
939939MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
941941MOD_RESPhosphothreonine.might get lost (downstream of altered splice site)
length of protein normal
AA sequence altered yes
position of stopcodon in wt / mu CDS 2868 / 2868
position (AA) of stopcodon in wt / mu AA sequence 956 / 956
position of stopcodon in wt / mu cDNA 3208 / 3208
poly(A) signal N/A
conservation
nucleotide level for all changes - no scoring up to now		 N/A
position of start ATG in wt / mu cDNA 341 / 341
chromosome 1
strand 1
last intron/exon boundary 2987
theoretical NMD boundary in CDS 2596
length of CDS 2868
coding sequence (CDS) position 602
cDNA position
(for ins/del: last normal base / first normal base)		 942
gDNA position
(for ins/del: last normal base / first normal base)		 62417
chromosomal position
(for ins/del: last normal base / first normal base)		 36752433
original gDNA sequence snippet GGATAACCAGGGAGATGAGGCCAAGGAGCAGACATTCTCTG
altered gDNA sequence snippet GGATAACCAGGGAGATGAGGTCAAGGAGCAGACATTCTCTG
original cDNA sequence snippet GGATAACCAGGGAGATGAGGCCAAGGAGCAGACATTCTCTG
altered cDNA sequence snippet GGATAACCAGGGAGATGAGGTCAAGGAGCAGACATTCTCTG
wildtype AA sequence MSKTNKSKSG SRSSRSRSAS RSRSRSFSKS RSRSRSLSRS RKRRLSSRSR SRSYSPAHNR
ERNHPRVYQN RDFRGHNRGY RRPYYFRGRN RGFYPWGQYN RGGYGNYRSN WQNYRQAYSP
RRGRSRSRSP KRRSPSPRSR SHSRNSDKSS SDRSRRSSSS RSSSNHSRVE SSKRKSAKEK
KSSSKDSRPS QAAGDNQGDE AKEQTFSGGT SQDTKASESS KPWPDATYGT GSASRASAVS
ELSPRERSPA LKSPLQSVVV RRRSPRPSPV PKPSPPLSST SQMGSTLPSG AGYQSGTHQG
QFDHGSGSLS PSKKSPVGKS PPSTGSTYGS SQKEESAASG GAAYTKRYLE EQKTENGKDK
EQKQTNTDKE KIKEKGSFSD TGLGDGKMKS DSFAPKTDSE KPFRGSQSPK RYKLRDDFEK
KMADFHKEEM DDQDKDKAKG RKESEFDDEP KFMSKVIGAN KNQEEEKSGK WEGLVYAPPG
KEKQRKTEEL EEESFPERSK KEDRGKRSEG GHRGFVPEKN FRVTAYKAVQ EKSSSPPPRK
TSESRDKLGA KGDFPTGKSS FSITREAQVN VRMDSFDEDL ARPSGLLAQE RKLCRDLVHS
NKKEQEFRSI FQHIQSAQSQ RSPSELFAQH IVTIVHHVKE HHFGSSGMTL HERFTKYLKR
GTEQEAAKNK KSPEIHRRID ISPSTFRKHG LAHDEMKSPR EPGYKAEGKY KDDPVDLRLD
IERRKKHKER DLKRGKSRES VDSRDSSHSR ERSAEKTEKT HKGSKKQKKH RRARDRSRSS
SSSSQSSHSY KAEEYTEETE EREESTTGFD KSRLGTKDFV GPSERGGGRA RGTFQFRARG
RGWGRGNYSG NNNNNSNNDF QKRNREEEWD PEYTPKSKKY YLHDDREGEG SDKWVSRGRG
RGAFPRGRGR FMFRKSSTSP KWAHDKFSGE EGEIEDDESG TENREEKDNI QPTTE*
mutated AA sequence MSKTNKSKSG SRSSRSRSAS RSRSRSFSKS RSRSRSLSRS RKRRLSSRSR SRSYSPAHNR
ERNHPRVYQN RDFRGHNRGY RRPYYFRGRN RGFYPWGQYN RGGYGNYRSN WQNYRQAYSP
RRGRSRSRSP KRRSPSPRSR SHSRNSDKSS SDRSRRSSSS RSSSNHSRVE SSKRKSAKEK
KSSSKDSRPS QAAGDNQGDE VKEQTFSGGT SQDTKASESS KPWPDATYGT GSASRASAVS
ELSPRERSPA LKSPLQSVVV RRRSPRPSPV PKPSPPLSST SQMGSTLPSG AGYQSGTHQG
QFDHGSGSLS PSKKSPVGKS PPSTGSTYGS SQKEESAASG GAAYTKRYLE EQKTENGKDK
EQKQTNTDKE KIKEKGSFSD TGLGDGKMKS DSFAPKTDSE KPFRGSQSPK RYKLRDDFEK
KMADFHKEEM DDQDKDKAKG RKESEFDDEP KFMSKVIGAN KNQEEEKSGK WEGLVYAPPG
KEKQRKTEEL EEESFPERSK KEDRGKRSEG GHRGFVPEKN FRVTAYKAVQ EKSSSPPPRK
TSESRDKLGA KGDFPTGKSS FSITREAQVN VRMDSFDEDL ARPSGLLAQE RKLCRDLVHS
NKKEQEFRSI FQHIQSAQSQ RSPSELFAQH IVTIVHHVKE HHFGSSGMTL HERFTKYLKR
GTEQEAAKNK KSPEIHRRID ISPSTFRKHG LAHDEMKSPR EPGYKAEGKY KDDPVDLRLD
IERRKKHKER DLKRGKSRES VDSRDSSHSR ERSAEKTEKT HKGSKKQKKH RRARDRSRSS
SSSSQSSHSY KAEEYTEETE EREESTTGFD KSRLGTKDFV GPSERGGGRA RGTFQFRARG
RGWGRGNYSG NNNNNSNNDF QKRNREEEWD PEYTPKSKKY YLHDDREGEG SDKWVSRGRG
RGAFPRGRGR FMFRKSSTSP KWAHDKFSGE EGEIEDDESG TENREEKDNI QPTTE*
speed 1.19 s
All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table

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