MutationTaster - study a chromosomal position

NEVER press reload or F5 - unless you want to start from the very beginning.
input seems to be ok - now mapping the variant to the different transcripts...
found 4 transcript(s)...
Querying Taster for transcript #1: ENST00000371754
Querying Taster for transcript #2: ENST00000371752
Querying Taster for transcript #3: ENST00000371744
Querying Taster for transcript #4: ENST00000396105
MT speed 0 s - this script 3.151144 s

Results

genesymbol	prediction	probability	model	prediction problem	splicing	ClinVar	amino acid changes	variant type	dbSNP ID	protein length	file
ZNFX1	polymorphism_automatic	0.113455067160512	simple_aae				Q924H	single base exchange	rs238221		show file
ZNFX1	polymorphism_automatic	0.283369210433796	simple_aae				Q924H	single base exchange	rs238221		show file
ZNFX1	polymorphism_automatic	0.283369210433796	simple_aae				Q924H	single base exchange	rs238221		show file

Taster files

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.886544932839488 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr20:47872377C>GN/A show variant in all transcripts IGV

HGNC symbol

ZNFX1

Ensembl transcript ID

ENST00000371754

Genbank transcript ID

N/A

UniProt peptide

Q9P2E3

alteration type

single base exchange

alteration region

CDS

DNA changes

c.2772G>C
cDNA.3226G>C
g.22587G>C

AA changes

Q924H Score: 24 explain score(s)

position(s) of altered AA
if AA alteration in CDS

924

frameshift

known variant

Reference ID: rs238221

database	homozygous (G/G)	heterozygous	allele carriers
1000G	814	1211	2025
ExAC	28291	-23815	4476

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	3.167	1
	0.128	0.998
(flanking)	2.504	1

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor marginally increased	22592	wt: 0.3618 / mu: 0.4402 (marginal change - not scored)	wt: GCTGGACCTCAGTTC mu: CCTGGACCTCAGTTC	TGGA\|cctc

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

924

mutated

not conserved

924

Ptroglodytes

all identical

ENSPTRG00000013603

924

Mmulatta

all identical

ENSMMUG00000023623

924

Fcatus

not conserved

ENSFCAG00000001449

925

Mmusculus

all identical

ENSMUSG00000039501

917

Ggallus

all identical

ENSGALG00000004859

840

Trubripes

not conserved

ENSTRUG00000014181

774

Drerio

not conserved

ENSDARG00000074028

868

Dmelanogaster

no alignment

FBgn0039165

n/a

Celegans

not conserved

ZK1067.2

1385

Xtropicalis

no homologue

protein features

start (aa)	end (aa)	feature	details
886	967	COILED	Potential.	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

3813 / 3813

position (AA) of stopcodon in wt / mu AA sequence

1271 / 1271

position of stopcodon in wt / mu cDNA

4267 / 4267

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

455 / 455

chromosome

strand

-1

last intron/exon boundary

3881

theoretical NMD boundary in CDS

3376

length of CDS

3813

coding sequence (CDS) position

2772

cDNA position
(for ins/del: last normal base / first normal base)

3226

gDNA position
(for ins/del: last normal base / first normal base)

22587

chromosomal position
(for ins/del: last normal base / first normal base)

47872377

original gDNA sequence snippet

GAGATCGAGGATGTTTGGCAGCTGGACCTCAGTTCTCGCTG

altered gDNA sequence snippet

GAGATCGAGGATGTTTGGCACCTGGACCTCAGTTCTCGCTG

original cDNA sequence snippet

GAGATCGAGGATGTTTGGCAGCTGGACCTCAGTTCTCGCTG

altered cDNA sequence snippet

GAGATCGAGGATGTTTGGCACCTGGACCTCAGTTCTCGCTG

wildtype AA sequence

mutated AA sequence

speed

0.76 s

All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.716630789566204 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr20:47872377C>GN/A show variant in all transcripts IGV

HGNC symbol

ZNFX1

Ensembl transcript ID

ENST00000371752

Genbank transcript ID

N/A

UniProt peptide

Q9P2E3

alteration type

single base exchange

alteration region

CDS

DNA changes

c.2772G>C
cDNA.2857G>C
g.22587G>C

AA changes

Q924H Score: 24 explain score(s)

position(s) of altered AA
if AA alteration in CDS

924

frameshift

known variant

Reference ID: rs238221

database	homozygous (G/G)	heterozygous	allele carriers
1000G	814	1211	2025
ExAC	28291	-23815	4476

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	3.167	1
	0.128	0.998
(flanking)	2.504	1

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor marginally increased	22592	wt: 0.3618 / mu: 0.4402 (marginal change - not scored)	wt: GCTGGACCTCAGTTC mu: CCTGGACCTCAGTTC	TGGA\|cctc

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

924

mutated

not conserved

924

Ptroglodytes

all identical

ENSPTRG00000013603

924

Mmulatta

all identical

ENSMMUG00000023623

924

Fcatus

no alignment

ENSFCAG00000001449

n/a

Mmusculus

all identical

ENSMUSG00000039501

917

Ggallus

all identical

ENSGALG00000004859

840

Trubripes

not conserved

ENSTRUG00000014181

774

Drerio

not conserved

ENSDARG00000074028

868

Dmelanogaster

no alignment

FBgn0039165

n/a

Celegans

not conserved

ZK1067.2

1385

Xtropicalis

no homologue

protein features

start (aa)	end (aa)	feature	details
886	967	COILED	Potential.	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

5757 / 5757

position (AA) of stopcodon in wt / mu AA sequence

1919 / 1919

position of stopcodon in wt / mu cDNA

5842 / 5842

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

86 / 86

chromosome

strand

-1

last intron/exon boundary

3398

theoretical NMD boundary in CDS

3262

length of CDS

5757

coding sequence (CDS) position

2772

cDNA position
(for ins/del: last normal base / first normal base)

2857

gDNA position
(for ins/del: last normal base / first normal base)

22587

chromosomal position
(for ins/del: last normal base / first normal base)

47872377

original gDNA sequence snippet

GAGATCGAGGATGTTTGGCAGCTGGACCTCAGTTCTCGCTG

altered gDNA sequence snippet

GAGATCGAGGATGTTTGGCACCTGGACCTCAGTTCTCGCTG

original cDNA sequence snippet

GAGATCGAGGATGTTTGGCAGCTGGACCTCAGTTCTCGCTG

altered cDNA sequence snippet

GAGATCGAGGATGTTTGGCACCTGGACCTCAGTTCTCGCTG

wildtype AA sequence

MEERRPHLDA RPRNSHTNHR GPVDGELPPR ARNQANNPPA NALRGGASHP GRHPRANNHP
AAYWQREERF RAMGRNPHQG RRNQEGHASD EARDQRHDQE NDTRWRNGNQ DCRNRRPPWS
NDNFQQWRTP HQKPTEQPQQ AKKLGYKFLE SLLQKDPSEV VITLATSLGL KELLSHSSMK
SNFLELICQV LRKACSSKMD RQSVLHVLGI LKNSKFLKVC LPAYVVGMIT EPIPDIRNQY
PEHISNIISL LQDLVSVFPA SSVQETSMLV SLLPTSLNAL RASGVDIEEE TEKNLEKVQT
IIEHLQEKRR EGTLRVDTYT LVQPEAEDHV ESYRTMPIYP TYNEVHLDER PFLRPNIISG
KYDSTAIYLD THFRLLREDF VRPLREGILE LLQSFEDQGL RKRKFDDIRI YFDTRIITPM
CSSSGIVYKV QFDTKPLKFV RWQNSKRLLY GSLVCMSKDN FETFLFATVS NREQEDLCRG
IVQLCFNEQS QQLLAEVQPS DSFLMVETTA YFEAYRHVLE GLQEVQEEDV PFQRNIVECN
SHVKEPRYLL MGGRYDFTPL IENPSATGEF LRNVEGLRHP RINVLDPGQW PSKEALKLDD
SQMEALQFAL TRELAIIQGP PGTGKTYVGL KIVQALLTNE SVWQISLQKF PILVVCYTNH
ALDQFLEGIY NCQKTSIVRV GGRSNSEILK QFTLRELRNK REFRRNLPMH LRRAYMSIMT
QMKESEQELH EGAKTLECTM RGVLREQYLQ KYISPQHWES LMNGPVQDSE WICFQHWKHS
MMLEWLGLGV GSFTQSVSPA GPENTAQAEG DEEEEGEEES SLIEIAEEAD LIQADRVIEE
EEVVRPQRRK KEESGADQEL AKMLLAMRLD HCGTGTAAGQ EQATGEWQTQ RNQKKKMKKR
VKDELRKLNT MTAAEANEIE DVWQLDLSSR WQLYRLWLQL YQADTRRKIL SYERQYRTSA
ERMAELRLQE DLHILKDAQV VGMTTTGAAK YRQILQKVEP RIVIVEEAAE VLEAHTIATL
SKACQHLILI GDHQQLRPSA NVYDLAKNFN LEVSLFERLV KVNIPFVRLN YQHRMCPEIA
RLLTPHIYQD LENHPSVLKY EKIKGVSSNL FFVEHNFPEQ EIQEGKSHQN QHEAHFVVEL
CKYFLCQEYL PSQITILTTY TGQLFCLRKL MPAKTFAGVR VHVVDKYQGE ENDIILLSLV
RSNQEGKVGF LQISNRICVA LSRAKKGMYC IGNMQMLAKV PLWSKIIHTL RENNQIGPML
RLCCQNHPET HTLVSKASDF QKVPEGGCSL PCEFRLGCGH VCTRACHPYD SSHKEFQCMK
PCQKVICQEG HRCPLVCFQE CQPCQVKVPK TIPRCGHEQM VPCSVPESDF CCQEPCSKSL
RCGHRCSHPC GEDCVQLCSE MVTIKLKCGH SQPVKCGHVE GLLYGGLLVK CTTKCGTILD
CGHPCPGSCH SCFEGRFHER CQQPCKRLLI CSHKCQEPCI GECPPCQRTC QNRCVHSQCK
KKCGELCSPC VEPCVWRCQH YQCTKLCSEP CNRPPCYVPC TKLLVCGHPC IGLCGEPCPK
KCRICHMDEV TQIFFGFEDE PDARFVQLED CSHIFEVQAL DRYMNEQKDD EVAIRLKVCP
ICQVPIRKNL RYGTSIKQRL EEIEIIKEKI QGSAGEIATS QERLKALLER KSLLHQLLPE
DFLMLKEKLA QKNLSVKDLG LVENYISFYD HLASLWDSLK KMHVLEEKRV RTRLEQVHEW
LAKKRLSFTS QELSDLRSEI QRLTYLVNLL TRYKIAEKKV KDSIAVEVYS VQNILEKTCK
FTQEDEQLVQ EKMEALKATL PCSGLGISEE ERVQIVSAIG YPRGHWFKCR NGHIYVIGDC
GGAMERGTCP DCKEVIGGTN HTLERSNQLA SEMDGAQHAA WSDTANNLMN FEEIQGMM*

mutated AA sequence

MEERRPHLDA RPRNSHTNHR GPVDGELPPR ARNQANNPPA NALRGGASHP GRHPRANNHP
AAYWQREERF RAMGRNPHQG RRNQEGHASD EARDQRHDQE NDTRWRNGNQ DCRNRRPPWS
NDNFQQWRTP HQKPTEQPQQ AKKLGYKFLE SLLQKDPSEV VITLATSLGL KELLSHSSMK
SNFLELICQV LRKACSSKMD RQSVLHVLGI LKNSKFLKVC LPAYVVGMIT EPIPDIRNQY
PEHISNIISL LQDLVSVFPA SSVQETSMLV SLLPTSLNAL RASGVDIEEE TEKNLEKVQT
IIEHLQEKRR EGTLRVDTYT LVQPEAEDHV ESYRTMPIYP TYNEVHLDER PFLRPNIISG
KYDSTAIYLD THFRLLREDF VRPLREGILE LLQSFEDQGL RKRKFDDIRI YFDTRIITPM
CSSSGIVYKV QFDTKPLKFV RWQNSKRLLY GSLVCMSKDN FETFLFATVS NREQEDLCRG
IVQLCFNEQS QQLLAEVQPS DSFLMVETTA YFEAYRHVLE GLQEVQEEDV PFQRNIVECN
SHVKEPRYLL MGGRYDFTPL IENPSATGEF LRNVEGLRHP RINVLDPGQW PSKEALKLDD
SQMEALQFAL TRELAIIQGP PGTGKTYVGL KIVQALLTNE SVWQISLQKF PILVVCYTNH
ALDQFLEGIY NCQKTSIVRV GGRSNSEILK QFTLRELRNK REFRRNLPMH LRRAYMSIMT
QMKESEQELH EGAKTLECTM RGVLREQYLQ KYISPQHWES LMNGPVQDSE WICFQHWKHS
MMLEWLGLGV GSFTQSVSPA GPENTAQAEG DEEEEGEEES SLIEIAEEAD LIQADRVIEE
EEVVRPQRRK KEESGADQEL AKMLLAMRLD HCGTGTAAGQ EQATGEWQTQ RNQKKKMKKR
VKDELRKLNT MTAAEANEIE DVWHLDLSSR WQLYRLWLQL YQADTRRKIL SYERQYRTSA
ERMAELRLQE DLHILKDAQV VGMTTTGAAK YRQILQKVEP RIVIVEEAAE VLEAHTIATL
SKACQHLILI GDHQQLRPSA NVYDLAKNFN LEVSLFERLV KVNIPFVRLN YQHRMCPEIA
RLLTPHIYQD LENHPSVLKY EKIKGVSSNL FFVEHNFPEQ EIQEGKSHQN QHEAHFVVEL
CKYFLCQEYL PSQITILTTY TGQLFCLRKL MPAKTFAGVR VHVVDKYQGE ENDIILLSLV
RSNQEGKVGF LQISNRICVA LSRAKKGMYC IGNMQMLAKV PLWSKIIHTL RENNQIGPML
RLCCQNHPET HTLVSKASDF QKVPEGGCSL PCEFRLGCGH VCTRACHPYD SSHKEFQCMK
PCQKVICQEG HRCPLVCFQE CQPCQVKVPK TIPRCGHEQM VPCSVPESDF CCQEPCSKSL
RCGHRCSHPC GEDCVQLCSE MVTIKLKCGH SQPVKCGHVE GLLYGGLLVK CTTKCGTILD
CGHPCPGSCH SCFEGRFHER CQQPCKRLLI CSHKCQEPCI GECPPCQRTC QNRCVHSQCK
KKCGELCSPC VEPCVWRCQH YQCTKLCSEP CNRPPCYVPC TKLLVCGHPC IGLCGEPCPK
KCRICHMDEV TQIFFGFEDE PDARFVQLED CSHIFEVQAL DRYMNEQKDD EVAIRLKVCP
ICQVPIRKNL RYGTSIKQRL EEIEIIKEKI QGSAGEIATS QERLKALLER KSLLHQLLPE
DFLMLKEKLA QKNLSVKDLG LVENYISFYD HLASLWDSLK KMHVLEEKRV RTRLEQVHEW
LAKKRLSFTS QELSDLRSEI QRLTYLVNLL TRYKIAEKKV KDSIAVEVYS VQNILEKTCK
FTQEDEQLVQ EKMEALKATL PCSGLGISEE ERVQIVSAIG YPRGHWFKCR NGHIYVIGDC
GGAMERGTCP DCKEVIGGTN HTLERSNQLA SEMDGAQHAA WSDTANNLMN FEEIQGMM*

speed

0.45 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.716630789566204 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr20:47872377C>GN/A show variant in all transcripts IGV

HGNC symbol

ZNFX1

Ensembl transcript ID

ENST00000396105

Genbank transcript ID

NM_021035

UniProt peptide

Q9P2E3

alteration type

single base exchange

alteration region

CDS

DNA changes

c.2772G>C
cDNA.3019G>C
g.22587G>C

AA changes

Q924H Score: 24 explain score(s)

position(s) of altered AA
if AA alteration in CDS

924

frameshift

known variant

Reference ID: rs238221

database	homozygous (G/G)	heterozygous	allele carriers
1000G	814	1211	2025
ExAC	28291	-23815	4476

regulatory features

H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	3.167	1
	0.128	0.998
(flanking)	2.504	1

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor marginally increased	22592	wt: 0.3618 / mu: 0.4402 (marginal change - not scored)	wt: GCTGGACCTCAGTTC mu: CCTGGACCTCAGTTC	TGGA\|cctc

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

924

mutated

not conserved

924

Ptroglodytes

all identical

ENSPTRG00000013603

924

Mmulatta

all identical

ENSMMUG00000023623

924

Fcatus

no alignment

ENSFCAG00000001449

n/a

Mmusculus

all identical

ENSMUSG00000039501

917

Ggallus

all identical

ENSGALG00000004859

840

Trubripes

not conserved

ENSTRUG00000014181

774

Drerio

not conserved

ENSDARG00000074028

868

Dmelanogaster

no alignment

FBgn0039165

n/a

Celegans

not conserved

ZK1067.2

1385

Xtropicalis

no homologue

protein features

start (aa)	end (aa)	feature	details
886	967	COILED	Potential.	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

5757 / 5757

position (AA) of stopcodon in wt / mu AA sequence

1919 / 1919

position of stopcodon in wt / mu cDNA

6004 / 6004

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

248 / 248

chromosome

strand

-1

last intron/exon boundary

3560

theoretical NMD boundary in CDS

3262

length of CDS

5757

coding sequence (CDS) position

2772

cDNA position
(for ins/del: last normal base / first normal base)

3019

gDNA position
(for ins/del: last normal base / first normal base)

22587

chromosomal position
(for ins/del: last normal base / first normal base)

47872377

original gDNA sequence snippet

GAGATCGAGGATGTTTGGCAGCTGGACCTCAGTTCTCGCTG

altered gDNA sequence snippet

GAGATCGAGGATGTTTGGCACCTGGACCTCAGTTCTCGCTG

original cDNA sequence snippet

GAGATCGAGGATGTTTGGCAGCTGGACCTCAGTTCTCGCTG

altered cDNA sequence snippet

GAGATCGAGGATGTTTGGCACCTGGACCTCAGTTCTCGCTG

wildtype AA sequence

mutated AA sequence

MEERRPHLDA RPRNSHTNHR GPVDGELPPR ARNQANNPPA NALRGGASHP GRHPRANNHP
AAYWQREERF RAMGRNPHQG RRNQEGHASD EARDQRHDQE NDTRWRNGNQ DCRNRRPPWS
NDNFQQWRTP HQKPTEQPQQ AKKLGYKFLE SLLQKDPSEV VITLATSLGL KELLSHSSMK
SNFLELICQV LRKACSSKMD RQSVLHVLGI LKNSKFLKVC LPAYVVGMIT EPIPDIRNQY
PEHISNIISL LQDLVSVFPA SSVQETSMLV SLLPTSLNAL RASGVDIEEE TEKNLEKVQT
IIEHLQEKRR EGTLRVDTYT LVQPEAEDHV ESYRTMPIYP TYNEVHLDER PFLRPNIISG
KYDSTAIYLD THFRLLREDF VRPLREGILE LLQSFEDQGL RKRKFDDIRI YFDTRIITPM
CSSSGIVYKV QFDTKPLKFV RWQNSKRLLY GSLVCMSKDN FETFLFATVS NREQEDLCRG
IVQLCFNEQS QQLLAEVQPS DSFLMVETTA YFEAYRHVLE GLQEVQEEDV PFQRNIVECN
SHVKEPRYLL MGGRYDFTPL IENPSATGEF LRNVEGLRHP RINVLDPGQW PSKEALKLDD
SQMEALQFAL TRELAIIQGP PGTGKTYVGL KIVQALLTNE SVWQISLQKF PILVVCYTNH
ALDQFLEGIY NCQKTSIVRV GGRSNSEILK QFTLRELRNK REFRRNLPMH LRRAYMSIMT
QMKESEQELH EGAKTLECTM RGVLREQYLQ KYISPQHWES LMNGPVQDSE WICFQHWKHS
MMLEWLGLGV GSFTQSVSPA GPENTAQAEG DEEEEGEEES SLIEIAEEAD LIQADRVIEE
EEVVRPQRRK KEESGADQEL AKMLLAMRLD HCGTGTAAGQ EQATGEWQTQ RNQKKKMKKR
VKDELRKLNT MTAAEANEIE DVWHLDLSSR WQLYRLWLQL YQADTRRKIL SYERQYRTSA
ERMAELRLQE DLHILKDAQV VGMTTTGAAK YRQILQKVEP RIVIVEEAAE VLEAHTIATL
SKACQHLILI GDHQQLRPSA NVYDLAKNFN LEVSLFERLV KVNIPFVRLN YQHRMCPEIA
RLLTPHIYQD LENHPSVLKY EKIKGVSSNL FFVEHNFPEQ EIQEGKSHQN QHEAHFVVEL
CKYFLCQEYL PSQITILTTY TGQLFCLRKL MPAKTFAGVR VHVVDKYQGE ENDIILLSLV
RSNQEGKVGF LQISNRICVA LSRAKKGMYC IGNMQMLAKV PLWSKIIHTL RENNQIGPML
RLCCQNHPET HTLVSKASDF QKVPEGGCSL PCEFRLGCGH VCTRACHPYD SSHKEFQCMK
PCQKVICQEG HRCPLVCFQE CQPCQVKVPK TIPRCGHEQM VPCSVPESDF CCQEPCSKSL
RCGHRCSHPC GEDCVQLCSE MVTIKLKCGH SQPVKCGHVE GLLYGGLLVK CTTKCGTILD
CGHPCPGSCH SCFEGRFHER CQQPCKRLLI CSHKCQEPCI GECPPCQRTC QNRCVHSQCK
KKCGELCSPC VEPCVWRCQH YQCTKLCSEP CNRPPCYVPC TKLLVCGHPC IGLCGEPCPK
KCRICHMDEV TQIFFGFEDE PDARFVQLED CSHIFEVQAL DRYMNEQKDD EVAIRLKVCP
ICQVPIRKNL RYGTSIKQRL EEIEIIKEKI QGSAGEIATS QERLKALLER KSLLHQLLPE
DFLMLKEKLA QKNLSVKDLG LVENYISFYD HLASLWDSLK KMHVLEEKRV RTRLEQVHEW
LAKKRLSFTS QELSDLRSEI QRLTYLVNLL TRYKIAEKKV KDSIAVEVYS VQNILEKTCK
FTQEDEQLVQ EKMEALKATL PCSGLGISEE ERVQIVSAIG YPRGHWFKCR NGHIYVIGDC
GGAMERGTCP DCKEVIGGTN HTLERSNQLA SEMDGAQHAA WSDTANNLMN FEEIQGMM*

speed

0.37 s

Problems

annotation problem

The chosen transcript ENST00000371744 on chromosome 20 has no correct in-frame stop codon (TGA, TAA or TAG) annotated
This is likely to cause a false prediction. You should choose another transcript.

back to results table