MutationTaster - study a chromosomal position

NEVER press reload or F5 - unless you want to start from the very beginning.
input seems to be ok - now mapping the variant to the different transcripts...
found 3 transcript(s)...
Querying Taster for transcript #1: ENST00000389297
Querying Taster for transcript #2: ENST00000497910
Querying Taster for transcript #3: ENST00000316089
MT speed 0 s - this script 3.10974 s

Results

genesymbol	prediction	probability	model	prediction problem	splicing	ClinVar	amino acid changes	variant type	dbSNP ID	protein length	file
CFAP69	polymorphism_automatic	0.99994904446941	simple_aae		affected		T885M	single base exchange	rs1134956		show file
CFAP69	polymorphism_automatic	0.99994904446941	simple_aae		affected		T867M	single base exchange	rs1134956		show file
CFAP69	polymorphism_automatic	0.99994904446941	simple_aae		affected		T839M	single base exchange	rs1134956		show file

Taster files

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 5.09555305895111e-05 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
splice site changes

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr7:89938680C>TN/A show variant in all transcripts IGV

HGNC symbol

CFAP69

Ensembl transcript ID

ENST00000389297

Genbank transcript ID

NM_001039706

UniProt peptide

A5D8W1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.2654C>T
cDNA.2905C>T
g.64193C>T

AA changes

T885M Score: 81 explain score(s)

position(s) of altered AA
if AA alteration in CDS

885

frameshift

known variant

Reference ID: rs1134956

database	homozygous (T/T)	heterozygous	allele carriers
1000G	401	1104	1505
ExAC	16272	223	16495

regulatory features

N/A

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	3.553	1
	4.256	1
(flanking)	0.546	1

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

alteration within used splice site, likely to disturb normal splicing

effect	gDNA position	score	detection sequence	exon-intron border
Donor lost	64193	sequence motif lost	-	wt: AACG\|gtaa mu: AATG.gtaa
Donor marginally decreased	64193	wt: 0.9932 / mu: 0.9801 (marginal change - not scored)	wt: CACAACGGTAAGATT mu: CACAATGGTAAGATT	CAAC\|ggta

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

885

mutated

not conserved

885

Ptroglodytes

all identical

ENSPTRG00000019383

839

Mmulatta

all identical

ENSMMUG00000023654

557

Fcatus

no homologue

Mmusculus

all identical

ENSMUSG00000040473

886

Ggallus

all identical

ENSGALG00000009026

844

Trubripes

no homologue

Drerio

no homologue

Dmelanogaster

no homologue

Celegans

no homologue

Xtropicalis

all identical

ENSXETG00000007441

844

protein features

no protein features affected

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2826 / 2826

position (AA) of stopcodon in wt / mu AA sequence

942 / 942

position of stopcodon in wt / mu cDNA

3077 / 3077

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

252 / 252

chromosome

strand

last intron/exon boundary

2907

theoretical NMD boundary in CDS

2605

length of CDS

2826

coding sequence (CDS) position

2654

cDNA position
(for ins/del: last normal base / first normal base)

2905

gDNA position
(for ins/del: last normal base / first normal base)

64193

chromosomal position
(for ins/del: last normal base / first normal base)

89938680

original gDNA sequence snippet

TATTAAAGGCCTTAACACAACGGTAAGATTCTTTCTCCATA

altered gDNA sequence snippet

TATTAAAGGCCTTAACACAATGGTAAGATTCTTTCTCCATA

original cDNA sequence snippet

TATTAAAGGCCTTAACACAACGGTGCCCTCTGGTGGAGTAG

altered cDNA sequence snippet

TATTAAAGGCCTTAACACAATGGTGCCCTCTGGTGGAGTAG

wildtype AA sequence

MWTEEAGATA EAQESGIRNK SSSSSQIPVV GVVTEDDEAQ DVFKPMDLNR VIKLLEETDK
DGLEEKQLKF VKKLVQCYQN GLPLRDLAQI FKILNLCSGK IKNQPRFIES AYDIIKLCGL
PFLKKKVSDE ITYAEDTANS IALLGDLMKI PSSELRIQIC KCIVDFYHAE PPKKHIPGYQ
QASSSYKIQM AEVGGLAKTM VQSMTLLENQ LVEKLWVLKV LQHLSTSEVN CTIMMKAQAA
SGICTHLNDP DPSGQLLFRS SEILWNLLEK SSKEEVIQQL SNLECLLALK EVFKNLFMRG
FSHYDRQLRN DILVITTIIA QNPEAPMIEC GFTKDLILFA TFNEVKSQNL LVKGLKLSNS
YEDFELKKLL FNVIVILCKD LPTVQLLIDG KVILALFTYV KKPEKQKIID WSAAQHEELQ
LHAIATLSSV APLLIEEYMS CQGNARVLAF LEWCESEDPF FSHGNSFHGT GGRGNKFAQM
RYSLRLLRAV VYLEDETVNK DLCEKGTIQQ MIGIFKNIIS KPNEKEEAIV LEIQSDILLI
LSGLCENHIQ RKEIFGTEGV DIVLHVMKTD PRKLQSGLGY NVLLFSTLDS IWCCILGCYP
SEDYFLEKEG IFLLLDLLAL NQKKFCNLIL GIMVEFCDNP KTAAHVNAWQ GKKDQTAASL
LIKLWRKEEK ELGVKRDKNG KIIDTKKPLF TSFQEEQKII PLPANCPSIA VMDVSENIRA
KIYAILGKLD FENLPGLSAE DFVTLCIIHR YLDFKIGEIW NEIYEEIKLE KLRPVTTDKK
ALEAITTASE NIGKMVASLQ SDIIESQACQ DMQNEQKVYA KIQATHKQRE LANKSWEDFL
ARTSNAKTLK KAKSLQEKAI EASRYHKRPQ NAIFHQTHIK GLNTTVPSGG VVTVESTPAR
LVGGPLVDTD IALKKLPIRG GALQRVKAVK IVDAPKKSIP T*

mutated AA sequence

MWTEEAGATA EAQESGIRNK SSSSSQIPVV GVVTEDDEAQ DVFKPMDLNR VIKLLEETDK
DGLEEKQLKF VKKLVQCYQN GLPLRDLAQI FKILNLCSGK IKNQPRFIES AYDIIKLCGL
PFLKKKVSDE ITYAEDTANS IALLGDLMKI PSSELRIQIC KCIVDFYHAE PPKKHIPGYQ
QASSSYKIQM AEVGGLAKTM VQSMTLLENQ LVEKLWVLKV LQHLSTSEVN CTIMMKAQAA
SGICTHLNDP DPSGQLLFRS SEILWNLLEK SSKEEVIQQL SNLECLLALK EVFKNLFMRG
FSHYDRQLRN DILVITTIIA QNPEAPMIEC GFTKDLILFA TFNEVKSQNL LVKGLKLSNS
YEDFELKKLL FNVIVILCKD LPTVQLLIDG KVILALFTYV KKPEKQKIID WSAAQHEELQ
LHAIATLSSV APLLIEEYMS CQGNARVLAF LEWCESEDPF FSHGNSFHGT GGRGNKFAQM
RYSLRLLRAV VYLEDETVNK DLCEKGTIQQ MIGIFKNIIS KPNEKEEAIV LEIQSDILLI
LSGLCENHIQ RKEIFGTEGV DIVLHVMKTD PRKLQSGLGY NVLLFSTLDS IWCCILGCYP
SEDYFLEKEG IFLLLDLLAL NQKKFCNLIL GIMVEFCDNP KTAAHVNAWQ GKKDQTAASL
LIKLWRKEEK ELGVKRDKNG KIIDTKKPLF TSFQEEQKII PLPANCPSIA VMDVSENIRA
KIYAILGKLD FENLPGLSAE DFVTLCIIHR YLDFKIGEIW NEIYEEIKLE KLRPVTTDKK
ALEAITTASE NIGKMVASLQ SDIIESQACQ DMQNEQKVYA KIQATHKQRE LANKSWEDFL
ARTSNAKTLK KAKSLQEKAI EASRYHKRPQ NAIFHQTHIK GLNTMVPSGG VVTVESTPAR
LVGGPLVDTD IALKKLPIRG GALQRVKAVK IVDAPKKSIP T*

speed

0.45 s

All positions are in basepairs (bp) if not explicitly stated differently.
AA/aa: amino acid; CDS: coding sequence; mu: mutated; NMD: nonsense-mediated mRNA decay; nt: nucleotide; wt: wildtype; TGP: 1000 Genomes Project
back to results table

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 5.09555305895111e-05 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
splice site changes

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr7:89938680C>TN/A show variant in all transcripts IGV

HGNC symbol

CFAP69

Ensembl transcript ID

ENST00000497910

Genbank transcript ID

NM_001160138

UniProt peptide

A5D8W1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.2600C>T
cDNA.2810C>T
g.64193C>T

AA changes

T867M Score: 81 explain score(s)

position(s) of altered AA
if AA alteration in CDS

867

frameshift

known variant

Reference ID: rs1134956

database	homozygous (T/T)	heterozygous	allele carriers
1000G	401	1104	1505
ExAC	16272	223	16495

regulatory features

N/A

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	3.553	1
	4.256	1
(flanking)	0.546	1

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

alteration within used splice site, likely to disturb normal splicing

effect	gDNA position	score	detection sequence	exon-intron border
Donor lost	64193	sequence motif lost	-	wt: AACG\|gtaa mu: AATG.gtaa
Donor marginally decreased	64193	wt: 0.9932 / mu: 0.9801 (marginal change - not scored)	wt: CACAACGGTAAGATT mu: CACAATGGTAAGATT	CAAC\|ggta

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

867

mutated

not conserved

867

Ptroglodytes

all identical

ENSPTRG00000019383

839

Mmulatta

all identical

ENSMMUG00000023654

557

Fcatus

no homologue

Mmusculus

all identical

ENSMUSG00000040473

886

Ggallus

all identical

ENSGALG00000009026

844

Trubripes

no homologue

Drerio

no homologue

Dmelanogaster

no homologue

Celegans

no homologue

Xtropicalis

all identical

ENSXETG00000007441

844

protein features

no protein features affected

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2772 / 2772

position (AA) of stopcodon in wt / mu AA sequence

924 / 924

position of stopcodon in wt / mu cDNA

2982 / 2982

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

211 / 211

chromosome

strand

last intron/exon boundary

2812

theoretical NMD boundary in CDS

2551

length of CDS

2772

coding sequence (CDS) position

2600

cDNA position
(for ins/del: last normal base / first normal base)

2810

gDNA position
(for ins/del: last normal base / first normal base)

64193

chromosomal position
(for ins/del: last normal base / first normal base)

89938680

original gDNA sequence snippet

TATTAAAGGCCTTAACACAACGGTAAGATTCTTTCTCCATA

altered gDNA sequence snippet

TATTAAAGGCCTTAACACAATGGTAAGATTCTTTCTCCATA

original cDNA sequence snippet

TATTAAAGGCCTTAACACAACGGTGCCCTCTGGTGGAGTAG

altered cDNA sequence snippet

TATTAAAGGCCTTAACACAATGGTGCCCTCTGGTGGAGTAG

wildtype AA sequence

MWTEEAGATA EAQESGIRNK SSSSSQIPVV GVVTEDDEAQ DVFKPMDLNR VIKLLEETDK
DGLEEKQLKF VKKLVQCYQN GLPLRDLAQI FKILNLCSGK IKNQPRFIES AYDIIKLCGL
PFLKKKVSDE ITYAEDTANS IALLGDLMKI PSSELRIQIC YQQASSSYKI QMAEVGGLAK
TMVQSMTLLE NQLVEKLWVL KVLQHLSTSE VNCTIMMKAQ AASGICTHLN DPDPSGQLLF
RSSEILWNLL EKSSKEEVIQ QLSNLECLLA LKEVFKNLFM RGFSHYDRQL RNDILVITTI
IAQNPEAPMI ECGFTKDLIL FATFNEVKSQ NLLVKGLKLS NSYEDFELKK LLFNVIVILC
KDLPTVQLLI DGKVILALFT YVKKPEKQKI IDWSAAQHEE LQLHAIATLS SVAPLLIEEY
MSCQGNARVL AFLEWCESED PFFSHGNSFH GTGGRGNKFA QMRYSLRLLR AVVYLEDETV
NKDLCEKGTI QQMIGIFKNI ISKPNEKEEA IVLEIQSDIL LILSGLCENH IQRKEIFGTE
GVDIVLHVMK TDPRKLQSGL GYNVLLFSTL DSIWCCILGC YPSEDYFLEK EGIFLLLDLL
ALNQKKFCNL ILGIMVEFCD NPKTAAHVNA WQGKKDQTAA SLLIKLWRKE EKELGVKRDK
NGKIIDTKKP LFTSFQEEQK IIPLPANCPS IAVMDVSENI RAKIYAILGK LDFENLPGLS
AEDFVTLCII HRYLDFKIGE IWNEIYEEIK LEKLRPVTTD KKALEAITTA SENIGKMVAS
LQSDIIESQA CQDMQNEQKV YAKIQATHKQ RELANKSWED FLARTSNAKT LKKAKSLQEK
AIEASRYHKR PQNAIFHQTH IKGLNTTVPS GGVVTVESTP ARLVGGPLVD TDIALKKLPI
RGGALQRVKA VKIVDAPKKS IPT*

mutated AA sequence

MWTEEAGATA EAQESGIRNK SSSSSQIPVV GVVTEDDEAQ DVFKPMDLNR VIKLLEETDK
DGLEEKQLKF VKKLVQCYQN GLPLRDLAQI FKILNLCSGK IKNQPRFIES AYDIIKLCGL
PFLKKKVSDE ITYAEDTANS IALLGDLMKI PSSELRIQIC YQQASSSYKI QMAEVGGLAK
TMVQSMTLLE NQLVEKLWVL KVLQHLSTSE VNCTIMMKAQ AASGICTHLN DPDPSGQLLF
RSSEILWNLL EKSSKEEVIQ QLSNLECLLA LKEVFKNLFM RGFSHYDRQL RNDILVITTI
IAQNPEAPMI ECGFTKDLIL FATFNEVKSQ NLLVKGLKLS NSYEDFELKK LLFNVIVILC
KDLPTVQLLI DGKVILALFT YVKKPEKQKI IDWSAAQHEE LQLHAIATLS SVAPLLIEEY
MSCQGNARVL AFLEWCESED PFFSHGNSFH GTGGRGNKFA QMRYSLRLLR AVVYLEDETV
NKDLCEKGTI QQMIGIFKNI ISKPNEKEEA IVLEIQSDIL LILSGLCENH IQRKEIFGTE
GVDIVLHVMK TDPRKLQSGL GYNVLLFSTL DSIWCCILGC YPSEDYFLEK EGIFLLLDLL
ALNQKKFCNL ILGIMVEFCD NPKTAAHVNA WQGKKDQTAA SLLIKLWRKE EKELGVKRDK
NGKIIDTKKP LFTSFQEEQK IIPLPANCPS IAVMDVSENI RAKIYAILGK LDFENLPGLS
AEDFVTLCII HRYLDFKIGE IWNEIYEEIK LEKLRPVTTD KKALEAITTA SENIGKMVAS
LQSDIIESQA CQDMQNEQKV YAKIQATHKQ RELANKSWED FLARTSNAKT LKKAKSLQEK
AIEASRYHKR PQNAIFHQTH IKGLNTMVPS GGVVTVESTP ARLVGGPLVD TDIALKKLPI
RGGALQRVKA VKIVDAPKKS IPT*

speed

0.61 s

mutation t@sting

documentation

Prediction

polymorphism

Model: simple_aae, prob: 5.09555305895111e-05 (classification due to TGP/ExAC, real probability is shown anyway) (explain)

Summary

amino acid sequence changed
homozygous in TGP or ExAC
protein features (might be) affected
splice site changes

hyperlink

analysed issue

analysis result

name of alteration

no title

alteration (phys. location)

chr7:89938680C>TN/A show variant in all transcripts IGV

HGNC symbol

CFAP69

Ensembl transcript ID

ENST00000316089

Genbank transcript ID

N/A

UniProt peptide

A5D8W1

alteration type

single base exchange

alteration region

CDS

DNA changes

c.2516C>T
cDNA.2767C>T
g.64193C>T

AA changes

T839M Score: 81 explain score(s)

position(s) of altered AA
if AA alteration in CDS

839

frameshift

known variant

Reference ID: rs1134956

database	homozygous (T/T)	heterozygous	allele carriers
1000G	401	1104	1505
ExAC	16272	223	16495

regulatory features

N/A

phyloP / phastCons

	PhyloP	PhastCons
(flanking)	3.553	1
	4.256	1
(flanking)	0.546	1

explain score(s) and/or inspect your position(s) in in UCSC Genome Browser

splice sites

alteration within used splice site, likely to disturb normal splicing

effect	gDNA position	score	detection sequence	exon-intron border
Donor lost	64193	sequence motif lost	-	wt: AACG\|gtaa mu: AATG.gtaa
Donor marginally decreased	64193	wt: 0.9932 / mu: 0.9801 (marginal change - not scored)	wt: CACAACGGTAAGATT mu: CACAATGGTAAGATT	CAAC\|ggta

distance from splice site

Kozak consensus sequence altered?

N/A

conservation
protein level for non-synonymous changes

species

match

gene

alignment

Human

839

mutated

not conserved

839

Ptroglodytes

all identical

ENSPTRG00000019383

839

Mmulatta

all identical

ENSMMUG00000023654

557

Fcatus

no homologue

Mmusculus

all identical

ENSMUSG00000040473

886

Ggallus

all identical

ENSGALG00000009026

844

Trubripes

no homologue

Drerio

no homologue

Dmelanogaster

no homologue

Celegans

no homologue

Xtropicalis

all identical

ENSXETG00000007441

844

protein features

start (aa)	end (aa)	feature	details
854	854	CONFLICT	S -> R (in Ref. 2; BAB14972/BAG63878/ BAG64159 and 4; AAI32772/AAI41835/ AAI42656).	might get lost (downstream of altered splice site)

length of protein

normal

AA sequence altered

yes

position of stopcodon in wt / mu CDS

2688 / 2688

position (AA) of stopcodon in wt / mu AA sequence

896 / 896

position of stopcodon in wt / mu cDNA

2939 / 2939

poly(A) signal

N/A

conservation
nucleotide level for all changes - no scoring up to now

N/A

position of start ATG in wt / mu cDNA

252 / 252

chromosome

strand

last intron/exon boundary

2769

theoretical NMD boundary in CDS

2467

length of CDS

2688

coding sequence (CDS) position

2516

cDNA position
(for ins/del: last normal base / first normal base)

2767

gDNA position
(for ins/del: last normal base / first normal base)

64193

chromosomal position
(for ins/del: last normal base / first normal base)

89938680

original gDNA sequence snippet

TATTAAAGGCCTTAACACAACGGTAAGATTCTTTCTCCATA

altered gDNA sequence snippet

TATTAAAGGCCTTAACACAATGGTAAGATTCTTTCTCCATA

original cDNA sequence snippet

TATTAAAGGCCTTAACACAACGGTGCCCTCTGGTGGAGTAG

altered cDNA sequence snippet

TATTAAAGGCCTTAACACAATGGTGCCCTCTGGTGGAGTAG

wildtype AA sequence

MWTEEAGATA EAQESGIRNK SSSSSQIPVV GVVTEDDEAQ DVFKPMDLNR VIKLLEETDK
DGLEEKQLKF VKKLVQCYQN GLPLRDLAQI FKILNLCSGK IKNQPRFIES AYDIIKLCGL
PFLKKKVSDE ITYAEDTANS IALLGDLMKI PSSELRIQIC KCIVDFYHAE PPKKHIPGYQ
QASSSYKIQM AEVGGLAKTM VQSMTLLENQ LVEKLWVLKV LQHLSTSEVN CTIMMKAQAA
SGICTHLNDP DPSGQLLFRS SEILWNLLEK SSKEEVIQQL SNLECLLALK EVFKNLFMRG
FSHYDRQLRN DILVITTIIA QNPEAPMIEC GFTKDLILFA TFNEVKSQNL LVKGLKLSNS
YEDFELKKLL FNVIVILCKD LPTVQLLIDG KVILALFTYV KKPEKQKIID WSAAQHEELQ
LHAIATLSSV APLLIEEYMS CQGNARVLAF LEWCESEDPF FSHGNSFHGT GGRGNKFAQM
RYSLRLLRAV VYLEDETVNK DLCEKGTIQQ MIGIFKNIIS KPNEKEEAIV LEIQSDILLI
LSGLCENHIQ RKEIFGTEGV DIVLHVMKTD PRKLQSGLGY NVLLFSTLDS IWCCILGCYP
SEDYFLEKEG IFLLLDLLAL NQKKFCNLIL GIMVEFCDNP KTAAHVNAWQ GKKDQTAASL
LIKLWRKEEK ELGVKRDKNG KIIDFENLPG LSAEDFVTLC IIHRYLDFKI GEIWNEIYEE
IKLEKLRPVT TDKKALEAIT TASENIGKMV ASLQSDIIES QACQDMQNEQ KVYAKIQATH
KQRELANKSW EDFLARTSNA KTLKKAKSLQ EKAIEASRYH KRPQNAIFHQ THIKGLNTTV
PSGGVVTVES TPARLVGGPL VDTDIALKKL PIRGGALQRV KAVKIVDAPK KSIPT*

mutated AA sequence

MWTEEAGATA EAQESGIRNK SSSSSQIPVV GVVTEDDEAQ DVFKPMDLNR VIKLLEETDK
DGLEEKQLKF VKKLVQCYQN GLPLRDLAQI FKILNLCSGK IKNQPRFIES AYDIIKLCGL
PFLKKKVSDE ITYAEDTANS IALLGDLMKI PSSELRIQIC KCIVDFYHAE PPKKHIPGYQ
QASSSYKIQM AEVGGLAKTM VQSMTLLENQ LVEKLWVLKV LQHLSTSEVN CTIMMKAQAA
SGICTHLNDP DPSGQLLFRS SEILWNLLEK SSKEEVIQQL SNLECLLALK EVFKNLFMRG
FSHYDRQLRN DILVITTIIA QNPEAPMIEC GFTKDLILFA TFNEVKSQNL LVKGLKLSNS
YEDFELKKLL FNVIVILCKD LPTVQLLIDG KVILALFTYV KKPEKQKIID WSAAQHEELQ
LHAIATLSSV APLLIEEYMS CQGNARVLAF LEWCESEDPF FSHGNSFHGT GGRGNKFAQM
RYSLRLLRAV VYLEDETVNK DLCEKGTIQQ MIGIFKNIIS KPNEKEEAIV LEIQSDILLI
LSGLCENHIQ RKEIFGTEGV DIVLHVMKTD PRKLQSGLGY NVLLFSTLDS IWCCILGCYP
SEDYFLEKEG IFLLLDLLAL NQKKFCNLIL GIMVEFCDNP KTAAHVNAWQ GKKDQTAASL
LIKLWRKEEK ELGVKRDKNG KIIDFENLPG LSAEDFVTLC IIHRYLDFKI GEIWNEIYEE
IKLEKLRPVT TDKKALEAIT TASENIGKMV ASLQSDIIES QACQDMQNEQ KVYAKIQATH
KQRELANKSW EDFLARTSNA KTLKKAKSLQ EKAIEASRYH KRPQNAIFHQ THIKGLNTMV
PSGGVVTVES TPARLVGGPL VDTDIALKKL PIRGGALQRV KAVKIVDAPK KSIPT*

speed

0.52 s

MutationTaster - study a chromosomal position

Results

Taster files

mutation t@sting

Prediction

polymorphism

mutation t@sting

Prediction

polymorphism

mutation t@sting

Prediction

polymorphism

Problems