MutationTaster - study a chromosomal position

NEVER press reload or F5 - unless you want to start from the very beginning.
input seems to be ok - now mapping the variant to the different transcripts...
found 3 transcript(s)...
Querying Taster for transcript #1: ENST00000389536
Querying Taster for transcript #2: ENST00000311202
Querying Taster for transcript #3: ENST00000351747
MT speed 0 s - this script 3.848064 s

Results

genesymbol	prediction	probability	model	prediction problem	splicing	ClinVar	amino acid changes	variant type	dbSNP ID	protein length	file
DNAH12	polymorphism_automatic	1.6530110613644e-12	simple_aae				V32A	single base exchange	rs9311651		show file
DNAH12	polymorphism_automatic	1.6530110613644e-12	simple_aae				V32A	single base exchange	rs9311651		show file
DNAH12	polymorphism_automatic	1.6530110613644e-12	simple_aae				V32A	single base exchange	rs9311651		show file

Taster files

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999998347 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr3:57528503A>GN/A show variant in all transcripts IGV

HGNC symbol

DNAH12

Ensembl transcript ID

ENST00000311202

Genbank transcript ID

NM_198564

UniProt peptide

Q6ZR08

alteration type

single base exchange

alteration region

CDS

DNA changes

c.95T>C
cDNA.273T>C
g.1569T>C

AA changes

V32A Score: 64 explain score(s)

position(s) of altered AA
if AA alteration in CDS

frameshift

known variant

Reference ID: rs9311651

database	homozygous (G/G)	heterozygous	allele carriers
1000G	227	630	857
ExAC	2489	14720	17209

regulatory features

N/A

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.15	0
	-0.396	0
(flanking)	1.289	0.006

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor marginally increased	1560	wt: 0.8132 / mu: 0.8665 (marginal change - not scored)	wt: AGAAAACATAGGCGT mu: AGAAAACATAGGCGC	AAAA\|cata

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

mutated

not conserved

Ptroglodytes

no homologue

Mmulatta

all identical

ENSMMUG00000004881

Fcatus

no homologue

Mmusculus

no homologue

Ggallus

no homologue

Trubripes

no homologue

Drerio

no homologue

Dmelanogaster

no homologue

Celegans

no homologue

Xtropicalis

no homologue

protein features

start (aa)	end (aa)	feature	details
1	1214	REGION	Stem (By similarity).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

1374 / 1374

position (AA) of stopcodon in wt / mu AA sequence

458 / 458

position of stopcodon in wt / mu cDNA

1552 / 1552

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

179 / 179

chromosome

strand

-1

last intron/exon boundary

1514

theoretical NMD boundary in CDS

1285

length of CDS

1374

coding sequence (CDS) position

cDNA position
(for ins/del: last normal base / first normal base)

273

gDNA position
(for ins/del: last normal base / first normal base)

1569

chromosomal position
(for ins/del: last normal base / first normal base)

57528503

original gDNA sequence snippet

TCTCCCAGAAAACATAGGCGTTGATACACCAACACAAAGTA

altered gDNA sequence snippet

TCTCCCAGAAAACATAGGCGCTGATACACCAACACAAAGTA

original cDNA sequence snippet

TCTCCCAGAAAACATAGGCGTTGATACACCAACACAAAGTA

altered cDNA sequence snippet

TCTCCCAGAAAACATAGGCGCTGATACACCAACACAAAGTA

wildtype AA sequence

mutated AA sequence

speed

0.66 s

All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999998347 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr3:57528503A>GN/A show variant in all transcripts IGV

HGNC symbol

DNAH12

Ensembl transcript ID

ENST00000389536

Genbank transcript ID

N/A

UniProt peptide

Q6ZR08

alteration type

single base exchange

alteration region

CDS

DNA changes

c.95T>C
cDNA.276T>C
g.1569T>C

AA changes

V32A Score: 64 explain score(s)

position(s) of altered AA
if AA alteration in CDS

frameshift

known variant

Reference ID: rs9311651

database	homozygous (G/G)	heterozygous	allele carriers
1000G	227	630	857
ExAC	2489	14720	17209

regulatory features

N/A

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.15	0
	-0.396	0
(flanking)	1.289	0.006

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor marginally increased	1560	wt: 0.8132 / mu: 0.8665 (marginal change - not scored)	wt: AGAAAACATAGGCGT mu: AGAAAACATAGGCGC	AAAA\|cata

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

mutated

not conserved

Ptroglodytes

no homologue

Mmulatta

all identical

ENSMMUG00000004881

Fcatus

no homologue

Mmusculus

no homologue

Ggallus

no homologue

Trubripes

no homologue

Drerio

no homologue

Dmelanogaster

no homologue

Celegans

no homologue

Xtropicalis

no homologue

protein features

start (aa)	end (aa)	feature	details
1	1214	REGION	Stem (By similarity).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2355 / 2355

position (AA) of stopcodon in wt / mu AA sequence

785 / 785

position of stopcodon in wt / mu cDNA

2536 / 2536

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

182 / 182

chromosome

strand

-1

last intron/exon boundary

2287

theoretical NMD boundary in CDS

2055

length of CDS

2355

coding sequence (CDS) position

cDNA position
(for ins/del: last normal base / first normal base)

276

gDNA position
(for ins/del: last normal base / first normal base)

1569

chromosomal position
(for ins/del: last normal base / first normal base)

57528503

original gDNA sequence snippet

TCTCCCAGAAAACATAGGCGTTGATACACCAACACAAAGTA

altered gDNA sequence snippet

TCTCCCAGAAAACATAGGCGCTGATACACCAACACAAAGTA

original cDNA sequence snippet

TCTCCCAGAAAACATAGGCGTTGATACACCAACACAAAGTA

altered cDNA sequence snippet

TCTCCCAGAAAACATAGGCGCTGATACACCAACACAAAGTA

wildtype AA sequence

mutated AA sequence

speed

1.12 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.999999999998347 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr3:57528503A>GN/A show variant in all transcripts IGV

HGNC symbol

DNAH12

Ensembl transcript ID

ENST00000351747

Genbank transcript ID

NM_178504

UniProt peptide

Q6ZR08

alteration type

single base exchange

alteration region

CDS

DNA changes

c.95T>C
cDNA.276T>C
g.1569T>C

AA changes

V32A Score: 64 explain score(s)

position(s) of altered AA
if AA alteration in CDS

frameshift

known variant

Reference ID: rs9311651

database	homozygous (G/G)	heterozygous	allele carriers
1000G	227	630	857
ExAC	2489	14720	17209

regulatory features

N/A

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.15	0
	-0.396	0
(flanking)	1.289	0.006

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor marginally increased	1560	wt: 0.8132 / mu: 0.8665 (marginal change - not scored)	wt: AGAAAACATAGGCGT mu: AGAAAACATAGGCGC	AAAA\|cata

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

mutated

not conserved

Ptroglodytes

no homologue

Mmulatta

all identical

ENSMMUG00000004881

Fcatus

no homologue

Mmusculus

no homologue

Ggallus

no homologue

Trubripes

no homologue

Drerio

no homologue

Dmelanogaster

no homologue

Celegans

no homologue

Xtropicalis

no homologue

protein features

start (aa)	end (aa)	feature	details
1	1214	REGION	Stem (By similarity).	lost

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

9279 / 9279

position (AA) of stopcodon in wt / mu AA sequence

3093 / 3093

position of stopcodon in wt / mu cDNA

9460 / 9460

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

182 / 182

chromosome

strand

-1

last intron/exon boundary

9270

theoretical NMD boundary in CDS

9038

length of CDS

9279

coding sequence (CDS) position

cDNA position
(for ins/del: last normal base / first normal base)

276

gDNA position
(for ins/del: last normal base / first normal base)

1569

chromosomal position
(for ins/del: last normal base / first normal base)

57528503

original gDNA sequence snippet

TCTCCCAGAAAACATAGGCGTTGATACACCAACACAAAGTA

altered gDNA sequence snippet

TCTCCCAGAAAACATAGGCGCTGATACACCAACACAAAGTA

original cDNA sequence snippet

TCTCCCAGAAAACATAGGCGTTGATACACCAACACAAAGTA

altered cDNA sequence snippet

TCTCCCAGAAAACATAGGCGCTGATACACCAACACAAAGTA

wildtype AA sequence

MSDANKAAIA AEKEALNLKL PPIVHLPENI GVDTPTQSKL LKYRRSKEQQ QKINQLVIDG
AKRNLDRTLG KRTPLLPPPD YPQTMTSEMK KKGFNYIYMK QCVESSPLVP IQQEWLDHML
RLIPESLKEG KEREELLESL INEVSSDFEN SMKRYLVQSV LVKPPVKSLE DEGGPLPESP
VGLDYSNPWH SSYVQARNQI FSNLHIIHPT MKMLLDLGYT TFADTVLLDF TGIRAKGPID
CESLKTDLSI QTRNAEEKIM NTWYPKVINL FTKKEALEGV KPEKLDAFYS CVSTLMSNQL
KDLLRRTVEG FVKLFDPKDQ QRLPIFKIEL TFDDDKMEFY PTFQDLEDNV LSLVERIAEA
LQNVQTIPSW LSGTSTPVNL DTELPEHVLH WAVDTLKAAV HRNLEGARKH YETYVEKYNW
LLDGTAVENI ETFQTEDHTF DEYTEFIEKF LSLASEIMLL PQWIHYTMVR LDCEDLKTGL
TNKAKAFANI LLNDIASKYR KENECICSEF EAIKEHALKV PETTEEMMDL ISYVEKARTV
GIEELILRIQ ESKRQMSYFL DVFLFPQEDL ALNATVLMWP RKINPIFDEN DELIENAKHK
KENELMAKRE KLILEIEKES RRMEEFTEFA ELERMQQYVT DVRQLQKRIQ ESEEAVQFIN
KEEELFKWEL TKYPELDKLK VNIEPYQKFF NFVLKWQRSE KRWMDGGFLD LNGESMEADV
EEFSREIFKT LKFFQTKLKK ELQEKRKAAR KRSLEEEKIE EEPKDNATIT MCRMRARHWK
QISEIVGYDL TPDSGTTLRK VLKLNLTPYL EQFEVISAGA SKEFSLEKAM NTMIGTWEDI
AFHISLYRDT GVCILSSVDE IQAILDDQII KTQTMRGSPF IKPFEHEIKA WEDRLIRIQE
TIDEWLKVQA QWLYLEPIFC SEDIMQQMPE EGRQFQTVDR HWRDIMKFCA KDPKVLAATS
LTGLLEKLQN CNELLEKIMK GLNAYLEKKR LFFPRFFFLS NDEMLEILSE TKDPLRVQPH
LKKCFEGIAK LEFLPNLDIK AMYSSEGERV ELIALISTSA ARGAVEKWLI QVEDLMLRSV
HDVIAAARLA YPESARRDWV REWPGQVVLC ISQMFWTSET QEVISGGTEG LKKYYKELQN
QLNEIVELVR GKLSKQTRTT LGALVTIDVH ARDVVMDMIK MGVSHDTDFL WLAQLRYYWE
NENARVRIIN CNVKYAYEYL GNSPRLVITP LTDRCYRTLI GAFYLNLGGA PEGPAGTGKT
ETTKDLAKAL AVQCVVFNCS DGLDYLAMGK FFKGLASSGA WACFDEFNRI ELEVLSVVAQ
QILCIQRAIQ QKLVVFVFEG TELKLNPNCF VAITMNPGYA GRSELPDNLK VLFRTVAMMV
PNYALIAEIS LYSYGFLNAR PLSVKIVMTY RLCSEQLSSQ FHYDYGMRAV KAVLVAAGNL
KLKYPNENED ILLLRSIKDV NEPKFLSHDI PLFNGITSDL FPGIKLPEAD YHEFLECAHE
ACNVHNLQPV KFFLEKIIQT YEMMIVRHGF MLVGEPFAAK TKVLHVLADT LTLMNEHGYG
EEEKVIYRTV NPKSITMGQL FGQFDPVSHE WTDGIVANTF REFALSETPD RKWVVFDGPI
DTLWIESMNT VLDDNKKLCL MSGEIIQMSP QMSLIFETMD LSQASPATVS RCGMIYLEPS
QLGWEPLVSS WLNSLKGPLC EPEYQALLRG LFAWLIPPSL NQRVELFQLN YLYTTIVSKI
LKILITFRIS NYFKYVPLKT QCTFIKFFLH QQACFIFSLI WSIGGSCDTD GRRVFDTFIR
LIILGKDDEN PVPDSVGKWE CPFDEKGLVY DYMYELKNKG RWVHWNELIK NTNLGDKQIK
IQDIIVPTMD TIRYTFLMDL SITYAKPLLF VGPTGTGKSV YVKDKLMNHL EKDQYFPFYI
NLSARTSANQ VQNIIMARLD KRRKGVFGPP MGKKCIIFID DMNMPALEKY GAQPPIELLR
QFFDCGHWYD LKDTSKITLV DIELIAAMGP PGGGRNPVTP RCIRHFNICS INSFSDETMV
RIFSSIVAFY LRTHEFPPEY FVIGNQIVNG TMEIYKQSVE NLLPTPTKSH YTFNLRDFSR
VIRGCLLIER DAVANKHTMI RLFVHEVLRV FYDRLINDDD RRWLFQLTKT VIKDHFKESF
HSIFSHLRKQ NAPVTEEDLR NLMFGDYMNP DLEGDDRVYI EIPNIHHFSD VVDQCLDEYN
QTHKTRMNLV IFRYVLEHLS RICRVLKQSG GNALLVGLGG SGRQSLTRLA TSMAKMHIFQ
PEISKSYGMN EWREDMKSFI AVPVTNRIVD NKSKILEKRL RYLNDHFTYN LYCNICRSLF
EKDKLLFSFL LCANLLLARK EIEYQELMFL LTGGVSLKSA EKNPDPTWLQ DKSWEEICRA
SEFPAFRGLR QHFCEHIYEW REIYDSKEPH NAKFPAPMDK NLNELQKIII LRCLRPDKIT
PAITNYVTDK LGKKFVEPPP FDLTKSYLDS NCTIPLIFVL SPGADPMASL LKFANDKSMS
GNKFQAISLG QGQGPIAAKM IKAAIEEGTW VCLQNCHLAV SWMPMLEKIC EDFTSETCNS
SFRLWLTSYP SSKFPVTILQ NGVKMTNEPP TGLRLNLLQS YLTDPVSDPE FFKGCRGKEL
AWEKLLFGVC FFHALVQERK KFGPLGWNIP YGFNESDLRI SIRQLQLFIN EYDTIPFEAI
SYLTGECNYG GRVTDDWDRR LLLTMLADFY NLYIVENPHY KFSPSGNYFA PPKGTYEDYI
EFIKKLPFTQ HPEIFGLHEN VDISKDLQQT KTLFESLLLT QGGSKQTGAS GSTDQILLEI
TKDILNKLPS DFDIEMALRK YPVRYEESMN TVLVQEMERF NNLIITIRNT LRDLEKAIKG
VVVMDSALEA LSGSLLVGKV PEIWAKRSYP SLKPLGSYIT DFLARLNFLQ DWYNSGKPCV
FWLSGFFFTQ AFLTGAMQNY ARKYTTPIDL LGYEFEVIPS DTSDTSPEDG VYIHGLYLDG
ARWDRESGLL AEQYPKLLFD LMPIIWIKPT QKSRIIKSDA YVCPLYKTSE RKGTLSTTGH
STNFVIAMLL KTDQPTRHWI KRGVALLCQL DD*

mutated AA sequence

MSDANKAAIA AEKEALNLKL PPIVHLPENI GADTPTQSKL LKYRRSKEQQ QKINQLVIDG
AKRNLDRTLG KRTPLLPPPD YPQTMTSEMK KKGFNYIYMK QCVESSPLVP IQQEWLDHML
RLIPESLKEG KEREELLESL INEVSSDFEN SMKRYLVQSV LVKPPVKSLE DEGGPLPESP
VGLDYSNPWH SSYVQARNQI FSNLHIIHPT MKMLLDLGYT TFADTVLLDF TGIRAKGPID
CESLKTDLSI QTRNAEEKIM NTWYPKVINL FTKKEALEGV KPEKLDAFYS CVSTLMSNQL
KDLLRRTVEG FVKLFDPKDQ QRLPIFKIEL TFDDDKMEFY PTFQDLEDNV LSLVERIAEA
LQNVQTIPSW LSGTSTPVNL DTELPEHVLH WAVDTLKAAV HRNLEGARKH YETYVEKYNW
LLDGTAVENI ETFQTEDHTF DEYTEFIEKF LSLASEIMLL PQWIHYTMVR LDCEDLKTGL
TNKAKAFANI LLNDIASKYR KENECICSEF EAIKEHALKV PETTEEMMDL ISYVEKARTV
GIEELILRIQ ESKRQMSYFL DVFLFPQEDL ALNATVLMWP RKINPIFDEN DELIENAKHK
KENELMAKRE KLILEIEKES RRMEEFTEFA ELERMQQYVT DVRQLQKRIQ ESEEAVQFIN
KEEELFKWEL TKYPELDKLK VNIEPYQKFF NFVLKWQRSE KRWMDGGFLD LNGESMEADV
EEFSREIFKT LKFFQTKLKK ELQEKRKAAR KRSLEEEKIE EEPKDNATIT MCRMRARHWK
QISEIVGYDL TPDSGTTLRK VLKLNLTPYL EQFEVISAGA SKEFSLEKAM NTMIGTWEDI
AFHISLYRDT GVCILSSVDE IQAILDDQII KTQTMRGSPF IKPFEHEIKA WEDRLIRIQE
TIDEWLKVQA QWLYLEPIFC SEDIMQQMPE EGRQFQTVDR HWRDIMKFCA KDPKVLAATS
LTGLLEKLQN CNELLEKIMK GLNAYLEKKR LFFPRFFFLS NDEMLEILSE TKDPLRVQPH
LKKCFEGIAK LEFLPNLDIK AMYSSEGERV ELIALISTSA ARGAVEKWLI QVEDLMLRSV
HDVIAAARLA YPESARRDWV REWPGQVVLC ISQMFWTSET QEVISGGTEG LKKYYKELQN
QLNEIVELVR GKLSKQTRTT LGALVTIDVH ARDVVMDMIK MGVSHDTDFL WLAQLRYYWE
NENARVRIIN CNVKYAYEYL GNSPRLVITP LTDRCYRTLI GAFYLNLGGA PEGPAGTGKT
ETTKDLAKAL AVQCVVFNCS DGLDYLAMGK FFKGLASSGA WACFDEFNRI ELEVLSVVAQ
QILCIQRAIQ QKLVVFVFEG TELKLNPNCF VAITMNPGYA GRSELPDNLK VLFRTVAMMV
PNYALIAEIS LYSYGFLNAR PLSVKIVMTY RLCSEQLSSQ FHYDYGMRAV KAVLVAAGNL
KLKYPNENED ILLLRSIKDV NEPKFLSHDI PLFNGITSDL FPGIKLPEAD YHEFLECAHE
ACNVHNLQPV KFFLEKIIQT YEMMIVRHGF MLVGEPFAAK TKVLHVLADT LTLMNEHGYG
EEEKVIYRTV NPKSITMGQL FGQFDPVSHE WTDGIVANTF REFALSETPD RKWVVFDGPI
DTLWIESMNT VLDDNKKLCL MSGEIIQMSP QMSLIFETMD LSQASPATVS RCGMIYLEPS
QLGWEPLVSS WLNSLKGPLC EPEYQALLRG LFAWLIPPSL NQRVELFQLN YLYTTIVSKI
LKILITFRIS NYFKYVPLKT QCTFIKFFLH QQACFIFSLI WSIGGSCDTD GRRVFDTFIR
LIILGKDDEN PVPDSVGKWE CPFDEKGLVY DYMYELKNKG RWVHWNELIK NTNLGDKQIK
IQDIIVPTMD TIRYTFLMDL SITYAKPLLF VGPTGTGKSV YVKDKLMNHL EKDQYFPFYI
NLSARTSANQ VQNIIMARLD KRRKGVFGPP MGKKCIIFID DMNMPALEKY GAQPPIELLR
QFFDCGHWYD LKDTSKITLV DIELIAAMGP PGGGRNPVTP RCIRHFNICS INSFSDETMV
RIFSSIVAFY LRTHEFPPEY FVIGNQIVNG TMEIYKQSVE NLLPTPTKSH YTFNLRDFSR
VIRGCLLIER DAVANKHTMI RLFVHEVLRV FYDRLINDDD RRWLFQLTKT VIKDHFKESF
HSIFSHLRKQ NAPVTEEDLR NLMFGDYMNP DLEGDDRVYI EIPNIHHFSD VVDQCLDEYN
QTHKTRMNLV IFRYVLEHLS RICRVLKQSG GNALLVGLGG SGRQSLTRLA TSMAKMHIFQ
PEISKSYGMN EWREDMKSFI AVPVTNRIVD NKSKILEKRL RYLNDHFTYN LYCNICRSLF
EKDKLLFSFL LCANLLLARK EIEYQELMFL LTGGVSLKSA EKNPDPTWLQ DKSWEEICRA
SEFPAFRGLR QHFCEHIYEW REIYDSKEPH NAKFPAPMDK NLNELQKIII LRCLRPDKIT
PAITNYVTDK LGKKFVEPPP FDLTKSYLDS NCTIPLIFVL SPGADPMASL LKFANDKSMS
GNKFQAISLG QGQGPIAAKM IKAAIEEGTW VCLQNCHLAV SWMPMLEKIC EDFTSETCNS
SFRLWLTSYP SSKFPVTILQ NGVKMTNEPP TGLRLNLLQS YLTDPVSDPE FFKGCRGKEL
AWEKLLFGVC FFHALVQERK KFGPLGWNIP YGFNESDLRI SIRQLQLFIN EYDTIPFEAI
SYLTGECNYG GRVTDDWDRR LLLTMLADFY NLYIVENPHY KFSPSGNYFA PPKGTYEDYI
EFIKKLPFTQ HPEIFGLHEN VDISKDLQQT KTLFESLLLT QGGSKQTGAS GSTDQILLEI
TKDILNKLPS DFDIEMALRK YPVRYEESMN TVLVQEMERF NNLIITIRNT LRDLEKAIKG
VVVMDSALEA LSGSLLVGKV PEIWAKRSYP SLKPLGSYIT DFLARLNFLQ DWYNSGKPCV
FWLSGFFFTQ AFLTGAMQNY ARKYTTPIDL LGYEFEVIPS DTSDTSPEDG VYIHGLYLDG
ARWDRESGLL AEQYPKLLFD LMPIIWIKPT QKSRIIKSDA YVCPLYKTSE RKGTLSTTGH
STNFVIAMLL KTDQPTRHWI KRGVALLCQL DD*

speed

0.67 s

MutationTaster - study a chromosomal position

Results

Taster files

mutation t@sting

Prediction

polymorphism

mutation t@sting

Prediction

polymorphism

mutation t@sting

Prediction

polymorphism

Problems