MutationTaster - study a chromosomal position

NEVER press reload or F5 - unless you want to start from the very beginning.
input seems to be ok - now mapping the variant to the different transcripts...
found 3 transcript(s)...
Querying Taster for transcript #1: ENST00000264229
Querying Taster for transcript #2: ENST00000504228
Querying Taster for transcript #3: ENST00000541073
MT speed 0 s - this script 4.583944 s

Results

genesymbol	prediction	probability	model	prediction problem	splicing	ClinVar	amino acid changes	variant type	dbSNP ID	protein length	file
CRACD	polymorphism_automatic	1.86809456792503e-11	simple_aae				L269I	single base exchange	rs6823339		show file
CRACD	polymorphism_automatic	1.86809456792503e-11	simple_aae				L269I	single base exchange	rs6823339		show file
CRACD	polymorphism_automatic	1.86809456792503e-11	simple_aae				L262I	single base exchange	rs6823339		show file

Taster files

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999981319 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr4:57180473C>AN/A show variant in all transcripts IGV

HGNC symbol

CRACD

Ensembl transcript ID

ENST00000264229

Genbank transcript ID

N/A

UniProt peptide

Q6ZU35

alteration type

single base exchange

alteration region

CDS

DNA changes

c.805C>A
cDNA.1196C>A
g.144113C>A

AA changes

L269I Score: 5 explain score(s)

position(s) of altered AA
if AA alteration in CDS

269

frameshift

known variant

Reference ID: rs6823339

database	homozygous (A/A)	heterozygous	allele carriers
1000G	258	956	1214
ExAC	1647	5157	6804

regulatory features

Gene Associated, Regulatory Feature, Gene associated regulatory feature
H3K27me3, Histone, Histone 3 Lysine 27 Tri-Methylation
H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation
Znf263, Transcription Factor, Znf263 TF binding

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.482	0.054
	0.196	0.042
(flanking)	1.23	0.044

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

268

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

269

mutated

all conserved

269

Ptroglodytes

all identical

ENSPTRG00000016078

269

Mmulatta

all identical

ENSMMUG00000016358

269

Fcatus

no homologue

Mmusculus

all identical

ENSMUSG00000036377

269

EEEEVKEEGEEGEEVGLQPRAGK

Ggallus

not conserved

ENSGALG00000013771

268

Trubripes

not conserved

ENSTRUG00000015704

237

Drerio

not conserved

ENSDARG00000011602

230

FSE

Dmelanogaster

no homologue

Celegans

no homologue

Xtropicalis

no homologue

protein features

start (aa)	end (aa)	feature	details
209	529	COMPBIAS	Glu-rich.	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

3702 / 3702

position (AA) of stopcodon in wt / mu AA sequence

1234 / 1234

position of stopcodon in wt / mu cDNA

4093 / 4093

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

392 / 392

chromosome

strand

last intron/exon boundary

3933

theoretical NMD boundary in CDS

3491

length of CDS

3702

coding sequence (CDS) position

805

cDNA position
(for ins/del: last normal base / first normal base)

1196

gDNA position
(for ins/del: last normal base / first normal base)

144113

chromosomal position
(for ins/del: last normal base / first normal base)

57180473

original gDNA sequence snippet

AAGAGAACAGAAGGCAGGAGCTCTTGGAGGAGGAGGGCGAG

altered gDNA sequence snippet

AAGAGAACAGAAGGCAGGAGATCTTGGAGGAGGAGGGCGAG

original cDNA sequence snippet

AAGAGAACAGAAGGCAGGAGCTCTTGGAGGAGGAGGGCGAG

altered cDNA sequence snippet

AAGAGAACAGAAGGCAGGAGATCTTGGAGGAGGAGGGCGAG

wildtype AA sequence

MGTRAFSHDS IFIPDGGAES EQTVQAMSQD NILGKVKTLQ QQLGKNIKFG QRSPNAIPMN
KANSGEASLE EDLFLTSPME IVTQQDIVLS DAENKSSDTP SSLSPLNLPG AGSEMEEKVA
PVKPSRPKRH FSSAGTIESV NLDAIPLAIA RLDNSAAKHK LAVKPKKQRV SKKHRRLAQD
PQHEQGGLES RPCLDQNGHP GEDKPTWHEE EPNPLDSEEE RRRQEDYWRE LEAKCKRQKA
EAAEKRRLEE QRLQALERRL WEENRRQELL EEEGEGQEPP LEAERAPREE QQRSLEAPGW
EDAERREREE RERLEAEEER RRLQAQAQAE ERRRLEEDAR LEERRRQEEE EGRCAEELKR
QEEEEAEGWE ELEQQEAEVQ GPPEALEETG EGRRGAEEED LGEEEEEGQA HLEDWRGQLS
ELLNDFEERL EDQERLKPEG QREHSEEPGI CEEQNPEAER RREQQGRSGD FQGADRPGPE
EKREEGDTEP LLKQEGPVEA AQPPVERKEA AALEQGRKVE ELRWQEVDER QTMPRPYTFQ
VSSGGKQILF PKVNLSPVTP AKDTGLTAAP QEPKAPKASP VQHALPSSLS VPHTAILVTG
AQLCGPAVNL SQIKDTACKS LLGLEEKKHA EAPAGENPPR GPGDARAGSG KAKPRQESPS
SASALAEWAS IRSRILKNAE SDPRSSERDQ LRPGDESTPR GRCDSRGNQR KTPPVNAKFS
IMPAWQKFSD GGTETSKQST EAESIRKRPM LGPSEETAPQ PPPAGVRELG KGPEKSEMHR
EPADTTEGCK FAKDLPSFLV PSLPYPPQKV VAHTEFTTSS DSETANGIAK PDPVMPGGEE
KASPFGIKLR RTNYSLRFNC DQQAEQKKKK RHSSTGDSAD AGPPAAGSAR GEKEMEGVAL
KHGPSLPQER KQAPSTRRDS AEPSSSRSVP VAHPGPPPAS SQTPAPEHDK AANKMPLAQK
PALAPKPTSQ TPPASPLSKL SRPYLVELLS RRAGRPDPEP SEPSKEDQES SDRRPPSPPG
PEERKGQKRD EEEEATERKP ASPPLPATQQ EKPSQTPEAG RKEKPMLQSR HSLDGSKLTE
KVETAQPLWI TLALQKQKGF REQQATREER KQAREAKQAE KLSKENVSVS VQPGSSSVSR
AGSLHKSTAL PEEKRPETAV SRLERREQLK KANTLPTSVT VEISDSAPPA PLVKEVTKRF
STPDAAPVST EPAWLALAKR KAKAWSDCPQ IIK*

mutated AA sequence

MGTRAFSHDS IFIPDGGAES EQTVQAMSQD NILGKVKTLQ QQLGKNIKFG QRSPNAIPMN
KANSGEASLE EDLFLTSPME IVTQQDIVLS DAENKSSDTP SSLSPLNLPG AGSEMEEKVA
PVKPSRPKRH FSSAGTIESV NLDAIPLAIA RLDNSAAKHK LAVKPKKQRV SKKHRRLAQD
PQHEQGGLES RPCLDQNGHP GEDKPTWHEE EPNPLDSEEE RRRQEDYWRE LEAKCKRQKA
EAAEKRRLEE QRLQALERRL WEENRRQEIL EEEGEGQEPP LEAERAPREE QQRSLEAPGW
EDAERREREE RERLEAEEER RRLQAQAQAE ERRRLEEDAR LEERRRQEEE EGRCAEELKR
QEEEEAEGWE ELEQQEAEVQ GPPEALEETG EGRRGAEEED LGEEEEEGQA HLEDWRGQLS
ELLNDFEERL EDQERLKPEG QREHSEEPGI CEEQNPEAER RREQQGRSGD FQGADRPGPE
EKREEGDTEP LLKQEGPVEA AQPPVERKEA AALEQGRKVE ELRWQEVDER QTMPRPYTFQ
VSSGGKQILF PKVNLSPVTP AKDTGLTAAP QEPKAPKASP VQHALPSSLS VPHTAILVTG
AQLCGPAVNL SQIKDTACKS LLGLEEKKHA EAPAGENPPR GPGDARAGSG KAKPRQESPS
SASALAEWAS IRSRILKNAE SDPRSSERDQ LRPGDESTPR GRCDSRGNQR KTPPVNAKFS
IMPAWQKFSD GGTETSKQST EAESIRKRPM LGPSEETAPQ PPPAGVRELG KGPEKSEMHR
EPADTTEGCK FAKDLPSFLV PSLPYPPQKV VAHTEFTTSS DSETANGIAK PDPVMPGGEE
KASPFGIKLR RTNYSLRFNC DQQAEQKKKK RHSSTGDSAD AGPPAAGSAR GEKEMEGVAL
KHGPSLPQER KQAPSTRRDS AEPSSSRSVP VAHPGPPPAS SQTPAPEHDK AANKMPLAQK
PALAPKPTSQ TPPASPLSKL SRPYLVELLS RRAGRPDPEP SEPSKEDQES SDRRPPSPPG
PEERKGQKRD EEEEATERKP ASPPLPATQQ EKPSQTPEAG RKEKPMLQSR HSLDGSKLTE
KVETAQPLWI TLALQKQKGF REQQATREER KQAREAKQAE KLSKENVSVS VQPGSSSVSR
AGSLHKSTAL PEEKRPETAV SRLERREQLK KANTLPTSVT VEISDSAPPA PLVKEVTKRF
STPDAAPVST EPAWLALAKR KAKAWSDCPQ IIK*

speed

1.02 s

All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999981319 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr4:57180473C>AN/A show variant in all transcripts IGV

HGNC symbol

CRACD

Ensembl transcript ID

ENST00000504228

Genbank transcript ID

NM_020722

UniProt peptide

Q6ZU35

alteration type

single base exchange

alteration region

CDS

DNA changes

c.805C>A
cDNA.910C>A
g.144113C>A

AA changes

L269I Score: 5 explain score(s)

position(s) of altered AA
if AA alteration in CDS

269

frameshift

known variant

Reference ID: rs6823339

database	homozygous (A/A)	heterozygous	allele carriers
1000G	258	956	1214
ExAC	1647	5157	6804

regulatory features

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.482	0.054
	0.196	0.042
(flanking)	1.23	0.044

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

268

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

269

mutated

all conserved

269

Ptroglodytes

all identical

ENSPTRG00000016078

269

Mmulatta

all identical

ENSMMUG00000016358

269

Fcatus

no homologue

Mmusculus

all identical

ENSMUSG00000036377

269

EEEEVKEEGEEGEEVGLQPRAGK

Ggallus

not conserved

ENSGALG00000013771

268

Trubripes

not conserved

ENSTRUG00000015704

237

Drerio

not conserved

ENSDARG00000011602

230

FSE

Dmelanogaster

no homologue

Celegans

no homologue

Xtropicalis

no homologue

protein features

start (aa)	end (aa)	feature	details
209	529	COMPBIAS	Glu-rich.	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

3702 / 3702

position (AA) of stopcodon in wt / mu AA sequence

1234 / 1234

position of stopcodon in wt / mu cDNA

3807 / 3807

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

106 / 106

chromosome

strand

last intron/exon boundary

3647

theoretical NMD boundary in CDS

3491

length of CDS

3702

coding sequence (CDS) position

805

cDNA position
(for ins/del: last normal base / first normal base)

910

gDNA position
(for ins/del: last normal base / first normal base)

144113

chromosomal position
(for ins/del: last normal base / first normal base)

57180473

original gDNA sequence snippet

AAGAGAACAGAAGGCAGGAGCTCTTGGAGGAGGAGGGCGAG

altered gDNA sequence snippet

AAGAGAACAGAAGGCAGGAGATCTTGGAGGAGGAGGGCGAG

original cDNA sequence snippet

AAGAGAACAGAAGGCAGGAGCTCTTGGAGGAGGAGGGCGAG

altered cDNA sequence snippet

AAGAGAACAGAAGGCAGGAGATCTTGGAGGAGGAGGGCGAG

wildtype AA sequence

mutated AA sequence

MGTRAFSHDS IFIPDGGAES EQTVQAMSQD NILGKVKTLQ QQLGKNIKFG QRSPNAIPMN
KANSGEASLE EDLFLTSPME IVTQQDIVLS DAENKSSDTP SSLSPLNLPG AGSEMEEKVA
PVKPSRPKRH FSSAGTIESV NLDAIPLAIA RLDNSAAKHK LAVKPKKQRV SKKHRRLAQD
PQHEQGGLES RPCLDQNGHP GEDKPTWHEE EPNPLDSEEE RRRQEDYWRE LEAKCKRQKA
EAAEKRRLEE QRLQALERRL WEENRRQEIL EEEGEGQEPP LEAERAPREE QQRSLEAPGW
EDAERREREE RERLEAEEER RRLQAQAQAE ERRRLEEDAR LEERRRQEEE EGRCAEELKR
QEEEEAEGWE ELEQQEAEVQ GPPEALEETG EGRRGAEEED LGEEEEEGQA HLEDWRGQLS
ELLNDFEERL EDQERLKPEG QREHSEEPGI CEEQNPEAER RREQQGRSGD FQGADRPGPE
EKREEGDTEP LLKQEGPVEA AQPPVERKEA AALEQGRKVE ELRWQEVDER QTMPRPYTFQ
VSSGGKQILF PKVNLSPVTP AKDTGLTAAP QEPKAPKASP VQHALPSSLS VPHTAILVTG
AQLCGPAVNL SQIKDTACKS LLGLEEKKHA EAPAGENPPR GPGDARAGSG KAKPRQESPS
SASALAEWAS IRSRILKNAE SDPRSSERDQ LRPGDESTPR GRCDSRGNQR KTPPVNAKFS
IMPAWQKFSD GGTETSKQST EAESIRKRPM LGPSEETAPQ PPPAGVRELG KGPEKSEMHR
EPADTTEGCK FAKDLPSFLV PSLPYPPQKV VAHTEFTTSS DSETANGIAK PDPVMPGGEE
KASPFGIKLR RTNYSLRFNC DQQAEQKKKK RHSSTGDSAD AGPPAAGSAR GEKEMEGVAL
KHGPSLPQER KQAPSTRRDS AEPSSSRSVP VAHPGPPPAS SQTPAPEHDK AANKMPLAQK
PALAPKPTSQ TPPASPLSKL SRPYLVELLS RRAGRPDPEP SEPSKEDQES SDRRPPSPPG
PEERKGQKRD EEEEATERKP ASPPLPATQQ EKPSQTPEAG RKEKPMLQSR HSLDGSKLTE
KVETAQPLWI TLALQKQKGF REQQATREER KQAREAKQAE KLSKENVSVS VQPGSSSVSR
AGSLHKSTAL PEEKRPETAV SRLERREQLK KANTLPTSVT VEISDSAPPA PLVKEVTKRF
STPDAAPVST EPAWLALAKR KAKAWSDCPQ IIK*

speed

0.35 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999981319 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr4:57180473C>AN/A show variant in all transcripts IGV

HGNC symbol

CRACD

Ensembl transcript ID

ENST00000541073

Genbank transcript ID

N/A

UniProt peptide

Q6ZU35

alteration type

single base exchange

alteration region

CDS

DNA changes

c.784C>A
cDNA.932C>A
g.144113C>A

AA changes

L262I Score: 5 explain score(s)

position(s) of altered AA
if AA alteration in CDS

262

frameshift

known variant

Reference ID: rs6823339

database	homozygous (A/A)	heterozygous	allele carriers
1000G	258	956	1214
ExAC	1647	5157	6804

regulatory features

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.482	0.054
	0.196	0.042
(flanking)	1.23	0.044

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

no abrogation of potential splice sites

distance from splice site

268

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

262

mutated

all conserved

262

Ptroglodytes

all identical

ENSPTRG00000016078

269

Mmulatta

all identical

ENSMMUG00000016358

269

Fcatus

no homologue

Mmusculus

all identical

ENSMUSG00000036377

269

EEE

Ggallus

not conserved

ENSGALG00000013771

269

Trubripes

not conserved

ENSTRUG00000015704

234

Drerio

not conserved

ENSDARG00000011602

230

FSE

Dmelanogaster

no homologue

Celegans

no homologue

Xtropicalis

no homologue

protein features

start (aa)	end (aa)	feature	details
209	529	COMPBIAS	Glu-rich.	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

3681 / 3681

position (AA) of stopcodon in wt / mu AA sequence

1227 / 1227

position of stopcodon in wt / mu cDNA

3829 / 3829

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

149 / 149

chromosome

strand

last intron/exon boundary

3669

theoretical NMD boundary in CDS

3470

length of CDS

3681

coding sequence (CDS) position

784

cDNA position
(for ins/del: last normal base / first normal base)

932

gDNA position
(for ins/del: last normal base / first normal base)

144113

chromosomal position
(for ins/del: last normal base / first normal base)

57180473

original gDNA sequence snippet

AAGAGAACAGAAGGCAGGAGCTCTTGGAGGAGGAGGGCGAG

altered gDNA sequence snippet

AAGAGAACAGAAGGCAGGAGATCTTGGAGGAGGAGGGCGAG

original cDNA sequence snippet

AAGAGAACAGAAGGCAGGAGCTCTTGGAGGAGGAGGGCGAG

altered cDNA sequence snippet

AAGAGAACAGAAGGCAGGAGATCTTGGAGGAGGAGGGCGAG

wildtype AA sequence

MGEQKVSRQF KQCHRTTSWA KSKLFSRLSS MFLQQLGKNI KFGQRSPNAI PMNKANSGEA
SLEEDLFLTS PMEIVTQQDI VLSDAENKSS DTPSSLSPLN LPGAGSEMEE KVAPVKPSRP
KRHFSSAGTI ESVNLDAIPL AIARLDNSAA KHKLAVKPKK QRVSKKHRRL AQDPQHEQGG
LESRPCLDQN GHPGEDKPTW HEEEPNPLDS EEERRRQEDY WRELEAKCKR QKAEAAEKRR
LEEQRLQALE RRLWEENRRQ ELLEEEGEGQ EPPLEAERAP REEQQRSLEA PGWEDAERRE
REERERLEAE EERRRLQAQA QAEERRRLEE DARLEERRRQ EEEEGRCAEE LKRQEEEEAE
GWEELEQQEA EVQGPPEALE ETGEGRRGAE EEDLGEEEEE GQAHLEDWRG QLSELLNDFE
ERLEDQERLK PEGQREHSEE PGICEEQNPE AERRREQQGR SGDFQGADRP GPEEKREEGD
TEPLLKQEGP VEAAQPPVER KEAAALEQGR KVEELRWQEV DERQTMPRPY TFQVSSGGKQ
ILFPKVNLSP VTPAKDTGLT AAPQEPKAPK ASPVQHALPS SLSVPHTAIL VTGAQLCGPA
VNLSQIKDTA CKSLLGLEEK KHAEAPAGEN PPRGPGDARA GSGKAKPRQE SPSSASALAE
WASIRSRILK NAESDPRSSE RDQLRPGDES TPRGRCDSRG NQRKTPPVNA KFSIMPAWQK
FSDGGTETSK QSTEAESIRK RPMLGPSEET APQPPPAGVR ELGKGPEKSE MHREPADTTE
GCKFAKDLPS FLVPSLPYPP QKVVAHTEFT TSSDSETANG IAKPDPVMPG GEEKASPFGI
KLRRTNYSLR FNCDQQAEQK KKKRHSSTGD SADAGPPAAG SARGEKEMEG VALKHGPSLP
QERKQAPSTR RDSAEPSSSR SVPVAHPGPP PASSQTPAPE HDKAANKMPL AQKPALAPKP
TSQTPPASPL SKLSRPYLVE LLSRRAGRPD PEPSEPSKED QESSDRRPPS PPGPEERKGQ
KRDEEEEATE RKPASPPLPA TQQEKPSQTP EAGRKEKPML QSRHSLDGSK LTEKVETAQP
LWITLALQKQ KGFREQQATR EERKQAREAK QAEKLSKENV SVSVQPGSSS VSRAGSLHKS
TALPEEKRPE TAVSRLERRE QLKKANTLPT SVTVEISDSA PPAPLVKEVT KRFSTPDAAP
VSTEPAWLAL AKRKAKAWSD CPQIIK*

mutated AA sequence

MGEQKVSRQF KQCHRTTSWA KSKLFSRLSS MFLQQLGKNI KFGQRSPNAI PMNKANSGEA
SLEEDLFLTS PMEIVTQQDI VLSDAENKSS DTPSSLSPLN LPGAGSEMEE KVAPVKPSRP
KRHFSSAGTI ESVNLDAIPL AIARLDNSAA KHKLAVKPKK QRVSKKHRRL AQDPQHEQGG
LESRPCLDQN GHPGEDKPTW HEEEPNPLDS EEERRRQEDY WRELEAKCKR QKAEAAEKRR
LEEQRLQALE RRLWEENRRQ EILEEEGEGQ EPPLEAERAP REEQQRSLEA PGWEDAERRE
REERERLEAE EERRRLQAQA QAEERRRLEE DARLEERRRQ EEEEGRCAEE LKRQEEEEAE
GWEELEQQEA EVQGPPEALE ETGEGRRGAE EEDLGEEEEE GQAHLEDWRG QLSELLNDFE
ERLEDQERLK PEGQREHSEE PGICEEQNPE AERRREQQGR SGDFQGADRP GPEEKREEGD
TEPLLKQEGP VEAAQPPVER KEAAALEQGR KVEELRWQEV DERQTMPRPY TFQVSSGGKQ
ILFPKVNLSP VTPAKDTGLT AAPQEPKAPK ASPVQHALPS SLSVPHTAIL VTGAQLCGPA
VNLSQIKDTA CKSLLGLEEK KHAEAPAGEN PPRGPGDARA GSGKAKPRQE SPSSASALAE
WASIRSRILK NAESDPRSSE RDQLRPGDES TPRGRCDSRG NQRKTPPVNA KFSIMPAWQK
FSDGGTETSK QSTEAESIRK RPMLGPSEET APQPPPAGVR ELGKGPEKSE MHREPADTTE
GCKFAKDLPS FLVPSLPYPP QKVVAHTEFT TSSDSETANG IAKPDPVMPG GEEKASPFGI
KLRRTNYSLR FNCDQQAEQK KKKRHSSTGD SADAGPPAAG SARGEKEMEG VALKHGPSLP
QERKQAPSTR RDSAEPSSSR SVPVAHPGPP PASSQTPAPE HDKAANKMPL AQKPALAPKP
TSQTPPASPL SKLSRPYLVE LLSRRAGRPD PEPSEPSKED QESSDRRPPS PPGPEERKGQ
KRDEEEEATE RKPASPPLPA TQQEKPSQTP EAGRKEKPML QSRHSLDGSK LTEKVETAQP
LWITLALQKQ KGFREQQATR EERKQAREAK QAEKLSKENV SVSVQPGSSS VSRAGSLHKS
TALPEEKRPE TAVSRLERRE QLKKANTLPT SVTVEISDSA PPAPLVKEVT KRFSTPDAAP
VSTEPAWLAL AKRKAKAWSD CPQIIK*

speed

1.22 s

MutationTaster - study a chromosomal position

Results

Taster files

mutation t@sting

Prediction

polymorphism

mutation t@sting

Prediction

polymorphism

mutation t@sting

Prediction

polymorphism

Problems