Yum, tasty mutations...

MutationTaster - study a chromosomal position

 MTQE documentation
NEVER press reload or F5 - unless you want to start from the very beginning.
input seems to be ok - now mapping the variant to the different transcripts...
found 2 transcript(s)...
Querying Taster for transcript #1: ENST00000511368
Querying Taster for transcript #2: ENST00000274181
MT speed 0.35 s - this script 2.368224 s

Results

genesymbolpredictionprobabilitymodelprediction
problem		splicingClinVaramino acid changesvariant typedbSNP IDprotein lengthfile
ADAMTS16polymorphism_automatic1.60982338570648e-13simple_aaeaffectedP90Asingle base exchangers2086310show file
ADAMTS16polymorphism_automatic1.60982338570648e-13simple_aaeaffectedP90Asingle base exchangers2086310show file

Taster files

Yum, tasty mutations...

mutation t@sting

 documentation

Prediction

polymorphism

 Model: simple_aae, prob: 0.999999999999839 (classification due to TGP/ExAC, real probability is shown anyway)      (explain)
Summary
  • amino acid sequence changed
  • homozygous in TGP or ExAC
  • known disease mutation at this position (HGMD CM094240)
  • protein features (might be) affected
  • splice site changes
 hyperlink
analysed issue analysis result
name of alteration no title
alteration (phys. location) chr5:5146335C>GN/A show variant in all transcripts   IGV
HGNC symbol ADAMTS16
Ensembl transcript ID ENST00000511368
Genbank transcript ID N/A
UniProt peptide Q8TE57
alteration type single base exchange
alteration region CDS
DNA changes c.268C>G
cDNA.406C>G
g.5893C>G
AA changes P90A Score: 27 explain score(s)
position(s) of altered AA
if AA alteration in CDS		 90
frameshift no
known variant Reference ID: rs2086310
databasehomozygous (G/G)heterozygousallele carriers
1000G12529792231
ExAC---

known disease mutation at this position, please check HGMD for details (HGMD ID CM094240)
regulatory features H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation
Gene Associated, Regulatory Feature, Gene associated regulatory feature
H3K27ac, Histone, Histone 3 Lysine 27 Acetylation
DNase1, Open Chromatin, DNase1 Hypersensitive Site
phyloP / phastCons
PhyloPPhastCons
(flanking)0.4980
-0.7590
(flanking)3.3330.144
explain score(s) and/or inspect your position(s) in in UCSC Genome Browser
splice sites
effectgDNA positionscorewt detection sequence exon-intron border
Donor gained58890.33mu: AGAGCAGTGGCCGTG AGCA|gtgg
Donor gained58920.68mu: GCAGTGGCCGTGTCC AGTG|gccg
distance from splice site 93
Kozak consensus sequence altered? N/A
conservation
protein level for non-synonymous changes
speciesmatchgeneaaalignment
Human      90IMHHQRRRRAVPVSEVESLHLRLK
mutated  not conserved    90IMHHQRRRRAVAVSEVESLHLRL
Ptroglodytes  not conserved  ENSPTRG00000016710  90IMHHQRRRRAVAVSEVESLHLRL
Mmulatta  not conserved  ENSMMUG00000019205  90IMHHQRRRRAVTMSGVESLHLRL
Fcatus  not conserved  ENSFCAG00000003777  31ITHPQRRKRALAQLGVESLHLRL
Mmusculus  not conserved  ENSMUSG00000049538  86IMHYQRRRRRRAVTQPGGDALHLRL
Ggallus  no homologue    
Trubripes  not conserved  ENSTRUG00000006843  32VGHHHRRRRRSVTPGASSTINGGGETVHFRL
Drerio  not conserved  ENSDARG00000074646  91VSHQHRSKRSTDASTV---HFRL
Dmelanogaster  not conserved  FBgn0029791  83LDHRRHRQRRSLNSEHDTQAADLHLLL
Celegans  no homologue    
Xtropicalis  not conserved  ENSXETG00000019022  32ISHKHRKKRSAANIDNDAVHLKL
protein features
start (aa)end (aa)featuredetails 
25279PROPEPBy similarity. /FTId=PRO_0000029194.lost
9090CONFLICTP -> A (in Ref. 1; CAC86015).lost
104104CONFLICTS -> P (in Ref. 1; CAC86015).might get lost (downstream of altered splice site)
156156CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
247254MOTIFCysteine switch (By similarity).might get lost (downstream of altered splice site)
249249METALZinc; in inhibited form (By similarity).might get lost (downstream of altered splice site)
284284CONFLICTS -> Y (in Ref. 4; BAC23125).might get lost (downstream of altered splice site)
290495DOMAINPeptidase M12B.might get lost (downstream of altered splice site)
310310CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
411411DISULFIDBy similarity.might get lost (downstream of altered splice site)
433433METALZinc; catalytic (By similarity).might get lost (downstream of altered splice site)
434434ACT_SITEBy similarity.might get lost (downstream of altered splice site)
437437METALZinc; catalytic (By similarity).might get lost (downstream of altered splice site)
443443METALZinc; catalytic (By similarity).might get lost (downstream of altered splice site)
450450DISULFIDBy similarity.might get lost (downstream of altered splice site)
474474DISULFIDBy similarity.might get lost (downstream of altered splice site)
490490DISULFIDBy similarity.might get lost (downstream of altered splice site)
496585DOMAINDisintegrin.might get lost (downstream of altered splice site)
586641DOMAINTSP type-1 1.might get lost (downstream of altered splice site)
598598DISULFIDBy similarity.might get lost (downstream of altered splice site)
602602DISULFIDBy similarity.might get lost (downstream of altered splice site)
613613DISULFIDBy similarity.might get lost (downstream of altered splice site)
625625DISULFIDBy similarity.might get lost (downstream of altered splice site)
635635DISULFIDBy similarity.might get lost (downstream of altered splice site)
640640DISULFIDBy similarity.might get lost (downstream of altered splice site)
642746COMPBIASCys-rich.might get lost (downstream of altered splice site)
741741CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
747873REGIONSpacer.might get lost (downstream of altered splice site)
780780CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
835835CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
874922DOMAINTSP type-1 2.might get lost (downstream of altered splice site)
905905CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
927987DOMAINTSP type-1 3.might get lost (downstream of altered splice site)
935935CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
939939DISULFIDBy similarity.might get lost (downstream of altered splice site)
943943DISULFIDBy similarity.might get lost (downstream of altered splice site)
954954DISULFIDBy similarity.might get lost (downstream of altered splice site)
970970DISULFIDBy similarity.might get lost (downstream of altered splice site)
981981DISULFIDBy similarity.might get lost (downstream of altered splice site)
986986DISULFIDBy similarity.might get lost (downstream of altered splice site)
9881048DOMAINTSP type-1 4.might get lost (downstream of altered splice site)
10511115DOMAINTSP type-1 5.might get lost (downstream of altered splice site)
10961096MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
11271181DOMAINTSP type-1 6.might get lost (downstream of altered splice site)
11861223DOMAINPLAC.might get lost (downstream of altered splice site)
length of protein normal
AA sequence altered yes
position of stopcodon in wt / mu CDS 1713 / 1713
position (AA) of stopcodon in wt / mu AA sequence 571 / 571
position of stopcodon in wt / mu cDNA 1851 / 1851
poly(A) signal N/A
conservation
nucleotide level for all changes - no scoring up to now		 N/A
position of start ATG in wt / mu cDNA 139 / 139
chromosome 5
strand 1
last intron/exon boundary 1744
theoretical NMD boundary in CDS 1555
length of CDS 1713
coding sequence (CDS) position 268
cDNA position
(for ins/del: last normal base / first normal base)		 406
gDNA position
(for ins/del: last normal base / first normal base)		 5893
chromosomal position
(for ins/del: last normal base / first normal base)		 5146335
original gDNA sequence snippet AGCGGCGGAGAAGAGCAGTGCCCGTGTCCGAGGTTGAGTCT
altered gDNA sequence snippet AGCGGCGGAGAAGAGCAGTGGCCGTGTCCGAGGTTGAGTCT
original cDNA sequence snippet AGCGGCGGAGAAGAGCAGTGCCCGTGTCCGAGGTTGAGTCT
altered cDNA sequence snippet AGCGGCGGAGAAGAGCAGTGGCCGTGTCCGAGGTTGAGTCT
wildtype AA sequence MKPRARGWRG LAALWMLLAQ VAEQAPACAM GPAAAAPGSP SVPRPPPPAE RPGWMEKGEY
DLVSAYEVDH RGDYVSHEIM HHQRRRRAVP VSEVESLHLR LKGSRHDFHM DLRTSSSLVA
PGFIVQTLGK TGTKSVQTLP PEDFCFYQGS LRSHRNSSVA LSTCQGLSGM IRTEEADYFL
RPLPSHLSWK LGRAAQGSSP SHVLYKRSTE PHAPGASEVL VTSRTWELAH QPLHSSDLRL
GLPQKQHFCG RRKKYMPQPP KEDLFILPDE YKSCLRHKRS LLRSHRNEEL NVETLVVVDK
KMMQNHGHEN ITTYVLTILN MVSALFKDGT IGGNINIAIV GLILLEDEQP GLVISHHADH
TLSSFCQWQS GLMGKDGTRH DHAILLTGLD ICSWKNEPCD TLGFAPISGM CSKYRSCTIN
EDTGLGLAFT IAHESGHNFG MIHDGEGNMC KKSEGNIMSP TLAGRNGVFS WSPCSRQYLH
KFLSTAQAIC LADQPKPVKE YKYPEKLPGE LYDANTQCKW QFGEKAKLCM LDFKKDICKA
LWCHRIGRKC ETKFMPAAEG TICGHDMVRS *
mutated AA sequence MKPRARGWRG LAALWMLLAQ VAEQAPACAM GPAAAAPGSP SVPRPPPPAE RPGWMEKGEY
DLVSAYEVDH RGDYVSHEIM HHQRRRRAVA VSEVESLHLR LKGSRHDFHM DLRTSSSLVA
PGFIVQTLGK TGTKSVQTLP PEDFCFYQGS LRSHRNSSVA LSTCQGLSGM IRTEEADYFL
RPLPSHLSWK LGRAAQGSSP SHVLYKRSTE PHAPGASEVL VTSRTWELAH QPLHSSDLRL
GLPQKQHFCG RRKKYMPQPP KEDLFILPDE YKSCLRHKRS LLRSHRNEEL NVETLVVVDK
KMMQNHGHEN ITTYVLTILN MVSALFKDGT IGGNINIAIV GLILLEDEQP GLVISHHADH
TLSSFCQWQS GLMGKDGTRH DHAILLTGLD ICSWKNEPCD TLGFAPISGM CSKYRSCTIN
EDTGLGLAFT IAHESGHNFG MIHDGEGNMC KKSEGNIMSP TLAGRNGVFS WSPCSRQYLH
KFLSTAQAIC LADQPKPVKE YKYPEKLPGE LYDANTQCKW QFGEKAKLCM LDFKKDICKA
LWCHRIGRKC ETKFMPAAEG TICGHDMVRS *
speed 0.10 s
All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table
Yum, tasty mutations...

mutation t@sting

 documentation

Prediction

polymorphism

 Model: simple_aae, prob: 0.999999999999839 (classification due to TGP/ExAC, real probability is shown anyway)      (explain)
Summary
  • amino acid sequence changed
  • homozygous in TGP or ExAC
  • known disease mutation at this position (HGMD CM094240)
  • protein features (might be) affected
  • splice site changes
 hyperlink
analysed issue analysis result
name of alteration no title
alteration (phys. location) chr5:5146335C>GN/A show variant in all transcripts   IGV
HGNC symbol ADAMTS16
Ensembl transcript ID ENST00000274181
Genbank transcript ID NM_139056
UniProt peptide Q8TE57
alteration type single base exchange
alteration region CDS
DNA changes c.268C>G
cDNA.406C>G
g.5893C>G
AA changes P90A Score: 27 explain score(s)
position(s) of altered AA
if AA alteration in CDS		 90
frameshift no
known variant Reference ID: rs2086310
databasehomozygous (G/G)heterozygousallele carriers
1000G12529792231
ExAC---

known disease mutation at this position, please check HGMD for details (HGMD ID CM094240)
regulatory features H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation
Gene Associated, Regulatory Feature, Gene associated regulatory feature
H3K27ac, Histone, Histone 3 Lysine 27 Acetylation
DNase1, Open Chromatin, DNase1 Hypersensitive Site
phyloP / phastCons
PhyloPPhastCons
(flanking)0.4980
-0.7590
(flanking)3.3330.144
explain score(s) and/or inspect your position(s) in in UCSC Genome Browser
splice sites
effectgDNA positionscorewt detection sequence exon-intron border
Donor gained58890.33mu: AGAGCAGTGGCCGTG AGCA|gtgg
Donor gained58920.68mu: GCAGTGGCCGTGTCC AGTG|gccg
distance from splice site 93
Kozak consensus sequence altered? N/A
conservation
protein level for non-synonymous changes
speciesmatchgeneaaalignment
Human      90IMHHQRRRRAVPVSEVESLHLRLK
mutated  not conserved    90IMHHQRRRRAVAVSEVESLHLRL
Ptroglodytes  not conserved  ENSPTRG00000016710  90IMHHQRRRRAVAVSEVESLHLRL
Mmulatta  not conserved  ENSMMUG00000019205  90IMHHQRRRRAVTMSGVESLHLRL
Fcatus  not conserved  ENSFCAG00000003777  31ITHPQRRKRALAQLGVESLHLRL
Mmusculus  not conserved  ENSMUSG00000049538  86IMHYQRRRRRRAVTQPGGDALHLRL
Ggallus  no homologue    
Trubripes  not conserved  ENSTRUG00000006843  32VGHHHRRRRRSVTPGASSTINGGGETVHFRL
Drerio  not conserved  ENSDARG00000074646  91VSHQHRSKRSTDASTV---HFRL
Dmelanogaster  not conserved  FBgn0029791  83LDHRRHRQRRSLNSEHDTQAADLHLLL
Celegans  no homologue    
Xtropicalis  not conserved  ENSXETG00000019022  32ISHKHRKKRSAANIDNDAVHLKL
protein features
start (aa)end (aa)featuredetails 
25279PROPEPBy similarity. /FTId=PRO_0000029194.lost
9090CONFLICTP -> A (in Ref. 1; CAC86015).lost
104104CONFLICTS -> P (in Ref. 1; CAC86015).might get lost (downstream of altered splice site)
156156CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
247254MOTIFCysteine switch (By similarity).might get lost (downstream of altered splice site)
249249METALZinc; in inhibited form (By similarity).might get lost (downstream of altered splice site)
284284CONFLICTS -> Y (in Ref. 4; BAC23125).might get lost (downstream of altered splice site)
290495DOMAINPeptidase M12B.might get lost (downstream of altered splice site)
310310CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
411411DISULFIDBy similarity.might get lost (downstream of altered splice site)
433433METALZinc; catalytic (By similarity).might get lost (downstream of altered splice site)
434434ACT_SITEBy similarity.might get lost (downstream of altered splice site)
437437METALZinc; catalytic (By similarity).might get lost (downstream of altered splice site)
443443METALZinc; catalytic (By similarity).might get lost (downstream of altered splice site)
450450DISULFIDBy similarity.might get lost (downstream of altered splice site)
474474DISULFIDBy similarity.might get lost (downstream of altered splice site)
490490DISULFIDBy similarity.might get lost (downstream of altered splice site)
496585DOMAINDisintegrin.might get lost (downstream of altered splice site)
586641DOMAINTSP type-1 1.might get lost (downstream of altered splice site)
598598DISULFIDBy similarity.might get lost (downstream of altered splice site)
602602DISULFIDBy similarity.might get lost (downstream of altered splice site)
613613DISULFIDBy similarity.might get lost (downstream of altered splice site)
625625DISULFIDBy similarity.might get lost (downstream of altered splice site)
635635DISULFIDBy similarity.might get lost (downstream of altered splice site)
640640DISULFIDBy similarity.might get lost (downstream of altered splice site)
642746COMPBIASCys-rich.might get lost (downstream of altered splice site)
741741CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
747873REGIONSpacer.might get lost (downstream of altered splice site)
780780CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
835835CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
874922DOMAINTSP type-1 2.might get lost (downstream of altered splice site)
905905CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
927987DOMAINTSP type-1 3.might get lost (downstream of altered splice site)
935935CARBOHYDN-linked (GlcNAc...) (Potential).might get lost (downstream of altered splice site)
939939DISULFIDBy similarity.might get lost (downstream of altered splice site)
943943DISULFIDBy similarity.might get lost (downstream of altered splice site)
954954DISULFIDBy similarity.might get lost (downstream of altered splice site)
970970DISULFIDBy similarity.might get lost (downstream of altered splice site)
981981DISULFIDBy similarity.might get lost (downstream of altered splice site)
986986DISULFIDBy similarity.might get lost (downstream of altered splice site)
9881048DOMAINTSP type-1 4.might get lost (downstream of altered splice site)
10511115DOMAINTSP type-1 5.might get lost (downstream of altered splice site)
10961096MOD_RESPhosphoserine.might get lost (downstream of altered splice site)
11271181DOMAINTSP type-1 6.might get lost (downstream of altered splice site)
11861223DOMAINPLAC.might get lost (downstream of altered splice site)
length of protein normal
AA sequence altered yes
position of stopcodon in wt / mu CDS 3675 / 3675
position (AA) of stopcodon in wt / mu AA sequence 1225 / 1225
position of stopcodon in wt / mu cDNA 3813 / 3813
poly(A) signal N/A
conservation
nucleotide level for all changes - no scoring up to now		 N/A
position of start ATG in wt / mu cDNA 139 / 139
chromosome 5
strand 1
last intron/exon boundary 3698
theoretical NMD boundary in CDS 3509
length of CDS 3675
coding sequence (CDS) position 268
cDNA position
(for ins/del: last normal base / first normal base)		 406
gDNA position
(for ins/del: last normal base / first normal base)		 5893
chromosomal position
(for ins/del: last normal base / first normal base)		 5146335
original gDNA sequence snippet AGCGGCGGAGAAGAGCAGTGCCCGTGTCCGAGGTTGAGTCT
altered gDNA sequence snippet AGCGGCGGAGAAGAGCAGTGGCCGTGTCCGAGGTTGAGTCT
original cDNA sequence snippet AGCGGCGGAGAAGAGCAGTGCCCGTGTCCGAGGTTGAGTCT
altered cDNA sequence snippet AGCGGCGGAGAAGAGCAGTGGCCGTGTCCGAGGTTGAGTCT
wildtype AA sequence MKPRARGWRG LAALWMLLAQ VAEQAPACAM GPAAAAPGSP SVPRPPPPAE RPGWMEKGEY
DLVSAYEVDH RGDYVSHEIM HHQRRRRAVP VSEVESLHLR LKGSRHDFHM DLRTSSSLVA
PGFIVQTLGK TGTKSVQTLP PEDFCFYQGS LRSHRNSSVA LSTCQGLSGM IRTEEADYFL
RPLPSHLSWK LGRAAQGSSP SHVLYKRSTE PHAPGASEVL VTSRTWELAH QPLHSSDLRL
GLPQKQHFCG RRKKYMPQPP KEDLFILPDE YKSCLRHKRS LLRSHRNEEL NVETLVVVDK
KMMQNHGHEN ITTYVLTILN MVSALFKDGT IGGNINIAIV GLILLEDEQP GLVISHHADH
TLSSFCQWQS GLMGKDGTRH DHAILLTGLD ICSWKNEPCD TLGFAPISGM CSKYRSCTIN
EDTGLGLAFT IAHESGHNFG MIHDGEGNMC KKSEGNIMSP TLAGRNGVFS WSPCSRQYLH
KFLSTAQAIC LADQPKPVKE YKYPEKLPGE LYDANTQCKW QFGEKAKLCM LDFKKDICKA
LWCHRIGRKC ETKFMPAAEG TICGHDMWCR GGQCVKYGDE GPKPTHGHWS DWSSWSPCSR
TCGGGVSHRS RLCTNPKPSH GGKFCEGSTR TLKLCNSQKC PRDSVDFRAA QCAEHNSRRF
RGRHYKWKPY TQVEDQDLCK LYCIAEGFDF FFSLSNKVKD GTPCSEDSRN VCIDGICERV
GCDNVLGSDA VEDVCGVCNG NNSACTIHRG LYTKHHHTNQ YYHMVTIPSG ARSIRIYEMN
VSTSYISVRN ALRRYYLNGH WTVDWPGRYK FSGTTFDYRR SYNEPENLIA TGPTNETLIV
ELLFQGRNPG VAWEYSMPRL GTEKQPPAQP SYTWAIVRSE CSVSCGGGQM TVREGCYRDL
KFQVNMSFCN PKTRPVTGLV PCKVSACPPS WSVGNWSACS RTCGGGAQSR PVQCTRRVHY
DSEPVPASLC PQPAPSSRQA CNSQSCPPAW SAGPWAECSH TCGKGWRKRA VACKSTNPSA
RAQLLPDAVC TSEPKPRMHE ACLLQRCHKP KKLQWLVSAW SQCSVTCERG TQKRFLKCAE
KYVSGKYREL ASKKCSHLPK PSLELERACA PLPCPRHPPF AAAGPSRGSW FASPWSQCTA
SCGGGVQTRS VQCLAGGRPA SGCLLHQKPS ASLACNTHFC PIAEKKDAFC KDYFHWCYLV
PQHGMCSHKF YGKQCCKTCS KSNL*
mutated AA sequence MKPRARGWRG LAALWMLLAQ VAEQAPACAM GPAAAAPGSP SVPRPPPPAE RPGWMEKGEY
DLVSAYEVDH RGDYVSHEIM HHQRRRRAVA VSEVESLHLR LKGSRHDFHM DLRTSSSLVA
PGFIVQTLGK TGTKSVQTLP PEDFCFYQGS LRSHRNSSVA LSTCQGLSGM IRTEEADYFL
RPLPSHLSWK LGRAAQGSSP SHVLYKRSTE PHAPGASEVL VTSRTWELAH QPLHSSDLRL
GLPQKQHFCG RRKKYMPQPP KEDLFILPDE YKSCLRHKRS LLRSHRNEEL NVETLVVVDK
KMMQNHGHEN ITTYVLTILN MVSALFKDGT IGGNINIAIV GLILLEDEQP GLVISHHADH
TLSSFCQWQS GLMGKDGTRH DHAILLTGLD ICSWKNEPCD TLGFAPISGM CSKYRSCTIN
EDTGLGLAFT IAHESGHNFG MIHDGEGNMC KKSEGNIMSP TLAGRNGVFS WSPCSRQYLH
KFLSTAQAIC LADQPKPVKE YKYPEKLPGE LYDANTQCKW QFGEKAKLCM LDFKKDICKA
LWCHRIGRKC ETKFMPAAEG TICGHDMWCR GGQCVKYGDE GPKPTHGHWS DWSSWSPCSR
TCGGGVSHRS RLCTNPKPSH GGKFCEGSTR TLKLCNSQKC PRDSVDFRAA QCAEHNSRRF
RGRHYKWKPY TQVEDQDLCK LYCIAEGFDF FFSLSNKVKD GTPCSEDSRN VCIDGICERV
GCDNVLGSDA VEDVCGVCNG NNSACTIHRG LYTKHHHTNQ YYHMVTIPSG ARSIRIYEMN
VSTSYISVRN ALRRYYLNGH WTVDWPGRYK FSGTTFDYRR SYNEPENLIA TGPTNETLIV
ELLFQGRNPG VAWEYSMPRL GTEKQPPAQP SYTWAIVRSE CSVSCGGGQM TVREGCYRDL
KFQVNMSFCN PKTRPVTGLV PCKVSACPPS WSVGNWSACS RTCGGGAQSR PVQCTRRVHY
DSEPVPASLC PQPAPSSRQA CNSQSCPPAW SAGPWAECSH TCGKGWRKRA VACKSTNPSA
RAQLLPDAVC TSEPKPRMHE ACLLQRCHKP KKLQWLVSAW SQCSVTCERG TQKRFLKCAE
KYVSGKYREL ASKKCSHLPK PSLELERACA PLPCPRHPPF AAAGPSRGSW FASPWSQCTA
SCGGGVQTRS VQCLAGGRPA SGCLLHQKPS ASLACNTHFC PIAEKKDAFC KDYFHWCYLV
PQHGMCSHKF YGKQCCKTCS KSNL*
speed 0.25 s
All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table

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