MutationTaster - study a chromosomal position

NEVER press reload or F5 - unless you want to start from the very beginning.
input seems to be ok - now mapping the variant to the different transcripts...
found 4 transcript(s)...
Querying Taster for transcript #1: ENST00000559087
Querying Taster for transcript #2: ENST00000245451
Querying Taster for transcript #3: ENST00000558984
Querying Taster for transcript #4: ENST00000417573
MT speed 0 s - this script 4.625439 s

Results

genesymbol	prediction	probability	model	prediction problem	splicing	ClinVar	amino acid changes	variant type	dbSNP ID	protein length	file
BMP4	polymorphism	0.020220563383639	simple_aae		affected		R287H	single base exchange	rs121912768		show file
BMP4	polymorphism	0.020220563383639	simple_aae		affected		R287H	single base exchange	rs121912768		show file
BMP4	polymorphism	0.020220563383639	simple_aae		affected		R287H	single base exchange	rs121912768		show file
BMP4	polymorphism	0.020220563383639	simple_aae		affected		R287H	single base exchange	rs121912768		show file

Taster files

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.979779436616361 (explain)

Summary

amino acid sequence changed
heterozygous in TGP or ExAC
known disease mutation at this position (HGMD CM091521)
protein features (might be) affected
splice site changes

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr14:54417117C>TN/A show variant in all transcripts IGV

HGNC symbol

BMP4

Ensembl transcript ID

ENST00000559087

Genbank transcript ID

NM_130850

UniProt peptide

P12644

alteration type

single base exchange

alteration region

CDS

DNA changes

c.860G>A
cDNA.1045G>A
g.8363G>A

AA changes

R287H Score: 29 explain score(s)

position(s) of altered AA
if AA alteration in CDS

287

frameshift

known variant

Reference ID: rs121912768

database	homozygous (T/T)	heterozygous	allele carriers
1000G	0	8	8
ExAC	0	91	91

known disease mutation at this position, please check HGMD for details (HGMD ID CM091521)

known disease mutation at this position, please check HGMD for details (HGMD ID CM091521)
known disease mutation at this position, please check HGMD for details (HGMD ID CM091521)

regulatory features

DNase1, Open Chromatin, DNase1 Hypersensitive Site
Gene Associated, Regulatory Feature, Gene associated regulatory feature
H3K27me3, Histone, Histone 3 Lysine 27 Tri-Methylation
H3K36me3, Histone, Histone 3 Lysine 36 Tri-Methylation
H3K4me2, Histone, Histone 3 Lysine 4 Di-Methylation
H3K4me3, Histone, Histone 3 Lysine 4 Tri-Methylation
H3K9ac, Histone, Histone 3 Lysine 9 Acetylation
Promoter Associated, Regulatory Feature, Promoter like regulatory feature

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.411	0.121
	0.412	0.142
(flanking)	1.934	0.178

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor increased	8363	wt: 0.87 / mu: 0.98	wt: CCGACGCCGGAGGGC mu: CCGACACCGGAGGGC	GACG\|ccgg
Donor gained	8365	0.35	mu: GACACCGGAGGGCCA	CACC\|ggag
Donor gained	8359	0.34	mu: TGACCCGACACCGGA	ACCC\|gaca

distance from splice site

490

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

287

mutated

not conserved

287

Ptroglodytes

all identical

ENSPTRG00000006358

287

Mmulatta

all identical

ENSMMUG00000000429

287

Fcatus

all identical

ENSFCAG00000004772

288

Mmusculus

all identical

ENSMUSG00000021835

288

Ggallus

no homologue

Trubripes

all identical

ENSTRUG00000014535

285

Drerio

all identical

ENSDARG00000019995

283

Dmelanogaster

all identical

FBgn0000490

456

DVSGGEGGGKGG

Celegans

no homologue

Xtropicalis

all identical

ENSXETG00000008620

282

protein features

start (aa)	end (aa)	feature	details
20	292	PROPEP	/FTId=PRO_0000033856.	lost
308	308	DISULFID	By similarity.	might get lost (downstream of altered splice site)
337	337	DISULFID	By similarity.	might get lost (downstream of altered splice site)
341	341	DISULFID	By similarity.	might get lost (downstream of altered splice site)
350	350	CARBOHYD	N-linked (GlcNAc...) (Potential).	might get lost (downstream of altered splice site)
365	365	CARBOHYD	N-linked (GlcNAc...) (Potential).	might get lost (downstream of altered splice site)
372	372	DISULFID	Interchain (By similarity).	might get lost (downstream of altered splice site)
372	372	DISULFID	Interchain (By similarity).	might get lost (downstream of altered splice site)
373	373	DISULFID	By similarity.	might get lost (downstream of altered splice site)
405	405	DISULFID	By similarity.	might get lost (downstream of altered splice site)
407	407	DISULFID	By similarity.	might get lost (downstream of altered splice site)

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

1227 / 1227

position (AA) of stopcodon in wt / mu AA sequence

409 / 409

position of stopcodon in wt / mu cDNA

1412 / 1412

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

186 / 186

chromosome

strand

-1

last intron/exon boundary

556

theoretical NMD boundary in CDS

320

length of CDS

1227

coding sequence (CDS) position

860

cDNA position
(for ins/del: last normal base / first normal base)

1045

gDNA position
(for ins/del: last normal base / first normal base)

8363

chromosomal position
(for ins/del: last normal base / first normal base)

54417117

original gDNA sequence snippet

GGGCCATGCCTTGACCCGACGCCGGAGGGCCAAGCGTAGCC

altered gDNA sequence snippet

GGGCCATGCCTTGACCCGACACCGGAGGGCCAAGCGTAGCC

original cDNA sequence snippet

GGGCCATGCCTTGACCCGACGCCGGAGGGCCAAGCGTAGCC

altered cDNA sequence snippet

GGGCCATGCCTTGACCCGACACCGGAGGGCCAAGCGTAGCC

wildtype AA sequence

MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT
LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEQIH STGLEYPERP ASRANTVRSF
HHEEHLENIP GTSENSAFRF LFNLSSIPEN EVISSAELRL FREQVDQGPD WERGFHRINI
YEVMKPPAEV VPGHLITRLL DTRLVHHNVT RWETFDVSPA VLRWTREKQP NYGLAIEVTH
LHQTRTHQGQ HVRISRSLPQ GSGNWAQLRP LLVTFGHDGR GHALTRRRRA KRSPKHHSQR
ARKKNKNCRR HSLYVDFSDV GWNDWIVAPP GYQAFYCHGD CPFPLADHLN STNHAIVQTL
VNSVNSSIPK ACCVPTELSA ISMLYLDEYD KVVLKNYQEM VVEGCGCR*

mutated AA sequence

MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT
LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEQIH STGLEYPERP ASRANTVRSF
HHEEHLENIP GTSENSAFRF LFNLSSIPEN EVISSAELRL FREQVDQGPD WERGFHRINI
YEVMKPPAEV VPGHLITRLL DTRLVHHNVT RWETFDVSPA VLRWTREKQP NYGLAIEVTH
LHQTRTHQGQ HVRISRSLPQ GSGNWAQLRP LLVTFGHDGR GHALTRHRRA KRSPKHHSQR
ARKKNKNCRR HSLYVDFSDV GWNDWIVAPP GYQAFYCHGD CPFPLADHLN STNHAIVQTL
VNSVNSSIPK ACCVPTELSA ISMLYLDEYD KVVLKNYQEM VVEGCGCR*

speed

0.98 s

All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.979779436616361 (explain)

Summary

amino acid sequence changed
heterozygous in TGP or ExAC
known disease mutation at this position (HGMD CM091521)
protein features (might be) affected
splice site changes

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr14:54417117C>TN/A show variant in all transcripts IGV

HGNC symbol

BMP4

Ensembl transcript ID

ENST00000245451

Genbank transcript ID

NM_001202

UniProt peptide

P12644

alteration type

single base exchange

alteration region

CDS

DNA changes

c.860G>A
cDNA.1254G>A
g.8363G>A

AA changes

R287H Score: 29 explain score(s)

position(s) of altered AA
if AA alteration in CDS

287

frameshift

known variant

Reference ID: rs121912768

database	homozygous (T/T)	heterozygous	allele carriers
1000G	0	8	8
ExAC	0	91	91

regulatory features

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.411	0.121
	0.412	0.142
(flanking)	1.934	0.178

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor increased	8363	wt: 0.87 / mu: 0.98	wt: CCGACGCCGGAGGGC mu: CCGACACCGGAGGGC	GACG\|ccgg
Donor gained	8365	0.35	mu: GACACCGGAGGGCCA	CACC\|ggag
Donor gained	8359	0.34	mu: TGACCCGACACCGGA	ACCC\|gaca

distance from splice site

490

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

287

mutated

not conserved

287

Ptroglodytes

all identical

ENSPTRG00000006358

287

Mmulatta

all identical

ENSMMUG00000000429

287

Fcatus

all identical

ENSFCAG00000004772

288

Mmusculus

all identical

ENSMUSG00000021835

288

Ggallus

no homologue

Trubripes

all identical

ENSTRUG00000014535

285

Drerio

all identical

ENSDARG00000019995

283

Dmelanogaster

all identical

FBgn0000490

456

DVSGGEGGGKGG

Celegans

no homologue

Xtropicalis

all identical

ENSXETG00000008620

282

protein features

start (aa)	end (aa)	feature	details
20	292	PROPEP	/FTId=PRO_0000033856.	lost
308	308	DISULFID	By similarity.	might get lost (downstream of altered splice site)
337	337	DISULFID	By similarity.	might get lost (downstream of altered splice site)
341	341	DISULFID	By similarity.	might get lost (downstream of altered splice site)
350	350	CARBOHYD	N-linked (GlcNAc...) (Potential).	might get lost (downstream of altered splice site)
365	365	CARBOHYD	N-linked (GlcNAc...) (Potential).	might get lost (downstream of altered splice site)
372	372	DISULFID	Interchain (By similarity).	might get lost (downstream of altered splice site)
372	372	DISULFID	Interchain (By similarity).	might get lost (downstream of altered splice site)
373	373	DISULFID	By similarity.	might get lost (downstream of altered splice site)
405	405	DISULFID	By similarity.	might get lost (downstream of altered splice site)
407	407	DISULFID	By similarity.	might get lost (downstream of altered splice site)

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

1227 / 1227

position (AA) of stopcodon in wt / mu AA sequence

409 / 409

position of stopcodon in wt / mu cDNA

1621 / 1621

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

395 / 395

chromosome

strand

-1

last intron/exon boundary

765

theoretical NMD boundary in CDS

320

length of CDS

1227

coding sequence (CDS) position

860

cDNA position
(for ins/del: last normal base / first normal base)

1254

gDNA position
(for ins/del: last normal base / first normal base)

8363

chromosomal position
(for ins/del: last normal base / first normal base)

54417117

original gDNA sequence snippet

GGGCCATGCCTTGACCCGACGCCGGAGGGCCAAGCGTAGCC

altered gDNA sequence snippet

GGGCCATGCCTTGACCCGACACCGGAGGGCCAAGCGTAGCC

original cDNA sequence snippet

GGGCCATGCCTTGACCCGACGCCGGAGGGCCAAGCGTAGCC

altered cDNA sequence snippet

GGGCCATGCCTTGACCCGACACCGGAGGGCCAAGCGTAGCC

wildtype AA sequence

mutated AA sequence

MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT
LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEQIH STGLEYPERP ASRANTVRSF
HHEEHLENIP GTSENSAFRF LFNLSSIPEN EVISSAELRL FREQVDQGPD WERGFHRINI
YEVMKPPAEV VPGHLITRLL DTRLVHHNVT RWETFDVSPA VLRWTREKQP NYGLAIEVTH
LHQTRTHQGQ HVRISRSLPQ GSGNWAQLRP LLVTFGHDGR GHALTRHRRA KRSPKHHSQR
ARKKNKNCRR HSLYVDFSDV GWNDWIVAPP GYQAFYCHGD CPFPLADHLN STNHAIVQTL
VNSVNSSIPK ACCVPTELSA ISMLYLDEYD KVVLKNYQEM VVEGCGCR*

speed

0.75 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.979779436616361 (explain)

Summary

amino acid sequence changed
heterozygous in TGP or ExAC
known disease mutation at this position (HGMD CM091521)
protein features (might be) affected
splice site changes

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr14:54417117C>TN/A show variant in all transcripts IGV

HGNC symbol

BMP4

Ensembl transcript ID

ENST00000558984

Genbank transcript ID

N/A

UniProt peptide

P12644

alteration type

single base exchange

alteration region

CDS

DNA changes

c.860G>A
cDNA.1047G>A
g.8363G>A

AA changes

R287H Score: 29 explain score(s)

position(s) of altered AA
if AA alteration in CDS

287

frameshift

known variant

Reference ID: rs121912768

database	homozygous (T/T)	heterozygous	allele carriers
1000G	0	8	8
ExAC	0	91	91

regulatory features

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.411	0.121
	0.412	0.142
(flanking)	1.934	0.178

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor increased	8363	wt: 0.87 / mu: 0.98	wt: CCGACGCCGGAGGGC mu: CCGACACCGGAGGGC	GACG\|ccgg
Donor gained	8365	0.35	mu: GACACCGGAGGGCCA	CACC\|ggag
Donor gained	8359	0.34	mu: TGACCCGACACCGGA	ACCC\|gaca

distance from splice site

490

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

287

mutated

not conserved

287

Ptroglodytes

all identical

ENSPTRG00000006358

287

Mmulatta

all identical

ENSMMUG00000000429

287

Fcatus

all identical

ENSFCAG00000004772

288

Mmusculus

all identical

ENSMUSG00000021835

288

Ggallus

no homologue

Trubripes

all identical

ENSTRUG00000014535

285

Drerio

all identical

ENSDARG00000019995

283

Dmelanogaster

all identical

FBgn0000490

456

DVSGGEGGGKGG

Celegans

no homologue

Xtropicalis

all identical

ENSXETG00000008620

282

protein features

start (aa)	end (aa)	feature	details
20	292	PROPEP	/FTId=PRO_0000033856.	lost
308	308	DISULFID	By similarity.	might get lost (downstream of altered splice site)
337	337	DISULFID	By similarity.	might get lost (downstream of altered splice site)
341	341	DISULFID	By similarity.	might get lost (downstream of altered splice site)
350	350	CARBOHYD	N-linked (GlcNAc...) (Potential).	might get lost (downstream of altered splice site)
365	365	CARBOHYD	N-linked (GlcNAc...) (Potential).	might get lost (downstream of altered splice site)
372	372	DISULFID	Interchain (By similarity).	might get lost (downstream of altered splice site)
372	372	DISULFID	Interchain (By similarity).	might get lost (downstream of altered splice site)
373	373	DISULFID	By similarity.	might get lost (downstream of altered splice site)
405	405	DISULFID	By similarity.	might get lost (downstream of altered splice site)
407	407	DISULFID	By similarity.	might get lost (downstream of altered splice site)

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

1227 / 1227

position (AA) of stopcodon in wt / mu AA sequence

409 / 409

position of stopcodon in wt / mu cDNA

1414 / 1414

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

188 / 188

chromosome

strand

-1

last intron/exon boundary

558

theoretical NMD boundary in CDS

320

length of CDS

1227

coding sequence (CDS) position

860

cDNA position
(for ins/del: last normal base / first normal base)

1047

gDNA position
(for ins/del: last normal base / first normal base)

8363

chromosomal position
(for ins/del: last normal base / first normal base)

54417117

original gDNA sequence snippet

GGGCCATGCCTTGACCCGACGCCGGAGGGCCAAGCGTAGCC

altered gDNA sequence snippet

GGGCCATGCCTTGACCCGACACCGGAGGGCCAAGCGTAGCC

original cDNA sequence snippet

GGGCCATGCCTTGACCCGACGCCGGAGGGCCAAGCGTAGCC

altered cDNA sequence snippet

GGGCCATGCCTTGACCCGACACCGGAGGGCCAAGCGTAGCC

wildtype AA sequence

mutated AA sequence

MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT
LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEQIH STGLEYPERP ASRANTVRSF
HHEEHLENIP GTSENSAFRF LFNLSSIPEN EVISSAELRL FREQVDQGPD WERGFHRINI
YEVMKPPAEV VPGHLITRLL DTRLVHHNVT RWETFDVSPA VLRWTREKQP NYGLAIEVTH
LHQTRTHQGQ HVRISRSLPQ GSGNWAQLRP LLVTFGHDGR GHALTRHRRA KRSPKHHSQR
ARKKNKNCRR HSLYVDFSDV GWNDWIVAPP GYQAFYCHGD CPFPLADHLN STNHAIVQTL
VNSVNSSIPK ACCVPTELSA ISMLYLDEYD KVVLKNYQEM VVEGCGCR*

speed

0.94 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 0.979779436616361 (explain)

Summary

amino acid sequence changed
heterozygous in TGP or ExAC
known disease mutation at this position (HGMD CM091521)
protein features (might be) affected
splice site changes

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr14:54417117C>TN/A show variant in all transcripts IGV

HGNC symbol

BMP4

Ensembl transcript ID

ENST00000417573

Genbank transcript ID

NM_130851

UniProt peptide

P12644

alteration type

single base exchange

alteration region

CDS

DNA changes

c.860G>A
cDNA.1124G>A
g.8363G>A

AA changes

R287H Score: 29 explain score(s)

position(s) of altered AA
if AA alteration in CDS

287

frameshift

known variant

Reference ID: rs121912768

database	homozygous (T/T)	heterozygous	allele carriers
1000G	0	8	8
ExAC	0	91	91

regulatory features

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	0.411	0.121
	0.412	0.142
(flanking)	1.934	0.178

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

effect	gDNA position	score	wt detection sequence	exon-intron border
Donor increased	8363	wt: 0.87 / mu: 0.98	wt: CCGACGCCGGAGGGC mu: CCGACACCGGAGGGC	GACG\|ccgg
Donor gained	8365	0.35	mu: GACACCGGAGGGCCA	CACC\|ggag
Donor gained	8359	0.34	mu: TGACCCGACACCGGA	ACCC\|gaca

distance from splice site

490

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

287

mutated

not conserved

287

Ptroglodytes

all identical

ENSPTRG00000006358

287

Mmulatta

all identical

ENSMMUG00000000429

287

Fcatus

all identical

ENSFCAG00000004772

288

Mmusculus

all identical

ENSMUSG00000021835

288

Ggallus

no homologue

Trubripes

all identical

ENSTRUG00000014535

285

Drerio

all identical

ENSDARG00000019995

283

Dmelanogaster

all identical

FBgn0000490

456

DVSGGEGGGKGG

Celegans

no homologue

Xtropicalis

all identical

ENSXETG00000008620

282

protein features

start (aa)	end (aa)	feature	details
20	292	PROPEP	/FTId=PRO_0000033856.	lost
308	308	DISULFID	By similarity.	might get lost (downstream of altered splice site)
337	337	DISULFID	By similarity.	might get lost (downstream of altered splice site)
341	341	DISULFID	By similarity.	might get lost (downstream of altered splice site)
350	350	CARBOHYD	N-linked (GlcNAc...) (Potential).	might get lost (downstream of altered splice site)
365	365	CARBOHYD	N-linked (GlcNAc...) (Potential).	might get lost (downstream of altered splice site)
372	372	DISULFID	Interchain (By similarity).	might get lost (downstream of altered splice site)
372	372	DISULFID	Interchain (By similarity).	might get lost (downstream of altered splice site)
373	373	DISULFID	By similarity.	might get lost (downstream of altered splice site)
405	405	DISULFID	By similarity.	might get lost (downstream of altered splice site)
407	407	DISULFID	By similarity.	might get lost (downstream of altered splice site)

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

1227 / 1227

position (AA) of stopcodon in wt / mu AA sequence

409 / 409

position of stopcodon in wt / mu cDNA

1491 / 1491

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

265 / 265

chromosome

strand

-1

last intron/exon boundary

635

theoretical NMD boundary in CDS

320

length of CDS

1227

coding sequence (CDS) position

860

cDNA position
(for ins/del: last normal base / first normal base)

1124

gDNA position
(for ins/del: last normal base / first normal base)

8363

chromosomal position
(for ins/del: last normal base / first normal base)

54417117

original gDNA sequence snippet

GGGCCATGCCTTGACCCGACGCCGGAGGGCCAAGCGTAGCC

altered gDNA sequence snippet

GGGCCATGCCTTGACCCGACACCGGAGGGCCAAGCGTAGCC

original cDNA sequence snippet

GGGCCATGCCTTGACCCGACGCCGGAGGGCCAAGCGTAGCC

altered cDNA sequence snippet

GGGCCATGCCTTGACCCGACACCGGAGGGCCAAGCGTAGCC

wildtype AA sequence

mutated AA sequence

MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT
LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEQIH STGLEYPERP ASRANTVRSF
HHEEHLENIP GTSENSAFRF LFNLSSIPEN EVISSAELRL FREQVDQGPD WERGFHRINI
YEVMKPPAEV VPGHLITRLL DTRLVHHNVT RWETFDVSPA VLRWTREKQP NYGLAIEVTH
LHQTRTHQGQ HVRISRSLPQ GSGNWAQLRP LLVTFGHDGR GHALTRHRRA KRSPKHHSQR
ARKKNKNCRR HSLYVDFSDV GWNDWIVAPP GYQAFYCHGD CPFPLADHLN STNHAIVQTL
VNSVNSSIPK ACCVPTELSA ISMLYLDEYD KVVLKNYQEM VVEGCGCR*

speed

0.67 s

MutationTaster - study a chromosomal position

Results

Taster files

mutation t@sting

Prediction

polymorphism

mutation t@sting

Prediction

polymorphism

mutation t@sting

Prediction

polymorphism

mutation t@sting

Prediction

polymorphism

Problems