MutationTaster - study a chromosomal position

NEVER press reload or F5 - unless you want to start from the very beginning.
input seems to be ok - now mapping the variant to the different transcripts...
found 8 transcript(s)...
Querying Taster for transcript #1: ENST00000572705
Querying Taster for transcript #2: ENST00000399759
Querying Taster for transcript #3: ENST00000571088
Querying Taster for transcript #4: ENST00000399756
Querying Taster for transcript #5: ENST00000425167
Querying Taster for transcript #6: ENST00000576351
Querying Taster for transcript #7: ENST00000310522
Querying Taster for transcript #8: ENST00000174621
MT speed 0 s - this script 4.101501 s

Results

genesymbol	prediction	probability	model	prediction problem	splicing	ClinVar	amino acid changes	variant type	dbSNP ID	protein length	file
TRPV1	polymorphism_automatic	5.62767055178881e-10	simple_aae				T469I	single base exchange	rs224534		show file
TRPV1	polymorphism_automatic	5.62767055178881e-10	simple_aae				T469I	single base exchange	rs224534		show file
TRPV1	polymorphism_automatic	5.62767055178881e-10	simple_aae				T469I	single base exchange	rs224534		show file
TRPV1	polymorphism_automatic	5.62767055178881e-10	simple_aae				T459I	single base exchange	rs224534		show file
TRPV1	polymorphism_automatic	5.62767055178881e-10	simple_aae				T409I	single base exchange	rs224534		show file
TRPV1	polymorphism_automatic	5.62767055178881e-10	simple_aae				T467I	single base exchange	rs224534		show file
TRPV1	polymorphism_automatic	2.74047899928576e-08	simple_aae				T480I	single base exchange	rs224534		show file

Taster files

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999437233 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
known disease mutation at this position (HGMD CM163259)
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr17:3486702G>AN/A show variant in all transcripts IGV

HGNC symbol

TRPV1

Ensembl transcript ID

ENST00000399759

Genbank transcript ID

NM_080705

UniProt peptide

Q8NER1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.1406C>T
cDNA.1607C>T
g.13691C>T

AA changes

T469I Score: 89 explain score(s)

position(s) of altered AA
if AA alteration in CDS

469

frameshift

known variant

Reference ID: rs224534

database	homozygous (A/A)	heterozygous	allele carriers
1000G	539	815	1354
ExAC	8709	15349	24058

known disease mutation at this position, please check HGMD for details (HGMD ID CM163259)

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	-0.041	0.012
	0.5	0.003
(flanking)	1.555	0.007

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

469

mutated

not conserved

469

Ptroglodytes

all identical

ENSPTRG00000024045

457

Mmulatta

all identical

ENSMMUG00000000711

469

Fcatus

no homologue

Mmusculus

not conserved

ENSMUSG00000005952

469

Ggallus

all identical

ENSGALG00000004649

474

QKG

Trubripes

no homologue

Drerio

all conserved

ENSDARG00000059883

430

EGKDYAN

Dmelanogaster

not conserved

FBgn0036414

510

Celegans

not conserved

B0212.5

425

EDP

Xtropicalis

not conserved

ENSXETG00000005790

479

protein features

start (aa)	end (aa)	feature	details
455	476	TOPO_DOM	Extracellular (Potential).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2520 / 2520

position (AA) of stopcodon in wt / mu AA sequence

840 / 840

position of stopcodon in wt / mu cDNA

2721 / 2721

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

202 / 202

chromosome

strand

-1

last intron/exon boundary

2549

theoretical NMD boundary in CDS

2297

length of CDS

2520

coding sequence (CDS) position

1406

cDNA position
(for ins/del: last normal base / first normal base)

1607

gDNA position
(for ins/del: last normal base / first normal base)

13691

chromosomal position
(for ins/del: last normal base / first normal base)

3486702

original gDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered gDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

original cDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered cDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

wildtype AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGVL AYILQREIQE
PECRHLSRKF TEWAYGPVHS SLYDLSCIDT CEKNSVLEVI AYSSSETPNR HDMLLVEPLN
RLLQDKWDRF VKRIFYFNFL VYCLYMIIFT MAAYYRPVDG LPPFKMEKTG DYFRVTGEIL
SVLGGVYFFF RGIQYFLQRR PSMKTLFVDS YSEMLFFLQS LFMLATVVLY FSHLKEYVAS
MVFSLALGWT NMLYYTRGFQ QMGIYAVMIE KMILRDLCRF MFVYIVFLFG FSTAVVTLIE
DGKNDSLPSE STSHRWRGPA CRPPDSSYNS LYSTCLELFK FTIGMGDLEF TENYDFKAVF
IILLLAYVIL TYILLLNMLI ALMGETVNKI AQESKNIWKL QRAITILDTE KSFLKCMRKA
FRSGKLLQVG YTPDGKDDYR WCFRVDEVNW TTWNTNVGII NEDPGNCEGV KRTLSFSLRS
SRVSGRHWKN FALVPLLREA SARDRQSAQP EEVYLRQFSG SLKPEDAEVF KSPAASGEK*

mutated AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGVL AYILQREIQE
PECRHLSRKF TEWAYGPVHS SLYDLSCIDT CEKNSVLEVI AYSSSETPNR HDMLLVEPLN
RLLQDKWDRF VKRIFYFNFL VYCLYMIIFT MAAYYRPVDG LPPFKMEKIG DYFRVTGEIL
SVLGGVYFFF RGIQYFLQRR PSMKTLFVDS YSEMLFFLQS LFMLATVVLY FSHLKEYVAS
MVFSLALGWT NMLYYTRGFQ QMGIYAVMIE KMILRDLCRF MFVYIVFLFG FSTAVVTLIE
DGKNDSLPSE STSHRWRGPA CRPPDSSYNS LYSTCLELFK FTIGMGDLEF TENYDFKAVF
IILLLAYVIL TYILLLNMLI ALMGETVNKI AQESKNIWKL QRAITILDTE KSFLKCMRKA
FRSGKLLQVG YTPDGKDDYR WCFRVDEVNW TTWNTNVGII NEDPGNCEGV KRTLSFSLRS
SRVSGRHWKN FALVPLLREA SARDRQSAQP EEVYLRQFSG SLKPEDAEVF KSPAASGEK*

speed

0.31 s

All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999437233 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
known disease mutation at this position (HGMD CM163259)
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr17:3486702G>AN/A show variant in all transcripts IGV

HGNC symbol

TRPV1

Ensembl transcript ID

ENST00000571088

Genbank transcript ID

NM_018727

UniProt peptide

Q8NER1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.1406C>T
cDNA.1620C>T
g.13691C>T

AA changes

T469I Score: 89 explain score(s)

position(s) of altered AA
if AA alteration in CDS

469

frameshift

known variant

Reference ID: rs224534

database	homozygous (A/A)	heterozygous	allele carriers
1000G	539	815	1354
ExAC	8709	15349	24058

known disease mutation at this position, please check HGMD for details (HGMD ID CM163259)

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	-0.041	0.012
	0.5	0.003
(flanking)	1.555	0.007

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

469

mutated

not conserved

469

Ptroglodytes

all identical

ENSPTRG00000024045

457

Mmulatta

all identical

ENSMMUG00000000711

469

Fcatus

no homologue

Mmusculus

not conserved

ENSMUSG00000005952

469

Ggallus

all identical

ENSGALG00000004649

474

QKG

Trubripes

no homologue

Drerio

all conserved

ENSDARG00000059883

430

EGKDYAN

Dmelanogaster

not conserved

FBgn0036414

510

Celegans

not conserved

B0212.5

425

EDP

Xtropicalis

not conserved

ENSXETG00000005790

479

protein features

start (aa)	end (aa)	feature	details
455	476	TOPO_DOM	Extracellular (Potential).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2520 / 2520

position (AA) of stopcodon in wt / mu AA sequence

840 / 840

position of stopcodon in wt / mu cDNA

2734 / 2734

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

215 / 215

chromosome

strand

-1

last intron/exon boundary

2562

theoretical NMD boundary in CDS

2297

length of CDS

2520

coding sequence (CDS) position

1406

cDNA position
(for ins/del: last normal base / first normal base)

1620

gDNA position
(for ins/del: last normal base / first normal base)

13691

chromosomal position
(for ins/del: last normal base / first normal base)

3486702

original gDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered gDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

original cDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered cDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

wildtype AA sequence

mutated AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGVL AYILQREIQE
PECRHLSRKF TEWAYGPVHS SLYDLSCIDT CEKNSVLEVI AYSSSETPNR HDMLLVEPLN
RLLQDKWDRF VKRIFYFNFL VYCLYMIIFT MAAYYRPVDG LPPFKMEKIG DYFRVTGEIL
SVLGGVYFFF RGIQYFLQRR PSMKTLFVDS YSEMLFFLQS LFMLATVVLY FSHLKEYVAS
MVFSLALGWT NMLYYTRGFQ QMGIYAVMIE KMILRDLCRF MFVYIVFLFG FSTAVVTLIE
DGKNDSLPSE STSHRWRGPA CRPPDSSYNS LYSTCLELFK FTIGMGDLEF TENYDFKAVF
IILLLAYVIL TYILLLNMLI ALMGETVNKI AQESKNIWKL QRAITILDTE KSFLKCMRKA
FRSGKLLQVG YTPDGKDDYR WCFRVDEVNW TTWNTNVGII NEDPGNCEGV KRTLSFSLRS
SRVSGRHWKN FALVPLLREA SARDRQSAQP EEVYLRQFSG SLKPEDAEVF KSPAASGEK*

speed

0.33 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999437233 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
known disease mutation at this position (HGMD CM163259)
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr17:3486702G>AN/A show variant in all transcripts IGV

HGNC symbol

TRPV1

Ensembl transcript ID

ENST00000399756

Genbank transcript ID

NM_080706

UniProt peptide

Q8NER1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.1406C>T
cDNA.1933C>T
g.13691C>T

AA changes

T469I Score: 89 explain score(s)

position(s) of altered AA
if AA alteration in CDS

469

frameshift

known variant

Reference ID: rs224534

database	homozygous (A/A)	heterozygous	allele carriers
1000G	539	815	1354
ExAC	8709	15349	24058

known disease mutation at this position, please check HGMD for details (HGMD ID CM163259)

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	-0.041	0.012
	0.5	0.003
(flanking)	1.555	0.007

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

469

mutated

not conserved

469

Ptroglodytes

all identical

ENSPTRG00000024045

457

Mmulatta

all identical

ENSMMUG00000000711

469

Fcatus

no homologue

Mmusculus

not conserved

ENSMUSG00000005952

469

Ggallus

all identical

ENSGALG00000004649

474

QKG

Trubripes

no homologue

Drerio

all conserved

ENSDARG00000059883

430

EGKDYAN

Dmelanogaster

not conserved

FBgn0036414

510

Celegans

not conserved

B0212.5

425

EDP

Xtropicalis

not conserved

ENSXETG00000005790

479

protein features

start (aa)	end (aa)	feature	details
455	476	TOPO_DOM	Extracellular (Potential).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2520 / 2520

position (AA) of stopcodon in wt / mu AA sequence

840 / 840

position of stopcodon in wt / mu cDNA

3047 / 3047

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

528 / 528

chromosome

strand

-1

last intron/exon boundary

2875

theoretical NMD boundary in CDS

2297

length of CDS

2520

coding sequence (CDS) position

1406

cDNA position
(for ins/del: last normal base / first normal base)

1933

gDNA position
(for ins/del: last normal base / first normal base)

13691

chromosomal position
(for ins/del: last normal base / first normal base)

3486702

original gDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered gDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

original cDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered cDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

wildtype AA sequence

mutated AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGVL AYILQREIQE
PECRHLSRKF TEWAYGPVHS SLYDLSCIDT CEKNSVLEVI AYSSSETPNR HDMLLVEPLN
RLLQDKWDRF VKRIFYFNFL VYCLYMIIFT MAAYYRPVDG LPPFKMEKIG DYFRVTGEIL
SVLGGVYFFF RGIQYFLQRR PSMKTLFVDS YSEMLFFLQS LFMLATVVLY FSHLKEYVAS
MVFSLALGWT NMLYYTRGFQ QMGIYAVMIE KMILRDLCRF MFVYIVFLFG FSTAVVTLIE
DGKNDSLPSE STSHRWRGPA CRPPDSSYNS LYSTCLELFK FTIGMGDLEF TENYDFKAVF
IILLLAYVIL TYILLLNMLI ALMGETVNKI AQESKNIWKL QRAITILDTE KSFLKCMRKA
FRSGKLLQVG YTPDGKDDYR WCFRVDEVNW TTWNTNVGII NEDPGNCEGV KRTLSFSLRS
SRVSGRHWKN FALVPLLREA SARDRQSAQP EEVYLRQFSG SLKPEDAEVF KSPAASGEK*

speed

0.79 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999437233 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
known disease mutation at this position (HGMD CM163259)
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr17:3486702G>AN/A show variant in all transcripts IGV

HGNC symbol

TRPV1

Ensembl transcript ID

ENST00000576351

Genbank transcript ID

N/A

UniProt peptide

Q8NER1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.1376C>T
cDNA.1409C>T
g.13691C>T

AA changes

T459I Score: 89 explain score(s)

position(s) of altered AA
if AA alteration in CDS

459

frameshift

known variant

Reference ID: rs224534

database	homozygous (A/A)	heterozygous	allele carriers
1000G	539	815	1354
ExAC	8709	15349	24058

known disease mutation at this position, please check HGMD for details (HGMD ID CM163259)

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	-0.041	0.012
	0.5	0.003
(flanking)	1.555	0.007

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

459

mutated

not conserved

459

Ptroglodytes

all identical

ENSPTRG00000024045

437

Mmulatta

all identical

ENSMMUG00000000711

469

Fcatus

no homologue

Mmusculus

not conserved

ENSMUSG00000005952

469

Ggallus

all identical

ENSGALG00000004649

474

QKG

Trubripes

no homologue

Drerio

all conserved

ENSDARG00000059883

430

EGKDYAN

Dmelanogaster

not conserved

FBgn0036414

510

Celegans

not conserved

B0212.5

425

EDP

Xtropicalis

not conserved

ENSXETG00000005790

479

protein features

start (aa)	end (aa)	feature	details
455	476	TOPO_DOM	Extracellular (Potential).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2490 / 2490

position (AA) of stopcodon in wt / mu AA sequence

830 / 830

position of stopcodon in wt / mu cDNA

2523 / 2523

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

34 / 34

chromosome

strand

-1

last intron/exon boundary

2351

theoretical NMD boundary in CDS

2267

length of CDS

2490

coding sequence (CDS) position

1376

cDNA position
(for ins/del: last normal base / first normal base)

1409

gDNA position
(for ins/del: last normal base / first normal base)

13691

chromosomal position
(for ins/del: last normal base / first normal base)

3486702

original gDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered gDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

original cDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered cDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

wildtype AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGVL AYILQREIQE
PECRHLSRKF TEWAYGPVHS SLYDLSCIDT CEKNSVLENR HDMLLVEPLN RLLQDKWDRF
VKRIFYFNFL VYCLYMIIFT MAAYYRPVDG LPPFKMEKTG DYFRVTGEIL SVLGGVYFFF
RGIQYFLQRR PSMKTLFVDS YSEMLFFLQS LFMLATVVLY FSHLKEYVAS MVFSLALGWT
NMLYYTRGFQ QMGIYAVMIE KMILRDLCRF MFVYIVFLFG FSTAVVTLIE DGKNDSLPSE
STSHRWRGPA CRPPDSSYNS LYSTCLELFK FTIGMGDLEF TENYDFKAVF IILLLAYVIL
TYILLLNMLI ALMGETVNKI AQESKNIWKL QRAITILDTE KSFLKCMRKA FRSGKLLQVG
YTPDGKDDYR WCFRVDEVNW TTWNTNVGII NEDPGNCEGV KRTLSFSLRS SRVSGRHWKN
FALVPLLREA SARDRQSAQP EEVYLRQFSG SLKPEDAEVF KSPAASGEK*

mutated AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGVL AYILQREIQE
PECRHLSRKF TEWAYGPVHS SLYDLSCIDT CEKNSVLENR HDMLLVEPLN RLLQDKWDRF
VKRIFYFNFL VYCLYMIIFT MAAYYRPVDG LPPFKMEKIG DYFRVTGEIL SVLGGVYFFF
RGIQYFLQRR PSMKTLFVDS YSEMLFFLQS LFMLATVVLY FSHLKEYVAS MVFSLALGWT
NMLYYTRGFQ QMGIYAVMIE KMILRDLCRF MFVYIVFLFG FSTAVVTLIE DGKNDSLPSE
STSHRWRGPA CRPPDSSYNS LYSTCLELFK FTIGMGDLEF TENYDFKAVF IILLLAYVIL
TYILLLNMLI ALMGETVNKI AQESKNIWKL QRAITILDTE KSFLKCMRKA FRSGKLLQVG
YTPDGKDDYR WCFRVDEVNW TTWNTNVGII NEDPGNCEGV KRTLSFSLRS SRVSGRHWKN
FALVPLLREA SARDRQSAQP EEVYLRQFSG SLKPEDAEVF KSPAASGEK*

speed

0.32 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999437233 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
known disease mutation at this position (HGMD CM163259)
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr17:3486702G>AN/A show variant in all transcripts IGV

HGNC symbol

TRPV1

Ensembl transcript ID

ENST00000310522

Genbank transcript ID

N/A

UniProt peptide

Q8NER1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.1226C>T
cDNA.1226C>T
g.13691C>T

AA changes

T409I Score: 89 explain score(s)

position(s) of altered AA
if AA alteration in CDS

409

frameshift

known variant

Reference ID: rs224534

database	homozygous (A/A)	heterozygous	allele carriers
1000G	539	815	1354
ExAC	8709	15349	24058

known disease mutation at this position, please check HGMD for details (HGMD ID CM163259)

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	-0.041	0.012
	0.5	0.003
(flanking)	1.555	0.007

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

409

mutated

not conserved

409

Ptroglodytes

all identical

ENSPTRG00000024045

412

Mmulatta

all identical

ENSMMUG00000000711

469

Fcatus

no homologue

Mmusculus

not conserved

ENSMUSG00000005952

469

Ggallus

all identical

ENSGALG00000004649

474

QKG

Trubripes

no homologue

Drerio

all conserved

ENSDARG00000059883

430

EGKDYAN

Dmelanogaster

not conserved

FBgn0036414

510

Celegans

not conserved

B0212.5

425

EDP

Xtropicalis

not conserved

ENSXETG00000005790

479

protein features

start (aa)	end (aa)	feature	details
1	433	TOPO_DOM	Cytoplasmic (Potential).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2340 / 2340

position (AA) of stopcodon in wt / mu AA sequence

780 / 780

position of stopcodon in wt / mu cDNA

2340 / 2340

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

1 / 1

chromosome

strand

-1

last intron/exon boundary

2168

theoretical NMD boundary in CDS

2117

length of CDS

2340

coding sequence (CDS) position

1226

cDNA position
(for ins/del: last normal base / first normal base)

1226

gDNA position
(for ins/del: last normal base / first normal base)

13691

chromosomal position
(for ins/del: last normal base / first normal base)

3486702

original gDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered gDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

original cDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered cDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

wildtype AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGNR HDMLLVEPLN
RLLQDKWDRF VKRIFYFNFL VYCLYMIIFT MAAYYRPVDG LPPFKMEKTG DYFRVTGEIL
SVLGGVYFFF RGIQYFLQRR PSMKTLFVDS YSEMLFFLQS LFMLATVVLY FSHLKEYVAS
MVFSLALGWT NMLYYTRGFQ QMGIYAVMIE KMILRDLCRF MFVYIVFLFG FSTAVVTLIE
DGKNDSLPSE STSHRWRGPA CRPPDSSYNS LYSTCLELFK FTIGMGDLEF TENYDFKAVF
IILLLAYVIL TYILLLNMLI ALMGETVNKI AQESKNIWKL QRAITILDTE KSFLKCMRKA
FRSGKLLQVG YTPDGKDDYR WCFRVDEVNW TTWNTNVGII NEDPGNCEGV KRTLSFSLRS
SRVSGRHWKN FALVPLLREA SARDRQSAQP EEVYLRQFSG SLKPEDAEVF KSPAASGEK*

mutated AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGNR HDMLLVEPLN
RLLQDKWDRF VKRIFYFNFL VYCLYMIIFT MAAYYRPVDG LPPFKMEKIG DYFRVTGEIL
SVLGGVYFFF RGIQYFLQRR PSMKTLFVDS YSEMLFFLQS LFMLATVVLY FSHLKEYVAS
MVFSLALGWT NMLYYTRGFQ QMGIYAVMIE KMILRDLCRF MFVYIVFLFG FSTAVVTLIE
DGKNDSLPSE STSHRWRGPA CRPPDSSYNS LYSTCLELFK FTIGMGDLEF TENYDFKAVF
IILLLAYVIL TYILLLNMLI ALMGETVNKI AQESKNIWKL QRAITILDTE KSFLKCMRKA
FRSGKLLQVG YTPDGKDDYR WCFRVDEVNW TTWNTNVGII NEDPGNCEGV KRTLSFSLRS
SRVSGRHWKN FALVPLLREA SARDRQSAQP EEVYLRQFSG SLKPEDAEVF KSPAASGEK*

speed

0.32 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999437233 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
known disease mutation at this position (HGMD CM163259)
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr17:3486702G>AN/A show variant in all transcripts IGV

HGNC symbol

TRPV1

Ensembl transcript ID

ENST00000174621

Genbank transcript ID

N/A

UniProt peptide

Q8NER1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.1400C>T
cDNA.1690C>T
g.13691C>T

AA changes

T467I Score: 89 explain score(s)

position(s) of altered AA
if AA alteration in CDS

467

frameshift

known variant

Reference ID: rs224534

database	homozygous (A/A)	heterozygous	allele carriers
1000G	539	815	1354
ExAC	8709	15349	24058

known disease mutation at this position, please check HGMD for details (HGMD ID CM163259)

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	-0.041	0.012
	0.5	0.003
(flanking)	1.555	0.007

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

467

mutated

not conserved

467

Ptroglodytes

all identical

ENSPTRG00000024045

427

Mmulatta

all identical

ENSMMUG00000000711

469

Fcatus

no homologue

Mmusculus

not conserved

ENSMUSG00000005952

469

Ggallus

all identical

ENSGALG00000004649

474

QKG

Trubripes

no homologue

Drerio

all conserved

ENSDARG00000059883

430

EGKDYAN

Dmelanogaster

not conserved

FBgn0036414

510

Celegans

not conserved

B0212.5

425

EDP

Xtropicalis

not conserved

ENSXETG00000005790

479

protein features

start (aa)	end (aa)	feature	details
455	476	TOPO_DOM	Extracellular (Potential).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2514 / 2514

position (AA) of stopcodon in wt / mu AA sequence

838 / 838

position of stopcodon in wt / mu cDNA

2804 / 2804

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

291 / 291

chromosome

strand

-1

last intron/exon boundary

2632

theoretical NMD boundary in CDS

2291

length of CDS

2514

coding sequence (CDS) position

1400

cDNA position
(for ins/del: last normal base / first normal base)

1690

gDNA position
(for ins/del: last normal base / first normal base)

13691

chromosomal position
(for ins/del: last normal base / first normal base)

3486702

original gDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered gDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

original cDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered cDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

wildtype AA sequence

METLTPGHLQ PSPSSPRPRA APGSLGRVTR RRLSRWIALT RKVSWTPARP SQSALLSPSR
GQETAPPVPG CCPRTLSPPA PRRPSGSMIA GVSLKPLLRI TARIWRACCS SCRRARSTSQ
TTSSKVAPAL GSGRAPALAC PDPPLCLSDP ETGKTCLLKA MLNLHDGQNT TIPLLLEIAR
QTDSLKELVN ASYTDSYYKG QTALHIAIER RNMALVTLLV ENGADVQAAA HGDFFKKTKG
RPGFYFGELP LSLAACTNQL GIVKFLLQNS WQTADISARD SVGNTVLHAL VEVADNTADN
TKFVTSMYNE ILMLGAKLHP TLKLEELTNK KGMTPLALAA GTGKIGVLAY ILQREIQEPE
CRHLSRKFTE WAYGPVHSSL YDLSCIDTCE KNSVLEVIAY SSSETPNRHD MLLVEPLNRL
LQDKWDRFVK RIFYFNFLVY CLYMIIFTMA AYYRPVDGLP PFKMEKTGDY FRVTGEILSV
LGGVYFFFRG IQYFLQRRPS MKTLFVDSYS EMLFFLQSLF MLATVVLYFS HLKEYVASMV
FSLALGWTNM LYYTRGFQQM GIYAVMIEKM ILRDLCRFMF VYIVFLFGFS TAVVTLIEDG
KNDSLPSEST SHRWRGPACR PPDSSYNSLY STCLELFKFT IGMGDLEFTE NYDFKAVFII
LLLAYVILTY ILLLNMLIAL MGETVNKIAQ ESKNIWKLQR AITILDTEKS FLKCMRKAFR
SGKLLQVGYT PDGKDDYRWC FRVDEVNWTT WNTNVGIINE DPGNCEGVKR TLSFSLRSSR
VSGRHWKNFA LVPLLREASA RDRQSAQPEE VYLRQFSGSL KPEDAEVFKS PAASGEK*

mutated AA sequence

METLTPGHLQ PSPSSPRPRA APGSLGRVTR RRLSRWIALT RKVSWTPARP SQSALLSPSR
GQETAPPVPG CCPRTLSPPA PRRPSGSMIA GVSLKPLLRI TARIWRACCS SCRRARSTSQ
TTSSKVAPAL GSGRAPALAC PDPPLCLSDP ETGKTCLLKA MLNLHDGQNT TIPLLLEIAR
QTDSLKELVN ASYTDSYYKG QTALHIAIER RNMALVTLLV ENGADVQAAA HGDFFKKTKG
RPGFYFGELP LSLAACTNQL GIVKFLLQNS WQTADISARD SVGNTVLHAL VEVADNTADN
TKFVTSMYNE ILMLGAKLHP TLKLEELTNK KGMTPLALAA GTGKIGVLAY ILQREIQEPE
CRHLSRKFTE WAYGPVHSSL YDLSCIDTCE KNSVLEVIAY SSSETPNRHD MLLVEPLNRL
LQDKWDRFVK RIFYFNFLVY CLYMIIFTMA AYYRPVDGLP PFKMEKIGDY FRVTGEILSV
LGGVYFFFRG IQYFLQRRPS MKTLFVDSYS EMLFFLQSLF MLATVVLYFS HLKEYVASMV
FSLALGWTNM LYYTRGFQQM GIYAVMIEKM ILRDLCRFMF VYIVFLFGFS TAVVTLIEDG
KNDSLPSEST SHRWRGPACR PPDSSYNSLY STCLELFKFT IGMGDLEFTE NYDFKAVFII
LLLAYVILTY ILLLNMLIAL MGETVNKIAQ ESKNIWKLQR AITILDTEKS FLKCMRKAFR
SGKLLQVGYT PDGKDDYRWC FRVDEVNWTT WNTNVGIINE DPGNCEGVKR TLSFSLRSSR
VSGRHWKNFA LVPLLREASA RDRQSAQPEE VYLRQFSGSL KPEDAEVFKS PAASGEK*

speed

0.33 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.99999997259521 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
known disease mutation at this position (HGMD CM163259)
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr17:3486702G>AN/A show variant in all transcripts IGV

HGNC symbol

TRPV1

Ensembl transcript ID

ENST00000425167

Genbank transcript ID

N/A

UniProt peptide

Q8NER1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.1439C>T
cDNA.1456C>T
g.13691C>T

AA changes

T480I Score: 89 explain score(s)

position(s) of altered AA
if AA alteration in CDS

480

frameshift

known variant

Reference ID: rs224534

database	homozygous (A/A)	heterozygous	allele carriers
1000G	539	815	1354
ExAC	8709	15349	24058

known disease mutation at this position, please check HGMD for details (HGMD ID CM163259)

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	-0.041	0.012
	0.5	0.003
(flanking)	1.555	0.007

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

480

mutated

not conserved

480

Ptroglodytes

all identical

ENSPTRG00000024045

468

Mmulatta

all identical

ENSMMUG00000000711

469

Fcatus

no homologue

Mmusculus

all identical

ENSMUSG00000005952

469

Ggallus

all identical

ENSGALG00000004649

474

QKG

Trubripes

no homologue

Drerio

all conserved

ENSDARG00000059883

430

EGKDYAN

Dmelanogaster

not conserved

FBgn0036414

510

Celegans

not conserved

B0212.5

424

EDP

Xtropicalis

not conserved

ENSXETG00000005790

479

protein features

start (aa)	end (aa)	feature	details
477	497	TRANSMEM	Helical; (Potential).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2553 / 2553

position (AA) of stopcodon in wt / mu AA sequence

851 / 851

position of stopcodon in wt / mu cDNA

2570 / 2570

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

18 / 18

chromosome

strand

-1

last intron/exon boundary

2398

theoretical NMD boundary in CDS

2330

length of CDS

2553

coding sequence (CDS) position

1439

cDNA position
(for ins/del: last normal base / first normal base)

1456

gDNA position
(for ins/del: last normal base / first normal base)

13691

chromosomal position
(for ins/del: last normal base / first normal base)

3486702

original gDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered gDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

original cDNA sequence snippet

TCCCTTTAAGATGGAAAAAACTGGAGACTATTTCCGAGTTA

altered cDNA sequence snippet

TCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTA

wildtype AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGVI ENGPPLSFMV
LAYILQREIQ EPECRHLSRK FTEWAYGPVH SSLYDLSCID TCEKNSVLEV IAYSSSETPN
RHDMLLVEPL NRLLQDKWDR FVKRIFYFNF LVYCLYMIIF TMAAYYRPVD GLPPFKMEKT
GDYFRVTGEI LSVLGGVYFF FRGIQYFLQR RPSMKTLFVD SYSEMLFFLQ SLFMLATVVL
YFSHLKEYVA SMVFSLALGW TNMLYYTRGF QQMGIYAVMI EKMILRDLCR FMFVYIVFLF
GFSTAVVTLI EDGKNDSLPS ESTSHRWRGP ACRPPDSSYN SLYSTCLELF KFTIGMGDLE
FTENYDFKAV FIILLLAYVI LTYILLLNML IALMGETVNK IAQESKNIWK LQRAITILDT
EKSFLKCMRK AFRSGKLLQV GYTPDGKDDY RWCFRVDEVN WTTWNTNVGI INEDPGNCEG
VKRTLSFSLR SSRVSGRHWK NFALVPLLRE ASARDRQSAQ PEEVYLRQFS GSLKPEDAEV
FKSPAASGEK *

mutated AA sequence

MKKWSSTDLG AAADPLQKDT CPDPLDGDPN SRPPPAKPQL STAKSRTRLF GKGDSEEAFP
VDCPHEEGEL DSCPTITVSP VITIQRPGDG PTGARLLSQD SVAASTEKTL RLYDRRSIFE
AVAQNNCQDL ESLLLFLQKS KKHLTDNEFK DPETGKTCLL KAMLNLHDGQ NTTIPLLLEI
ARQTDSLKEL VNASYTDSYY KGQTALHIAI ERRNMALVTL LVENGADVQA AAHGDFFKKT
KGRPGFYFGE LPLSLAACTN QLGIVKFLLQ NSWQTADISA RDSVGNTVLH ALVEVADNTA
DNTKFVTSMY NEILMLGAKL HPTLKLEELT NKKGMTPLAL AAGTGKIGVI ENGPPLSFMV
LAYILQREIQ EPECRHLSRK FTEWAYGPVH SSLYDLSCID TCEKNSVLEV IAYSSSETPN
RHDMLLVEPL NRLLQDKWDR FVKRIFYFNF LVYCLYMIIF TMAAYYRPVD GLPPFKMEKI
GDYFRVTGEI LSVLGGVYFF FRGIQYFLQR RPSMKTLFVD SYSEMLFFLQ SLFMLATVVL
YFSHLKEYVA SMVFSLALGW TNMLYYTRGF QQMGIYAVMI EKMILRDLCR FMFVYIVFLF
GFSTAVVTLI EDGKNDSLPS ESTSHRWRGP ACRPPDSSYN SLYSTCLELF KFTIGMGDLE
FTENYDFKAV FIILLLAYVI LTYILLLNML IALMGETVNK IAQESKNIWK LQRAITILDT
EKSFLKCMRK AFRSGKLLQV GYTPDGKDDY RWCFRVDEVN WTTWNTNVGI INEDPGNCEG
VKRTLSFSLR SSRVSGRHWK NFALVPLLRE ASARDRQSAQ PEEVYLRQFS GSLKPEDAEV
FKSPAASGEK *

speed

0.32 s

Problems

data problem

No NCBI gene ID found for this transcript

back to results table