Yum, tasty mutations...

MutationTaster - study a chromosomal position

 MTQE documentation
NEVER press reload or F5 - unless you want to start from the very beginning.
input seems to be ok - now mapping the variant to the different transcripts...
found 3 transcript(s)...
Querying Taster for transcript #1: ENST00000397224
Querying Taster for transcript #2: ENST00000216187
Querying Taster for transcript #3: ENST00000397223
MT speed 0 s - this script 4.714828 s

Results

genesymbolpredictionprobabilitymodelprediction
problem		splicingClinVaramino acid changesvariant typedbSNP IDprotein lengthfile
FOXRED2polymorphism_automatic2.96640101371537e-09simple_aaeaffectedF179Lsingle base exchangers760718show file
FOXRED2polymorphism_automatic2.96640101371537e-09simple_aaeaffectedF179Lsingle base exchangers760718show file
FOXRED2polymorphism_automatic2.96640101371537e-09simple_aaeaffectedF179Lsingle base exchangers760718show file

Taster files

Yum, tasty mutations...

mutation t@sting

 documentation

Prediction

polymorphism

 Model: simple_aae, prob: 0.999999997033599 (classification due to TGP/ExAC, real probability is shown anyway)      (explain)
Summary
  • amino acid sequence changed
  • homozygous in TGP or ExAC
  • protein features (might be) affected
  • splice site changes
 hyperlink
analysed issue analysis result
name of alteration no title
alteration (phys. location) chr22:36900806A>GN/A show variant in all transcripts   IGV
HGNC symbol FOXRED2
Ensembl transcript ID ENST00000397224
Genbank transcript ID NM_001102371
UniProt peptide Q8IWF2
alteration type single base exchange
alteration region CDS
DNA changes c.535T>C
cDNA.629T>C
g.2343T>C
AA changes F179L Score: 22 explain score(s)
position(s) of altered AA
if AA alteration in CDS		 179
frameshift no
known variant Reference ID: rs760718
databasehomozygous (G/G)heterozygousallele carriers
1000G59410881682
ExAC22890-130139877
regulatory features H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation
phyloP / phastCons
PhyloPPhastCons
(flanking)4.8040.398
0.3140.181
(flanking)-0.5150.145
explain score(s) and/or inspect your position(s) in in UCSC Genome Browser
splice sites
effectgDNA positionscorewt detection sequence exon-intron border
Acc marginally increased2335wt: 0.6834 / mu: 0.7199 (marginal change - not scored)wt: TTCCTCTGTCCCCGCCTGCAGCGTCCTCTTTGTAGCCACTG
mu: TTCCTCTGTCCCCGCCTGCAGCGTCCTCCTTGTAGCCACTG		 gcag|CGTC
Donor increased2348wt: 0.29 / mu: 0.48wt: TTTGTAGCCACTGGT
mu: CTTGTAGCCACTGGT		 TGTA|gcca
distance from splice site 8
Kozak consensus sequence altered? N/A
conservation
protein level for non-synonymous changes
speciesmatchgeneaaalignment
Human      179QKGQVHQCSVLFVATGLSVPNQVD
mutated  not conserved    179QKGQVHQCSVLLVATGLSVPNQV
Ptroglodytes  not conserved  ENSPTRG00000014312  179QKGQVHQCSVLLVATGLSVPNQV
Mmulatta  no homologue    
Fcatus  not conserved  ENSFCAG00000001128  179QMGHAHRCSVLLVATGLSVPNQV
Mmusculus  not conserved  ENSMUSG00000016552  170QKGQVYQCSVLLVATGLAVPKLV
Ggallus  not conserved  ENSGALG00000012530  173QNRQSYKCSCLLVATGTWVPNVV
Trubripes  not conserved  ENSTRUG00000007543  182QHASEYKCRVLLVATGLWVPNKI
Drerio  not conserved  ENSDARG00000061354  182QNGVNYQCRVLLVSTGLWVPQEV
Dmelanogaster  no homologue    
Celegans  no homologue    
Xtropicalis  not conserved  ENSXETG00000000247  5CSVLLVASGLSLPNLV
protein features
start (aa)end (aa)featuredetails 
345345CONFLICTF -> S (in Ref. 2; BAB15610).might get lost (downstream of altered splice site)
607607CONFLICTT -> A (in Ref. 2; BAB15227).might get lost (downstream of altered splice site)
681684MOTIFPrevents secretion from ER (Potential).might get lost (downstream of altered splice site)
length of protein normal
AA sequence altered yes
position of stopcodon in wt / mu CDS 2055 / 2055
position (AA) of stopcodon in wt / mu AA sequence 685 / 685
position of stopcodon in wt / mu cDNA 2149 / 2149
poly(A) signal N/A
conservation
nucleotide level for all changes - no scoring up to now		 N/A
position of start ATG in wt / mu cDNA 95 / 95
chromosome 22
strand -1
last intron/exon boundary 1890
theoretical NMD boundary in CDS 1745
length of CDS 2055
coding sequence (CDS) position 535
cDNA position
(for ins/del: last normal base / first normal base)		 629
gDNA position
(for ins/del: last normal base / first normal base)		 2343
chromosomal position
(for ins/del: last normal base / first normal base)		 36900806
original gDNA sequence snippet TCCCCGCCTGCAGCGTCCTCTTTGTAGCCACTGGTTTATCA
altered gDNA sequence snippet TCCCCGCCTGCAGCGTCCTCCTTGTAGCCACTGGTTTATCA
original cDNA sequence snippet TGCATCAGTGCAGCGTCCTCTTTGTAGCCACTGGTTTATCA
altered cDNA sequence snippet TGCATCAGTGCAGCGTCCTCCTTGTAGCCACTGGTTTATCA
wildtype AA sequence MGLSAAAPLW GPPGLLLAIA LHPALSVPPR RDYCVLGAGP AGLQMAYFLQ RAGRDYAVFE
RAPRPGSFFT RYPRHRKLIS INKRYTGKAN AEFNLRHDWN SLLSHDPRLL FRHYSRAYFP
DARDMVRYLG DFADTLGLRV QYNTTIAHVT LDKDRQAWNG HYFILTDQKG QVHQCSVLFV
ATGLSVPNQV DFPGSEYAEG YESVSVDPED FVGQNVLILG RGNSAFETAE NILGVTNFIH
MLSRSRVRLS WATHYVGDLR AINNGLLDTY QLKSLDGLLE SDLTDLAILK DSKGKFHVTP
KFFLEEANTN QSADSITLPQ DDNDNFAMRV PYDRVIRCLG WNFDFSIFNK SLRLNSGNAF
GKKYPLIRAS YESKGSRGLF ILGTASHSVD YRKSAGGFIH GFRYTVRAVH RLLEHRHHSV
TWPATELPIT QLTSSIVRRV NEASGLYQMF GVLADVILLK ENSTAFEYLE EFPIQMLAQL
ETLTGRKAKH GLFVINMEYG RNFSGPDKDV FFDDRSVGHT EDAWQSNFLH PVIYYYRYLP
TEQEVRFRPA HWPLPRPTAI HHIVEDFLTD WTAPIGHILP LRRFLENCLD TDLRSFYAES
CFLFALTRQK LPPFCQQGYL RMQGLVSTES LWQHRVESRL LRDYAPTGRR LEDSSQQLGD
QEPLGSPLAP GPLAQSVDSN KEEL*
mutated AA sequence MGLSAAAPLW GPPGLLLAIA LHPALSVPPR RDYCVLGAGP AGLQMAYFLQ RAGRDYAVFE
RAPRPGSFFT RYPRHRKLIS INKRYTGKAN AEFNLRHDWN SLLSHDPRLL FRHYSRAYFP
DARDMVRYLG DFADTLGLRV QYNTTIAHVT LDKDRQAWNG HYFILTDQKG QVHQCSVLLV
ATGLSVPNQV DFPGSEYAEG YESVSVDPED FVGQNVLILG RGNSAFETAE NILGVTNFIH
MLSRSRVRLS WATHYVGDLR AINNGLLDTY QLKSLDGLLE SDLTDLAILK DSKGKFHVTP
KFFLEEANTN QSADSITLPQ DDNDNFAMRV PYDRVIRCLG WNFDFSIFNK SLRLNSGNAF
GKKYPLIRAS YESKGSRGLF ILGTASHSVD YRKSAGGFIH GFRYTVRAVH RLLEHRHHSV
TWPATELPIT QLTSSIVRRV NEASGLYQMF GVLADVILLK ENSTAFEYLE EFPIQMLAQL
ETLTGRKAKH GLFVINMEYG RNFSGPDKDV FFDDRSVGHT EDAWQSNFLH PVIYYYRYLP
TEQEVRFRPA HWPLPRPTAI HHIVEDFLTD WTAPIGHILP LRRFLENCLD TDLRSFYAES
CFLFALTRQK LPPFCQQGYL RMQGLVSTES LWQHRVESRL LRDYAPTGRR LEDSSQQLGD
QEPLGSPLAP GPLAQSVDSN KEEL*
speed 1.27 s
All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table
Yum, tasty mutations...

mutation t@sting

 documentation

Prediction

polymorphism

 Model: simple_aae, prob: 0.999999997033599 (classification due to TGP/ExAC, real probability is shown anyway)      (explain)
Summary
  • amino acid sequence changed
  • homozygous in TGP or ExAC
  • protein features (might be) affected
  • splice site changes
 hyperlink
analysed issue analysis result
name of alteration no title
alteration (phys. location) chr22:36900806A>GN/A show variant in all transcripts   IGV
HGNC symbol FOXRED2
Ensembl transcript ID ENST00000216187
Genbank transcript ID N/A
UniProt peptide Q8IWF2
alteration type single base exchange
alteration region CDS
DNA changes c.535T>C
cDNA.647T>C
g.2343T>C
AA changes F179L Score: 22 explain score(s)
position(s) of altered AA
if AA alteration in CDS		 179
frameshift no
known variant Reference ID: rs760718
databasehomozygous (G/G)heterozygousallele carriers
1000G59410881682
ExAC22890-130139877
regulatory features H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation
phyloP / phastCons
PhyloPPhastCons
(flanking)4.8040.398
0.3140.181
(flanking)-0.5150.145
explain score(s) and/or inspect your position(s) in in UCSC Genome Browser
splice sites
effectgDNA positionscorewt detection sequence exon-intron border
Acc marginally increased2335wt: 0.6834 / mu: 0.7199 (marginal change - not scored)wt: TTCCTCTGTCCCCGCCTGCAGCGTCCTCTTTGTAGCCACTG
mu: TTCCTCTGTCCCCGCCTGCAGCGTCCTCCTTGTAGCCACTG		 gcag|CGTC
Donor increased2348wt: 0.29 / mu: 0.48wt: TTTGTAGCCACTGGT
mu: CTTGTAGCCACTGGT		 TGTA|gcca
distance from splice site 8
Kozak consensus sequence altered? N/A
conservation
protein level for non-synonymous changes
speciesmatchgeneaaalignment
Human      179QKGQVHQCSVLFVATGLSVPNQVD
mutated  not conserved    179QKGQVHQCSVLLVATGLSVPNQV
Ptroglodytes  not conserved  ENSPTRG00000014312  179QKGQVHQCSVLLVATGLSVPNQV
Mmulatta  no homologue    
Fcatus  not conserved  ENSFCAG00000001128  179QMGHAHRCSVLLVATGLSVPNQV
Mmusculus  not conserved  ENSMUSG00000016552  170QKGQVYQCSVLLVATGLAVPKLV
Ggallus  not conserved  ENSGALG00000012530  173QNRQSYKCSCLLVATGTWVPNVV
Trubripes  not conserved  ENSTRUG00000007543  182QHASEYKCRVLLVATGLWVPNKI
Drerio  not conserved  ENSDARG00000061354  182QNGVNYQCRVLLVSTGLWVPQEV
Dmelanogaster  no homologue    
Celegans  no homologue    
Xtropicalis  not conserved  ENSXETG00000000247  5CSVLLVASGLSLPNLV
protein features
start (aa)end (aa)featuredetails 
345345CONFLICTF -> S (in Ref. 2; BAB15610).might get lost (downstream of altered splice site)
607607CONFLICTT -> A (in Ref. 2; BAB15227).might get lost (downstream of altered splice site)
681684MOTIFPrevents secretion from ER (Potential).might get lost (downstream of altered splice site)
length of protein normal
AA sequence altered yes
position of stopcodon in wt / mu CDS 2055 / 2055
position (AA) of stopcodon in wt / mu AA sequence 685 / 685
position of stopcodon in wt / mu cDNA 2167 / 2167
poly(A) signal N/A
conservation
nucleotide level for all changes - no scoring up to now		 N/A
position of start ATG in wt / mu cDNA 113 / 113
chromosome 22
strand -1
last intron/exon boundary 1908
theoretical NMD boundary in CDS 1745
length of CDS 2055
coding sequence (CDS) position 535
cDNA position
(for ins/del: last normal base / first normal base)		 647
gDNA position
(for ins/del: last normal base / first normal base)		 2343
chromosomal position
(for ins/del: last normal base / first normal base)		 36900806
original gDNA sequence snippet TCCCCGCCTGCAGCGTCCTCTTTGTAGCCACTGGTTTATCA
altered gDNA sequence snippet TCCCCGCCTGCAGCGTCCTCCTTGTAGCCACTGGTTTATCA
original cDNA sequence snippet TGCATCAGTGCAGCGTCCTCTTTGTAGCCACTGGTTTATCA
altered cDNA sequence snippet TGCATCAGTGCAGCGTCCTCCTTGTAGCCACTGGTTTATCA
wildtype AA sequence MGLSAAAPLW GPPGLLLAIA LHPALSVPPR RDYCVLGAGP AGLQMAYFLQ RAGRDYAVFE
RAPRPGSFFT RYPRHRKLIS INKRYTGKAN AEFNLRHDWN SLLSHDPRLL FRHYSRAYFP
DARDMVRYLG DFADTLGLRV QYNTTIAHVT LDKDRQAWNG HYFILTDQKG QVHQCSVLFV
ATGLSVPNQV DFPGSEYAEG YESVSVDPED FVGQNVLILG RGNSAFETAE NILGVTNFIH
MLSRSRVRLS WATHYVGDLR AINNGLLDTY QLKSLDGLLE SDLTDLAILK DSKGKFHVTP
KFFLEEANTN QSADSITLPQ DDNDNFAMRV PYDRVIRCLG WNFDFSIFNK SLRLNSGNAF
GKKYPLIRAS YESKGSRGLF ILGTASHSVD YRKSAGGFIH GFRYTVRAVH RLLEHRHHSV
TWPATELPIT QLTSSIVRRV NEASGLYQMF GVLADVILLK ENSTAFEYLE EFPIQMLAQL
ETLTGRKAKH GLFVINMEYG RNFSGPDKDV FFDDRSVGHT EDAWQSNFLH PVIYYYRYLP
TEQEVRFRPA HWPLPRPTAI HHIVEDFLTD WTAPIGHILP LRRFLENCLD TDLRSFYAES
CFLFALTRQK LPPFCQQGYL RMQGLVSTES LWQHRVESRL LRDYAPTGRR LEDSSQQLGD
QEPLGSPLAP GPLAQSVDSN KEEL*
mutated AA sequence MGLSAAAPLW GPPGLLLAIA LHPALSVPPR RDYCVLGAGP AGLQMAYFLQ RAGRDYAVFE
RAPRPGSFFT RYPRHRKLIS INKRYTGKAN AEFNLRHDWN SLLSHDPRLL FRHYSRAYFP
DARDMVRYLG DFADTLGLRV QYNTTIAHVT LDKDRQAWNG HYFILTDQKG QVHQCSVLLV
ATGLSVPNQV DFPGSEYAEG YESVSVDPED FVGQNVLILG RGNSAFETAE NILGVTNFIH
MLSRSRVRLS WATHYVGDLR AINNGLLDTY QLKSLDGLLE SDLTDLAILK DSKGKFHVTP
KFFLEEANTN QSADSITLPQ DDNDNFAMRV PYDRVIRCLG WNFDFSIFNK SLRLNSGNAF
GKKYPLIRAS YESKGSRGLF ILGTASHSVD YRKSAGGFIH GFRYTVRAVH RLLEHRHHSV
TWPATELPIT QLTSSIVRRV NEASGLYQMF GVLADVILLK ENSTAFEYLE EFPIQMLAQL
ETLTGRKAKH GLFVINMEYG RNFSGPDKDV FFDDRSVGHT EDAWQSNFLH PVIYYYRYLP
TEQEVRFRPA HWPLPRPTAI HHIVEDFLTD WTAPIGHILP LRRFLENCLD TDLRSFYAES
CFLFALTRQK LPPFCQQGYL RMQGLVSTES LWQHRVESRL LRDYAPTGRR LEDSSQQLGD
QEPLGSPLAP GPLAQSVDSN KEEL*
speed 1.30 s
All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table
Yum, tasty mutations...

mutation t@sting

 documentation

Prediction

polymorphism

 Model: simple_aae, prob: 0.999999997033599 (classification due to TGP/ExAC, real probability is shown anyway)      (explain)
Summary
  • amino acid sequence changed
  • homozygous in TGP or ExAC
  • protein features (might be) affected
  • splice site changes
 hyperlink
analysed issue analysis result
name of alteration no title
alteration (phys. location) chr22:36900806A>GN/A show variant in all transcripts   IGV
HGNC symbol FOXRED2
Ensembl transcript ID ENST00000397223
Genbank transcript ID N/A
UniProt peptide Q8IWF2
alteration type single base exchange
alteration region CDS
DNA changes c.535T>C
cDNA.643T>C
g.2343T>C
AA changes F179L Score: 22 explain score(s)
position(s) of altered AA
if AA alteration in CDS		 179
frameshift no
known variant Reference ID: rs760718
databasehomozygous (G/G)heterozygousallele carriers
1000G59410881682
ExAC22890-130139877
regulatory features H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation
phyloP / phastCons
PhyloPPhastCons
(flanking)4.8040.398
0.3140.181
(flanking)-0.5150.145
explain score(s) and/or inspect your position(s) in in UCSC Genome Browser
splice sites
effectgDNA positionscorewt detection sequence exon-intron border
Acc marginally increased2335wt: 0.6834 / mu: 0.7199 (marginal change - not scored)wt: TTCCTCTGTCCCCGCCTGCAGCGTCCTCTTTGTAGCCACTG
mu: TTCCTCTGTCCCCGCCTGCAGCGTCCTCCTTGTAGCCACTG		 gcag|CGTC
Donor increased2348wt: 0.29 / mu: 0.48wt: TTTGTAGCCACTGGT
mu: CTTGTAGCCACTGGT		 TGTA|gcca
distance from splice site 8
Kozak consensus sequence altered? N/A
conservation
protein level for non-synonymous changes
speciesmatchgeneaaalignment
Human      179QKGQVHQCSVLFVATGLSVPNQVD
mutated  not conserved    179QKGQVHQCSVLLVATGLSVPNQV
Ptroglodytes  not conserved  ENSPTRG00000014312  179QKGQVHQCSVLLVATGLSVPNQV
Mmulatta  no homologue    
Fcatus  not conserved  ENSFCAG00000001128  179QMGHAHRCSVLLVATGLSVPNQV
Mmusculus  not conserved  ENSMUSG00000016552  170QKGQVYQCSVLLVATGLAVPKLV
Ggallus  not conserved  ENSGALG00000012530  173QNRQSYKCSCLLVATGTWVPNVV
Trubripes  not conserved  ENSTRUG00000007543  182QHASEYKCRVLLVATGLWVPNKI
Drerio  not conserved  ENSDARG00000061354  182QNGVNYQCRVLLVSTGLWVPQEV
Dmelanogaster  no homologue    
Celegans  no homologue    
Xtropicalis  not conserved  ENSXETG00000000247  5CSVLLVASGLSLPNLV
protein features
start (aa)end (aa)featuredetails 
345345CONFLICTF -> S (in Ref. 2; BAB15610).might get lost (downstream of altered splice site)
607607CONFLICTT -> A (in Ref. 2; BAB15227).might get lost (downstream of altered splice site)
681684MOTIFPrevents secretion from ER (Potential).might get lost (downstream of altered splice site)
length of protein normal
AA sequence altered yes
position of stopcodon in wt / mu CDS 2055 / 2055
position (AA) of stopcodon in wt / mu AA sequence 685 / 685
position of stopcodon in wt / mu cDNA 2163 / 2163
poly(A) signal N/A
conservation
nucleotide level for all changes - no scoring up to now		 N/A
position of start ATG in wt / mu cDNA 109 / 109
chromosome 22
strand -1
last intron/exon boundary 1904
theoretical NMD boundary in CDS 1745
length of CDS 2055
coding sequence (CDS) position 535
cDNA position
(for ins/del: last normal base / first normal base)		 643
gDNA position
(for ins/del: last normal base / first normal base)		 2343
chromosomal position
(for ins/del: last normal base / first normal base)		 36900806
original gDNA sequence snippet TCCCCGCCTGCAGCGTCCTCTTTGTAGCCACTGGTTTATCA
altered gDNA sequence snippet TCCCCGCCTGCAGCGTCCTCCTTGTAGCCACTGGTTTATCA
original cDNA sequence snippet TGCATCAGTGCAGCGTCCTCTTTGTAGCCACTGGTTTATCA
altered cDNA sequence snippet TGCATCAGTGCAGCGTCCTCCTTGTAGCCACTGGTTTATCA
wildtype AA sequence MGLSAAAPLW GPPGLLLAIA LHPALSVPPR RDYCVLGAGP AGLQMAYFLQ RAGRDYAVFE
RAPRPGSFFT RYPRHRKLIS INKRYTGKAN AEFNLRHDWN SLLSHDPRLL FRHYSRAYFP
DARDMVRYLG DFADTLGLRV QYNTTIAHVT LDKDRQAWNG HYFILTDQKG QVHQCSVLFV
ATGLSVPNQV DFPGSEYAEG YESVSVDPED FVGQNVLILG RGNSAFETAE NILGVTNFIH
MLSRSRVRLS WATHYVGDLR AINNGLLDTY QLKSLDGLLE SDLTDLAILK DSKGKFHVTP
KFFLEEANTN QSADSITLPQ DDNDNFAMRV PYDRVIRCLG WNFDFSIFNK SLRLNSGNAF
GKKYPLIRAS YESKGSRGLF ILGTASHSVD YRKSAGGFIH GFRYTVRAVH RLLEHRHHSV
TWPATELPIT QLTSSIVRRV NEASGLYQMF GVLADVILLK ENSTAFEYLE EFPIQMLAQL
ETLTGRKAKH GLFVINMEYG RNFSGPDKDV FFDDRSVGHT EDAWQSNFLH PVIYYYRYLP
TEQEVRFRPA HWPLPRPTAI HHIVEDFLTD WTAPIGHILP LRRFLENCLD TDLRSFYAES
CFLFALTRQK LPPFCQQGYL RMQGLVSTES LWQHRVESRL LRDYAPTGRR LEDSSQQLGD
QEPLGSPLAP GPLAQSVDSN KEEL*
mutated AA sequence MGLSAAAPLW GPPGLLLAIA LHPALSVPPR RDYCVLGAGP AGLQMAYFLQ RAGRDYAVFE
RAPRPGSFFT RYPRHRKLIS INKRYTGKAN AEFNLRHDWN SLLSHDPRLL FRHYSRAYFP
DARDMVRYLG DFADTLGLRV QYNTTIAHVT LDKDRQAWNG HYFILTDQKG QVHQCSVLLV
ATGLSVPNQV DFPGSEYAEG YESVSVDPED FVGQNVLILG RGNSAFETAE NILGVTNFIH
MLSRSRVRLS WATHYVGDLR AINNGLLDTY QLKSLDGLLE SDLTDLAILK DSKGKFHVTP
KFFLEEANTN QSADSITLPQ DDNDNFAMRV PYDRVIRCLG WNFDFSIFNK SLRLNSGNAF
GKKYPLIRAS YESKGSRGLF ILGTASHSVD YRKSAGGFIH GFRYTVRAVH RLLEHRHHSV
TWPATELPIT QLTSSIVRRV NEASGLYQMF GVLADVILLK ENSTAFEYLE EFPIQMLAQL
ETLTGRKAKH GLFVINMEYG RNFSGPDKDV FFDDRSVGHT EDAWQSNFLH PVIYYYRYLP
TEQEVRFRPA HWPLPRPTAI HHIVEDFLTD WTAPIGHILP LRRFLENCLD TDLRSFYAES
CFLFALTRQK LPPFCQQGYL RMQGLVSTES LWQHRVESRL LRDYAPTGRR LEDSSQQLGD
QEPLGSPLAP GPLAQSVDSN KEEL*
speed 1.29 s
All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table

Problems